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Novel biotechnological platform based on baculovirus occlusion bodies carrying Babesia bovis small antigenic peptides for the design of a diagnostic enzyme-linked immunosorbent assay (ELISA)
(Springer, 2018-01)Baculoviruses are large DNA virus of insects principally employed in recombinant protein expression. Its ability to form occlusion bodies (OBs), which are composed mainly of polyhedrin protein (POLH), makes them ... -
Nucleopoliedrovirus de Spodoptera frugiperda (SfMNPV)
(Asociación Argentina de Microbiología, 2020-03)SfMNPV es una especie perteneciente a la familia Baculoviridae, un grupo de virus de insectos, principalmente lepidópteros, con genoma de ADN doble cadena, circular, superenrollado, que se encuentra empaquetado en una ... -
P26 enhances baculovirus gene delivery by modulating the mammalian antiviral response
(Springer, 2023-08)Poxins are poxviral proteins that act by degrading 2´3´-cGAMP, a key molecule of cGAS-STING axis that drives and amplifies the antiviral response. Previous works have described some poxin homologous among lepidopteran and ... -
Recombinant occlusion bodies of baculovirus as carriers of a nonstructural protein of foot-and-mouth disease virus
(Springer, 2018-11)Here, we developed a diagnostic ELISA for foot-and-mouth disease using recombinant occlusion bodies (rOBs) of baculovirus. We fused Δ3AB1–3, a polypeptide derived from non-structural proteins of foot-and-mouth disease ... -
Successful production of the potato antimicrobial peptide Snakin-1 in baculovirus-infected insect cells and development of specific antibodies
(2017)Background: Snakin-1 (StSN1) is a broad-spectrum antimicrobial cysteine-rich peptide isolated from Solanum tuberosum. Its biotechnological potential has been already recognized since it exhibits in vivo antifungal and ... -
The autographa californica multiple nucleopolyhedrovirus Ac12: A non-essential F box-like protein that interacts with cellular SKP1 component of the E3 ubiquitin ligase complex
(Elsevier, 2019-01)The Autographa californica multiple nucleopolyhedrovirus (AcMNPV) ac12 gene, which is conserved in ten other baculovirus, codes a predicted 217 amino acid protein of unknown function. In this study, we investigated the ... -
TLR9 activation is required for cytotoxic response elicited by baculovirus capsid display
(Wiley, 2023-05)Although the baculovirus Autographa californica multiple nuclear polyhedrosis virus (AcMNPV) infects lepidopteran invertebrates as natural hosts, represents an efficient vector for vaccine development. Baculovirus surface ... -
Trans-complementation of polyhedrin by a stably transformed Sf9 insect cell line allows occ− baculovirus occlusion and larval per os infectivity
(Elsevier, 2010-01-15)Oral infection of insect larvae with baculovirus is an advantageous methodology for producing high levels of recombinant proteins and for achieving plague control. However, many recombinant baculoviruses express a foreign ... -
Two distinctive phenotypes of AcMNPV display different immune abilities and intracellular destiny
(2016-12-29)The budded phenotype (BV) of the baculovirus AcMNPV has been demonstrated to have strong immunostimulatory properties that are relevant for the development of vaccines and antiviral therapies. Although the occluded ... -
Utilización regional de baculovirus en el control de plagas hortícolas
(Ediciones INTA, 2021-12)Los baculovirus son patógenos aislados de insectos, principalmente del orden Lepidoptera. Se caracterizan por su alta especificidad, pues poseen un espectro de hospedadores reducido, y por ser inocuos para artrópodos ... -
VP1 protein of Foot-and-mouth disease virus (FMDV) impairs baculovirus surface display
(Elsevier, 2013-07)The Foot-and-mouth disease virus (FMDV) causes important economical losses in livestock farming. In order to develop a novel subunit vaccine against FMDV, we constructed recombinant baculoviruses that display the protein ...