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Mostrando ítems 1-15 de 15
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Alfalfa snakin-1 prevents fungal colonization and probably coevolved with rhizobia
(BMC Plant Biology, 2014-09-17)Background: The production of antimicrobial peptides is a common defense strategy of living cells against a wide range of pathogens. Plant snakin peptides inhibit bacterial and fungal growth at extremely low concentrations. ... -
An inhibitory mechanism of action of coiled‐coil peptides against type three secretion system from enteropathogenic Escherichia coli
(Wiley, 2019-03)Human pathogenic gram‐negative bacteria, such as enteropathogenic Escherichia coli (EPEC), rely on type III secretion systems (T3SS) to translocate virulence factors directly into host cells. The coiled‐coil domains present ... -
Análisis funcional de Snakin - 1 en plantas transgénicas de Solanum tuberosum
(Facultad de Agronomía, Universidad de Buenos Aires, 2015-04)Snakin-1 (SN1)es un péptido antimicrobiano rico en cisteínas aislado a partir de Solanum tuberosum que fue clasificado como miembro de la familia Snakin/GASA. Con el objetivo de estudiar el rol de SN1 in planta, se realizó ... -
Dendrimeric peptides can confer protection against foot-and-mouth disease virus in cattle
(2017-09)Foot-and-mouth disease virus (FMDV) causes a highly contagious disease in cloven-hoofed animals. A synthetic vaccine candidate consisting of dendrimeric peptides harbouring two copies of a B-epitope [VP1(136–154)] linked ... -
Immune Response and Partial Protection against Heterologous Foot-and-Mouth Disease Virus Induced by Dendrimer Peptides in Cattle
(2018-04)Synthetic peptides mimicking protective B- and T-cell epitopes are good candidates for safer, more effective FMD vaccines. Nevertheless, previous studies of immunization with linear peptides showed that they failed to ... -
Isolation and characterization of the tissue and development-specific potato snakin-1 promoter inducible by temperature and wounding
(Pontificia Universidad Catolica de Valparaiso, 2010-09)Snakin-1 (StSN1) is a broad-spectrum antimicrobial peptide isolated from Solanum tuberosum. Homologous proteins have been identified in a wide range of species but there is no apparent consensus in the roles they play. A ... -
Novel biotechnological platform based on baculovirus occlusion bodies carrying Babesia bovis small antigenic peptides for the design of a diagnostic enzyme-linked immunosorbent assay (ELISA)
(Springer, 2018-01)Baculoviruses are large DNA virus of insects principally employed in recombinant protein expression. Its ability to form occlusion bodies (OBs), which are composed mainly of polyhedrin protein (POLH), makes them ... -
Potato Snakin-1 Gene Silencing Affects Cell Division, Primary Metabolism, and Cell Wall Composition
(American Society of Plant Biologists, 2012-01)Snakin-1 (SN1) is an antimicrobial cysteine-rich peptide isolated from potato (Solanum tuberosum) that was classified as a member of the Snakin/Gibberellic Acid Stimulated in Arabidopsis protein family. In this work, a ... -
Potato snakin‑1: an antimicrobial player of the trade‑off between host defense and development
(Springer, 2020-07)Snakin-1 (SN1) from potato is a cysteine-rich antimicrobial peptide with high evolutionary conservation. It has 63 amino acid residues, 12 of which are cysteines capable of forming six disulfide bonds. SN1 localizes in the ... -
Pseudomonas fluorescens Pf-5 genome-wide mutant screen for resistance to the antimicrobial peptide alfalfa snakin-1
(Oxford University Press, 2015-01)Snakin-1, a peptide produced by higher plants, has broad-spectrum antibiotic activity, inhibiting organisms ranging from Bacteria to Eukaryotes. However, the mode of action against target organisms is poorly understood. ... -
Review of antiviral peptides for use against zoonotic and selected non-zoonotic viruses
(Elsevier, 2021-08)Viruses remain one of the leading causes of animal and human disease. Some animal viral infections spread sporadically to human populations, posing a serious health risk. Particularly the emerging viral zoonotic diseases ... -
Rol de las toxinas binarias en las enfermedades intestinales causadas por clostridios enterotóxicos
(Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, 2015-03)Las enfermedades digestivas causadas por especies del genero Clostridium poseen un importante impacto en la medicina tanto humana como veterinaria. Entre las especies patógenas más importantes de este género se encuentran ... -
Snakin/GASA proteins : involvement in hormone crosstalk and redox homeostasis
(Taylor & Francis, 2012)Snakin/GASA proteins are widely distributed among plant species. They are expressed in different plant organs with high tissue and temporal specificity, and their subcellular localization varies among the different members. ... -
Successful production of the potato antimicrobial peptide Snakin-1 in baculovirus-infected insect cells and development of specific antibodies
(2017)Background: Snakin-1 (StSN1) is a broad-spectrum antimicrobial cysteine-rich peptide isolated from Solanum tuberosum. Its biotechnological potential has been already recognized since it exhibits in vivo antifungal and ... -
Transgenic citrange troyer rootstocks overexpressing antimicrobial potato snakin-1 show reduced citrus canker disease symptoms
(Elsevier, 2020-12)Citrus canker is a major disease caused by Xanthomonas citri pv. citri. Snakin-1 is an antimicrobial peptide, which was previously shown to be effective against different bacterial and fungal diseases in potato, wheat and ...