Temas 

Temas

Mostrando ítems 1-11 de 11

    • A novel bacterial protease inhibitor adjuvant in RBD-based COVID-19 vaccine formulations containing alum increases neutralizing antibodies, specific germinal center B cells and confers protection against SARS-CoV-2 infection in mice 

      Coria, Lorena M.; Saposnik, Lucas M.; Pueblas Castro, Celeste; Castro, Eliana Florencia; Bruno, Laura A.; Stone, William B.; Pérez, Paula S.; Darriba, Maria Laura; Chemes, Lucia B.; Alcain, Julieta; Mazzitelli, Ignacio; Varese, Augusto; Salvatori, Melina; Auguste, Albert J.; Álvarez, Diego E.; Pasquevich, Karina A.; Cassataro, Juliana (Frontiers Media, 2022-02)
      In this work, we evaluated recombinant receptor binding domain (RBD)-based vaccine formulation prototypes with potential for further clinical development. We assessed different formulations containing RBD plus alum, AddaS03, ...

    • Anthropogenic infection of domestic cats with SARS-CoV-2 alpha variant B.1.1.7 lineage in Buenos Aires 

      Pecora, Andrea; Malacari, Darío Amilcar; Mozgovoj, Marina Valeria; Díaz, María de los Ángeles; Peralta, Andrea Veronica; Cacciabue, Marco Polo Domingo; Puebla, Andrea Fabiana; Carusso, Cristian; Mundo, Silvia Leonor; Gonzalez Lopez Ledesma, María Mora; Gamarnik, Andrea Vanesa; Rinaldi, Osvaldo; Vidal, Osvaldo; Mas, Javier; Dus Santos, Maria Jose (Frontiers Media, 2022-03)
      SARS-CoV-2 reverse zoonosis, particularly to domestic animals, and the potential role of infected animals in perpetuating the spread of the virus is an issue of increasing concern. In this case report, we identified the ...

    • Assessing the hidden diversity underlying consensus sequences of SARS-CoV-2 using VICOS, a novel bioinformatic pipeline for identification of mixed viral populations 

      Goya, Stephanie; Sosa, Ezequiel Jorge; Nabaes Jodar, Mercedes Soledad; Torres, Carolina; Konig, Guido Alberto; Acuña, Dolores; Ceballos, Santiago; Distefano, Ana Julia; Dopazo, Hernán; Dus Santos, Maria Jose; Fass, Monica Irinia; Fernandez Do Porto, Darío Augusto; Fernandez, Ailen; Gallego, Fernando; Gismondi, Maria Ines; Gramundi, Ivan; Lusso, Silvina; Marti, Marcelo Adrián; Mazzeo, Melina; Mistchenko, Alicia Susana; Muñoz Hidalgo, Marianne Graziel; Natale, Mónica; Nardi, Cristina; Ousset, Julia; Peralta, Andrea Veronica; Pintos, Carolina; Puebla, Andrea Fabiana; Pianciola, Luis; Rivarola, Maximo Lisandro; Turjanski, Adrián; Valinotto, Laura; Vera, Pablo Alfredo; Zaiat, Jonathan; Zubrycki, Jeremias Enrique; Aulicino, Paula; Viegas, Mariana (Elsevier, 2023-02)
      Introduction: Coinfection with two SARS-CoV-2 viruses is still a very understudied phenomenon. Although next generation sequencing methods are very sensitive to detect heterogeneous viral populations in a sample, there is ...

    • Development and evaluation of a low cost IgG ELISA test based in RBD protein for COVID-19 

      Villafañe, Luciana María; Gallo Vaulet, Maria Lucia; Viere, Florencia M.; Klepp, Laura Ines; Forrellad, Marina Andrea; Bigi, María Mercedes; Romano, Maria Isabel; Magistrelli, Giovanni; Rodríguez Fermepin, Marcelo; Bigi, Fabiana (Elsevier, 2022-01)
      Serology tests for SARS-CoV-2 have proven to be important tools to fight against the COVID-19 pandemic. These serological tests can be used in low-income and remote areas for patient contact tracing, epidemiologic studies ...

    • Development of nanobody-displayed whole-cell biosensors for the colorimetric detection of SARS-CoV‑2 

      He, Yawen; Xu, Zhiyuan; Kasputis, Tom; Zhao, Xue; Ibañez, Itati; Pavan, Florencia; Bok, Marina; Malito, Juan Pablo; Parreño, Gladys Viviana; Yuan, Lijuan; Wright, R. Clay; Chen, Juhong (American Chemical Society, 2023-08)
      The accurate and effective detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is essential to preventing the spread of infectious diseases and ensuring human health. Herein, a nanobody-displayed ...

