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Characterization of a Nanovaccine Platform Based on an α1,2- Mannobiose Derivative Shows Species-non-specific Targeting to Human, Bovine, Mouse, and Teleost Fish Dendritic Cells
Pappalardo, Juan Sebastián; Salmaso, Stefano; Levchenko, Tatyana S.; Mastrotto, Francesca; Bersani, Sara; Vermeulen, Monica; Ghersa, Federica; Quattrocchi, Valeria; Zamorano, Patricia Ines; Hartner, William C.; Toniutti, Micaela; Musacchio, Tiziana; Torchilin, Vladimir P. (ACS Publications, 2021-07)Dendritic cells serve as the main immune cells that trigger the immune response. We developed a simple and cost-effective nanovaccine platform based on the α1′,2-mannobiose derivative for dendritic cell targeting. In ... -
Dendritic cell targeting in cultured fish in Argentina for vaccine development
Ghersa, Federica; Soria, Ivana; Quattrocchi, Valeria; Gammella, Mariela; Langellotti, Cecilia Ana; Zamorano, Patricia Ines; Rauque, Carlos Alejandro; Pappalardo, Juan Sebastián (Edición del Autor, 2019)In Argentina two main species present an important economic value, these are Pacú (Piaractus mesopotamicus, Pm) and Rainbow Trout (Oncorhynchus mykiss, Om). Due to stress and changing environmental conditions cultured fish ... -
Effects of polydopamine-passivation on the optical properties of carbon dots and its potential use in vivo
Pappalardo, Juan Sebastián; Macairan, Jun-Ray; Macina, Alexia; Poulhazan, Alexandre; Quattrocchi, Valeria; Marcotte, Isabelle; Naccache, Rafik (Royal Society of Chemistry, 2020-07)Passivation of carbon dots via heteroatom doping has been shown to enhance their optical properties and tune their fluorescence signature. Additionally, the incorporation of polymeric precursors in carbon dot synthesis has ...