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A computational study of the interaction of the foot and mouth disease virus VP1 with monoclonal antibodies
(Elsevier, 2015-10)Foot and mouth disease is caused by a non-enveloped virus (FMDV), which disposes several antigenic sites at the surface of their capsid proteins. The most relevant and immunodominant antigenic site of FMDV (site A or AnSA) ... -
Análisis genómico de girasol: desarrollo de colecciones de ESTs y de una plataforma bioinformática para estudios de expresión de genes candidato en respuestas a estreses abióticos
(Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 2006)El girasol es uno de los principales cultivos oleaginosos del mundo por su volumen de producción y composición en ácidos grasos insaturados. En promedio, durante los últimos cinco años, la producción mundial se ha mantenido ... -
Assessing the hidden diversity underlying consensus sequences of SARS-CoV-2 using VICOS, a novel bioinformatic pipeline for identification of mixed viral populations
(Elsevier, 2023-02)Introduction: Coinfection with two SARS-CoV-2 viruses is still a very understudied phenomenon. Although next generation sequencing methods are very sensitive to detect heterogeneous viral populations in a sample, there is ... -
Caracterización de candidatos vacunales de Cryptosporidium parvum
(Universidad de Morón, 2017-10)La criptosporidiosis bovina es causada por el protozoo apicomplexa Cryptosporidium spp. y es una enfermedad desatendida a nivel global y local. Es una zoonosis y antroponosis que afecta a inmunosuprimidos y a niños menores ... -
Draft genome sequence data of Cercospora kikuchii, a causal agent of Cercospora leaf blight and purple seed stain of soybeans
(Elsevier, 2019-10)Cercospora kikuchii (Tak. Matsumoto & Tomoy.) M.W. Gardner 1927 is an ascomycete fungal pathogen that causes Cercospora leaf blight and purple seed stain on soybean. Here, we report the first draft genome sequence and ... -
Improving clustering with metabolic pathway data
(BMC, 2014-04)Background: It is a common practice in bioinformatics to validate each group returned by a clustering algorithm through manual analysis, according to a-priori biological knowledge. This procedure helps finding functionally ... -
LOV‐domain photoreceptor, encoded in a genomic island, attenuates the virulence of Pseudomonas syringae in light‐exposed Arabidopsis leaves
(Wiley, 2013-10)In Arabidopsis thaliana, light signals modulate the defences against bacteria. Here we show that light perceived by the LOV domain‐regulated two‐component system (Pst–Lov) of Pseudomonas syringae pv. tomato DC3000 (Pst ... -
Methodology for the identification of relevant loci for milk traits in dairy cattle, using machine learning algorithms
(Elsevier, 2022)Machine learning methods were considered efficient in identifying single nucleotide polymorphisms (SNP) underlying a trait of interest. This study aimed to construct predictive models using machine learning algorithms, to ... -
Structural and molecular dynamics investigations of ligand stabilization via secondary binding site interactions in Paenibacillus xylanivorans GH11 xylanase
(Elsevier, 2021-03)Glycoside hydrolases (GHs) are essential for plant biomass deconstruction. GH11 family consist of endo-β-1,4-xylanases which hydrolyze xylan, the second most abundant cell wall biopolymer after cellulose, into small ... -
The key to egress? Babesia bovis perforin-like protein 1 (PLP1) with hemolytic capacity is required for blood stage replication and is involved in the exit of the parasite from the host cell
(Elsevier, 2021-07)Bovine babesiosis is a tick-borne disease caused by apicomplexan parasites of the Babesia genus that represents a major constraint to livestock production worldwide. Currently available vaccines are based on live parasites ... -
Unraveling the complexity of the rhomboid serine protease 4 family of Babesia bovis using bioinformatics and experimental studies
(MDPI, 2022-03)Babesia bovis, a tick-transmitted apicomplexan protozoon, infects cattle in tropical and subtropical regions around the world. In the apicomplexans Toxoplasma gondii and Plasmodium falciparum, rhomboid serine protease 4 ... -
ViralPlaque: a Fiji macro for automated assessment of viral plaque statistics
(PeerJ, 2019-09)laque assay has been used for a long time to determine infectious titers and characterize prokaryotic and eukaryotic viruses forming plaques. Indeed, plaque morphology and dimensions can provide information regarding the ...