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Mostrando ítems 1-5 de 5

    • Experimental selection of long‐term intracellular mycobacteria 

      Vazquez, Cristina Lourdes; Lerner, Thomas R.; Kasmapour, Bahram; Pei, Gang; Gronow, Achim; Bianco, María Veronica; Blanco, Federico Carlos; Bleck, Christopher K.E.; Geffers, Robert; Bigi, Fabiana; Abraham, Wolf-Rainer; Gutierrez, Maximiliano Gabriel (Wiley, 2014-09)
      Some intracellular bacteria are known to cause long‐term infections that last decades without compromising the viability of the host. Although of critical importance, the adaptations that intracellular bacteria undergo ...

    • Mycobacterium bovis requires P27 (LprG) to arrest phagosome maturation and replicate within bovine macrophages 

      Vazquez, Cristina Lourdes; Bianco, María Veronica; Blanco, Federico Carlos; Forrellad, Marina Andrea; Gutierrez, Maximiliano Gabriel; Bigi, Fabiana (2017-03)
      Mycobacterium bovis causes tuberculosis in a wide variety of mammals, with strong tropism for cattle and eventually humans. P27, also called LprG, is among the proteins involved in the mechanisms of the virulence and ...

    • Rv2577 of Mycobacterium tuberculosis is a virulence factor with dual phosphatase and phosphodiesterase functions 

      Forrellad, Marina Andrea; Blanco, Federico Carlos; Marrero Diaz De Vill, Rubén; Vazquez, Cristina Lourdes; Yaneff, Agustín; Garcia, Elizabeth Andrea; Gutierrez, Maximiliano Gabriel; Durán, Rosario; Villarino, Andrea; Bigi, Fabiana (Frontiers Media, 2020-10)
      Tuberculosis, a lung disease caused by Mycobacterium tuberculosis (Mtb), is one of the ten leading causes of death worldwide affecting mainly developing countries. Mtb can persist and survive inside infected cells through ...

    • Rv2617c and P36 are virulence factors of pathogenic mycobacteria involved in resistance to oxidative stress 

      Forrellad, Marina Andrea; Vazquez, Cristina Lourdes; Blanco, Federico Carlos; Klepp, Laura Ines; Garcia, Elizabeth Andrea; Rocha, Rosana Valeria; Villafañe, Luciana Maria; Bigi, María Mercedes; Gutierrez, Maximiliano Gabriel; Bigi, Fabiana (Taylor & Francis, 2019-12)
      In this study, we characterized the role of Rv2617c in the virulence of Mycobacterium tuberculosis. Rv2617c is a protein of unknown function unique to M. tuberculosis complex (MTC) and Mycobacterium leprae. In vitro, this ...

    • Study of the in vivo role of Mce2R, the transcriptional regulator of mce2 operon in Mycobacterium tuberculosis 

      Forrellad, Marina Andrea; Bianco, María Veronica; Blanco, Federico Carlos; Nuñez, Javier; Klepp, Laura Ines; Vazquez, Cristina Lourdes; Santangelo, María De La Paz; Rocha, Rosana Valeria; Soria, Marcelo; Golby, Paul; Gutierrez, Maximiliano Gabriel; Bigi, Fabiana (BMC, 2013-09)
      Background: Tuberculosis is one of the leading causes of mortality throughout the world. Mycobacterium tuberculosis, the agent of human tuberculosis, has developed strategies involving proteins and other compounds called ...