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Mostrando ítems 1-2 de 2

    • A simple and economic three-step process for producing highly purified Fab’ fragments directly from the egg yolk water-soluble fraction 

      González Viacava, Myriam Belén; Leiva, Carlos Leónidas; Tavarone, Maria Eugenia; Dokmetjian, José Christian; Cascone, Osvaldo; Chacana, Pablo; Fingermann, Matías (Elsevier, 2022-11)
      Although mammals are still the main source of polyclonal antibodies production, the use of egg yolk immunoglobulins (IgY) is increasing, and thus improvement of its safety to reduce undesired reactions is needed. Removal ...

    • Development of a platform process for the production and purification of single‐domain antibodies 

      Crowell, Laura E.; Goodwine, Chaz; Sosa Holt, Carla Solange; Rocha, Lucía Alejandra; Vega, Celina Guadalupe; Rodriguez-Aponte, Sergio A.; Dalvie, Neil C.; Tracey, Mary Kate; Puntel, Mariana; Wigdorovitz, Andres; Parreño, Gladys; Love, Kerry R.; Cramer, Steven M.; Love, J. Christopher (Wiley, 2021-09)
      Single-domain antibodies (sdAbs) offer the affinity and therapeutic value of conventional antibodies, with increased stability and solubility. Unlike conventional antibodies, however, sdAbs do not benefit from a platform ...