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In vitro evaluation of ginsenoside Rg1 immunostimulating effect in bovine mononuclear cells
(Elsevier, 2023-05)The aim of this study was to evaluate the immunomodulatory effect of ginsenoside Rg1 on mammary secretion and peripheral blood mononuclear cells (MSMC and PBMC, respectively). The mRNA expression of TLR2, TLR4 and selected ... -
Intramammary inoculation of Panax ginseng plays an immunoprotective role in Staphylococcus aureus infection in a murine model
(2017-12)The immunoprotective effect of Panax ginseng (Pg) extract was investigated in a mouse mastitis model. Lactating female mice were intramammarily inoculated with Pg or placebo, and then were challenged with S. aureus, while ... -
Involvement of matrix metalloproteinases and their inhibitors in Staphylococcus aureus chronically infected bovine mammary glands during active involution
(Elsevier, 2021-04)The aim of this study was to characterize the protein expression of matrix metalloproteinase-2 (MMP-2) and ‐− 9 and their inhibitors (TIMP-1 and -2) in mammary tissue of dairy cows with naturally occurring chronic S. aureus ... -
Liposomal and CpG-ODN formulation elicits strong humoral immune responses to recombinant Staphylococcus aureus antigens in heifer calves
(Elsevier, 2019-05-01)Bovine mastitis caused by Staphylococcus aureus is a serious problem in dairy production and effective immunoprophylaxis is an unmet goal so far. The objective of this work was to assess the humoral immune response of ... -
Panax ginseng extract reduces Staphylococcus aureus internalization into bovine mammary epithelial cells but does not affect macrophages phagocytic activity
(2018-09)Panax ginseng extract (PGe) has been shown to possess immunomodulatory effects in healthy dairy cows at drying off and to trigger an adequate immune response to protect from an experimental intramammary infection (IMI) ... -
Preparation and characterization of a Staphylococcus aureus capsular polysaccharide-protein conjugate prepared by a low cost technique: a proof-of-concept study
(2015-01)Staphylococcus aureus is a worldwide distributed pathogen that produces several diseases in many species and is the major cause of mastitis in dairy cows. S. aureus capsular polysaccharide 5 (CP5) has been widely proposed ... -
Prevalencia de bacterias patógenas de mastitis bovina en leche de tanque de frío y evaluación de medios de cultivos para el recuento y la identificación de Staphylococcus aureus
(2014)El objetivo del presente estudio fue estimar la prevalencia de bacterias patógenas de mastitis en muestras de leche de tanque en tambos ubicados en la cuenca lechera central Argentina. Además, se evaluó el desempeño de ... -
Proliferation-apoptosis balance in Staphylococcus aureus chronically infected bovine mammary glands during involution
(2017-05)The objective of this study was to determine whether Staphylococcus aureus chronic intramammary infection (IMI) influences expression of proteins related to regulation of proliferation and apoptosis processes and ... -
Staphylococcus aureus chronic intramammary infection modifies protein expression of transforming growth factor beta (TGF-β) subfamily components during active involution
(2014-02)The objectives of this study were to determine whether Staphylococcus aureus chronic intramammary infection (IMI) influences protein expression of TGF-β subfamily components and collagen I and to examine the histomorphometric ... -
Survey of potential factors involved in the low frequency of CP5 and CP8 expression in Staphylococcus aureus isolates from mastitis of dairy cattle from Argentina, Chile, and Uruguay
(2018-08)Staphylococcus aureus produces capsular polysaccharides (CPs) both in vivo and under defined culture conditions being serotypes 5 and 8 the most prevalent. S. aureus isolates that fail to produce CP5 or CP8 are defined as ... -
Susceptibilidad a antibióticos de Staphylococcus aureus aislados de mastitis bovina en lecherías de la cuenca central de Argentina
(2016-09)La mastitis bovina causa cuantiosas pérdidas económicas al productor lechero y la industria láctea a nivel mundial. Staphylococcus aureus es uno de los principales patógenos mayores causantes de infecciones intramamarias, ... -
Which are important targets in development of S. aureus mastitis vaccine?
(2015-06)Staphylococcus aureus represents one of the leading causes of mastitis in dairy cows worldwide. S. aureus IMI have variable outcomes due to virulence of the strain involved, immune defenses of the host, and by antibiotic ...