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Cytokine expression profile of B. melitensis-infected goat monocyte-derived macrophages
(Elsevier, 2023-05)Brucella parasitize the macrophage where is able to replicate and modulate the immune response in order to establish a chronic infection. The most adequate response to control and eliminate Brucella infection is a type 1 ... -
Genetic analysis of the 3′ untranslated region of the bovine SLC11A1 gene reveals novel polymorphisms
(Springer, 2013-01)Polymorphisms in microsatellites at the 3′ untranslated region (3′UTR) of the SLC11A1 (solute carrier family 11 member A1) gene have been associated with natural resistance to Brucella abortus and Mycobacterium bovis ... -
A haplotype at intron 8 of PTPRT gene is associated with resistance to Brucella infection in Argentinian creole goats
(2017-08)Brucellosis is the leading zoonosis on a worldwide scale and constitutes a major public health threat in many regions of the world. Several molecular markers associated with natural resistance to intracellular bacterial ... -
Incomplete sterols and hopanoids pathways in ciliates: Gene loss and acquisition during evolution as a source of biosynthetic genes
(Elsevier, 2014-05)Polycyclic triterpenoids, such as sterols and hopanoids, are essential components of plasmatic membrane in eukaryotic organisms. Although it is generally assumed that ciliates do not synthesize sterols, and many of them ... -
Molecular characterization of Cryptosporidium isolates from calves in Argentina
(2013-12)Cryptosporidiosis is responsible for significant fatalities of neonatal calves, resulting in substantial economic loss in dairy farming in several countries. Additionally, the high shedding of environmentally resistant ... -
Plant-based vaccine for livestock : key points to unleash platform translation in developing countries
(2016-12)Ten years ago the first plant-based vaccine was licensed (DowAgrosciences). It was only 20 years after the first report of a recombinant protein obtained through plant transformation technology. Back then, this vaccine was ... -
Polymorphisms at the 3′ untranslated region of SLC11A1 gene are associated with protection to Brucella infection in goats
(Elsevier, 2014-08-15)Goats are susceptible to brucellosis and the detection of Brucella-infected animals is carried out by serological tests. In other ruminant species, polymorphisms in microsatellites (Ms) of 3′ untranslated region (3′UTR) ... -
Systems biology analysis of temporal in vivo Brucella melitensis and bovine transcriptomes predicts host : pathogen protein–protein interactions
(2017-07)To date, fewer than 200 gene-products have been identified as Brucella virulence factors, and most were characterized individually without considering how they are temporally and coordinately expressed or secreted during ... -
Use of the Leptospira sp. ligB C-terminus coding region as a diagnostic tool of animal leptospirosis
(Elsevier, 2021-10)Leptospirosis is the most widespread zoonosis worldwide, and it can cause reproductive failures in livestock, while in humans may vary from a mild fever to multi-organ failure and death. Due to this, in this study, we ...