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Abstract
Spodoptera frugiperda multiple nucleopolyhedrovirus (SfMNPV) represents a strong candidate to develop environmental-friendly pesticides against the fall armyworm (Spodoptera frugiperda), a widespread pest that poses a severe threat to different crops around the world. To date, SfMNPV genomic diversity of different isolates has been mainly studied by means of restriction pattern analyses and by sequencing of the egt region. Here, the genomic diversity [ver mas...]
dc.contributor.authorMasson, Tomás
dc.contributor.authorFabre, María Laura
dc.contributor.authorPidre, Matias Luis
dc.contributor.authorNiz, José María
dc.contributor.authorBerretta, Marcelo Facundo
dc.contributor.authorRomanowski, Víctor
dc.contributor.authorFerrelli, María Leticia
dc.date.accessioned2022-07-26T22:16:56Z
dc.date.available2022-07-26T22:16:56Z
dc.date.issued2021-06
dc.identifier.otherhttps://doi.org/10.1016/j.meegid.2021.104749
dc.identifier.urihttp://hdl.handle.net/20.500.12123/12408
dc.identifier.urihttps://www.sciencedirect.com/science/article/abs/pii/S1567134821000460
dc.description.abstractSpodoptera frugiperda multiple nucleopolyhedrovirus (SfMNPV) represents a strong candidate to develop environmental-friendly pesticides against the fall armyworm (Spodoptera frugiperda), a widespread pest that poses a severe threat to different crops around the world. To date, SfMNPV genomic diversity of different isolates has been mainly studied by means of restriction pattern analyses and by sequencing of the egt region. Here, the genomic diversity present inside an isolate of SfMNPV was explored using high-throughput sequencing for the first time. We identified 704 intrahost single nucleotide variants, from which 184 are nonsynonymous mutations distributed among 82 different coding sequences. We detected several structural variants affecting SfMNPV genome, including two previously reported deletions inside the egt region. A comparative analysis between polymorphisms present in different SfMNPV isolates and our intraisolate diversity data suggests that coding regions with higher genetic diversity are associated with oral infectivity or unknown functions. In this context, through molecular evolution studies we provide evidence of diversifying selection acting on sf29, a putative collagenase which could contribute to the oral infectivity of SfMNPV. Overall, our results contribute to deepen our understanding of the coevolution between SfMNPV and the fall armyworm and will be useful to improve the applicability of this virus as a biological control agent.eng
dc.formatapplication/pdfes_AR
dc.language.isoenges_AR
dc.publisherElsevieres_AR
dc.rightsinfo:eu-repo/semantics/restrictedAccesses_AR
dc.sourceInfection, Genetics and Evolution 90 : 104749 (junio 2021)es_AR
dc.subjectSpodoptera frugiperdaes_AR
dc.subjectBiological Controleng
dc.subjectControl Biológicoes_AR
dc.subjectPlaguicidas
dc.subjectPesticideseng
dc.subject.otherBaculoviruses_AR
dc.subject.otherGenomic Diversityeng
dc.subject.otherVirus Evolutioneng
dc.subject.otherSfMNPVeng
dc.titleGenomic diversity in a population of Spodoptera frugiperda nucleopolyhedroviruses_AR
dc.typeinfo:ar-repo/semantics/artículoes_AR
dc.typeinfo:eu-repo/semantics/articlees_AR
dc.typeinfo:eu-repo/semantics/publishedVersiones_AR
dc.description.origenInstituto de Microbiología y Zoología Agrícola (IMYZA)es_AR
dc.description.filFil: Masson, Tomás. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Biotecnología y Biología Molecular (IBBM-UNLP-CONICET); Argentinaes_AR
dc.description.filFil: Fabre, María Laura. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Biotecnología y Biología Molecular (IBBM-UNLP-CONICET); Argentinaes_AR
dc.description.filFil: Pidre, Matias Luis. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Biotecnología y Biología Molecular (IBBM-UNLP-CONICET); Argentinaes_AR
dc.description.filFil: Niz, José. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Microbiología y Zoología Agrícola; Argentinaes_AR
dc.description.filFil: Berretta, Marcelo Facundo. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Microbiología y Zoología Agrícola; Argentinaes_AR
dc.description.filFil: Romanowski, Víctor. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Biotecnología y Biología Molecular (IBBM-UNLP-CONICET); Argentinaes_AR
dc.description.filFil: Ferrelli, María Leticia. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Biotecnología y Biología Molecular (IBBM-UNLP-CONICET); Argentinaes_AR
dc.subtypecientifico


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