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This paper reveals, for the first time, the functional properties of propolis from an extreme region of Argentine (El Rincón, Province of Catamarca, Argentina), as well as the isolation and identification of bioactive compounds. The antioxidant activity was determined by the ABTS method and β-carotene bleaching. The antibacterial activity was determined on methicillin resistant Staphylococcus aureus (MRSA) by the microdilution method and bioautographic
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dc.contributor.author | Vera, Nancy Roxana | |
dc.contributor.author | Solórzano, Eliana | |
dc.contributor.author | Ordóñez, Roxana Mabel | |
dc.contributor.author | Maldonado, Luis Maria | |
dc.contributor.author | Bedascarrasbure, Enrique Luciano | |
dc.contributor.author | Isla, María Inés | |
dc.coverage.spatial | Argentina .......... (nation) (World, South America) | es_AR |
dc.coverage.spatial | 7006477 | es_AR |
dc.date.accessioned | 2022-07-20T10:48:32Z | |
dc.date.available | 2022-07-20T10:48:32Z | |
dc.date.issued | 2011-06 | |
dc.identifier.issn | 1934-578X | |
dc.identifier.issn | 1555-9475 | |
dc.identifier.other | https://doi.org/10.1177/1934578X1100600618 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12123/12357 | |
dc.identifier.uri | https://journals.sagepub.com/doi/abs/10.1177/1934578X1100600618 | |
dc.description.abstract | This paper reveals, for the first time, the functional properties of propolis from an extreme region of Argentine (El Rincón, Province of Catamarca, Argentina), as well as the isolation and identification of bioactive compounds. The antioxidant activity was determined by the ABTS method and β-carotene bleaching. The antibacterial activity was determined on methicillin resistant Staphylococcus aureus (MRSA) by the microdilution method and bioautographic assays. Twelve compounds were isolated and identified by NMR spectroscopy. The main bioactive compounds were 2′,4′-dihydroxy-3′-methoxychalcone (3), 2′,4′-dihydroxychalcone (9), 2′,4′,4-trihydroxy-6′- methoxychalcone (8), 5-hydroxy-4′,7-dimethoxyflavone (4), 4′,5-dihydroxy-3,7,8-trimethoxyflavone (10) and 7-hydroxy- 5,8-dimethoxyflavone (11). All compounds were active against clinical isolates (MIC50 10 μg/ mL) and displayed antioxidant activity (SC50 values of 20 μg/mL). The MIC and SC50 values of the isolated compounds were lower than those obtained with crude propolis extracts, chloroform sub-extracts and isolated fractions. | eng |
dc.format | application/pdf | es_AR |
dc.language.iso | eng | es_AR |
dc.publisher | Sage Publishing | es_AR |
dc.rights | info:eu-repo/semantics/openAccess | es_AR |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | |
dc.source | Natural Product Communications 6 (6) : 823-827 (June 2011) | es_AR |
dc.subject | Propóleos | es_AR |
dc.subject | Propolis | eng |
dc.subject | Composición Quimica | es_AR |
dc.subject | Chemical Composition | eng |
dc.subject | Propiedades Antimicrobianas | es_AR |
dc.subject | Antimicrobial Properties | eng |
dc.subject | Propiedades Antioxidantes | es_AR |
dc.subject | Antioxidant Properties | eng |
dc.subject | Argentina | es_AR |
dc.subject | cientifico | |
dc.title | Chemical Composition of Argentinean Propolis Collected in Extreme Regions and its Relation with Antimicrobial and Antioxidant Activities | es_AR |
dc.type | info:ar-repo/semantics/artículo | es_AR |
dc.type | info:eu-repo/semantics/article | es_AR |
dc.type | info:eu-repo/semantics/publishedVersion | es_AR |
dc.rights.license | Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) | |
dc.description.origen | EEA Famaillá | es_AR |
dc.description.fil | Fil: Vera, Nancy Roxana. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; Argentina | es_AR |
dc.description.fil | Fil: Vera, Nancy Roxana. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Famaillá; Argentina | es_AR |
dc.description.fil | Fil: Solórzano, Eliana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tucumán. Instituto de Química del Noroeste; Argentina | es_AR |
dc.description.fil | Fil: Ordóñez, Roxana Mabel. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; Argentina | es_AR |
dc.description.fil | Fil: Ordóñez, Roxana Mabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tucumán. Instituto de Quimica del Noroeste; Argentina. | es_AR |
dc.description.fil | Fil: Maldonado, Luis Maria. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Famaillá; Argentina | es_AR |
dc.description.fil | Fil: Bedascarrasbure, Enrique Luciano. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Famaillá; Argentina | es_AR |
dc.description.fil | Fil: Isla, Maria Ines. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; Argentina | es_AR |
dc.description.fil | Fil: Isla, Maria Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tucumán. Instituto de Quimica del Noroeste; Argentina | es_AR |
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