    • Evaluation of a lyophilized CRISPR-Cas12 assay for a sensitive, specific, and rapid detection of SARS-CoV-2 

      Curti, Lucía Ana; Primost, Ivana; Valla, Sofia; Ibañez Alegre, Daiana; Olguin Perglione, Cecilia; Repizo, Guillermo Daniel; Lara, Julia; Parcerisa, Ivana; Palacios, Antonela; Llases, María Eugenia; Rinflerch, Adriana; Barrios, Melanie; Pereyra Bonnet, Federico; Gimenez, Carla Alejandra; Marcone, Débora Natalia (MDPI, 2021-03)
      We evaluated a lyophilized CRISPR-Cas12 assay for SARS-CoV-2 detection (Lyo-CRISPR SARS-CoV-2 kit) based on reverse transcription, isothermal amplification, and CRISPR-Cas12 reaction. From a total of 210 RNA samples extracted ...

    • Longitudinal follow-up of the immunity to SARS-CoV-2 in health care workers in Argentina : persistence of humoral response and neutralizing capacity after Sputnik V vaccination 

      Castro, Eliana Florencia; Acosta, Julián; Moriena, Lucía; Rios Medrano, Mayra; Cibello, Malena Tejerina; Codino, Eduardo; Taborda, Miguel Ángel; Álvarez, Diego E.; Cavatorta, Ana (American Society for Microbiology, 2023-06)
      SARS-CoV-2 vaccine protection has encountered waning of immune response and breakthrough infections. The hybrid immune response generated by the combination of vaccination and infection was shown to offer higher and broader ...

    • Rapid and cost-effective process based on insect larvae for scale-up production of SARS-COV-2 spike protein for serological COVID-19 testing 

      Smith, Ignacio; Mc Callum, Gregorio Juan; Sabljic, Adriana Victoria; Marfia, Juan Ignacio; Bombicino, Silvina Sonia; Trabucchi, Aldana; Iacono, Ruben Francisco; Birenbaum, Joaquín Manuel; Vazquez, Susana Claudia; Minoia, Juan Mauricio; Cascone, Osvaldo; Lopez, Maria Gabriela; Taboga, Oscar Alberto; Targovnik, Alexandra Marisa; Wolman, Federico Javier; Fingermann, Matías; Alonso, Leonardo Gabriel; Valdez, Silvina Noemí; Miranda, María Victoria (Wiley, 2021-10)
      Serology testing for COVID-19 is important in evaluating active immune response against SARS-CoV-2, studying the antibody kinetics, and monitoring reinfections with genetic variants and new virus strains, in particular, ...

    • SARS-CoV-2 RBD protein enhances the oncolytic activity of the vesicular stomatitis virus 

      Alkayyal, Almohanad A.; Ajina, Reham; Cacciabue, Marco Polo Domingo; Alkayyal, Aaesha A.; Saeedi, Nizar H.; Hussain Alshehry, Taofik; Kaboha, Feras; Alotaibi, Mohammed A.; Zaidan, Nada; Shah, Khalid; Alroqi, Fayhan; Bakur Mahmoud, Ahmad (Frontiers Media, 2023-01)
      Despite recent advances in the research on oncolytic viruses (OVs), a better understanding of how to enhance their replication is key to improving their therapeutic index. Understanding viral replication is important to ...

    • Serological evidence of SARS-CoV-2 infection in pets naturally exposed during the COVID-19 outbreak in Argentina 

      Panei, Carlos Javier; Bravi, María Emilia; More, Gastón; de Felice, Lorena Alejandra; Unzaga, Juan Manuel; Salina, Marcos D.; Rivero, Fernando David; Di Lullo, David; Pecoraro, Marcelo; Alvarez, Diego Ezequiel; Castro, Eliana Florencia; Fuentealba, Nadia Analía (Elsevier, 2022-12)
      Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent of coronavirus disease 2019 (COVID-19), has rapidly spread worldwide. The monitoring of animals has shown that certain species may be ...

    • Serological screening of SARS-CoV-2 infection in companion animals of Buenos Aires suburbs 

      Cardoso, Nancy; Rivero, Carla; Castillo, Mariangeles; Mansilla, Florencia Celeste; Pastorino, Florencia; Piccirilli, Guadalupe; Alonso, Laura; Martinez, Gustavo; Di Lullo, David; Bentancor, Leticia Veronica; Capozzo, Alejandra (Frontiers Media, 2023-05)
      The Coronavirus Disease 2019 (COVID-19) is a zoonotic disease caused by the pandemic virus SARS-CoV-2. Domestic and wild animals are susceptible to infection and are potential reservoirs for virus variants. To date, there ...