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A single nanobody neutralizes multiple epochally evolving human noroviruses by modulating capsid plasticity
(Nature Publishing Group, 2023-10)Acute gastroenteritis caused by human noroviruses (HuNoVs) is a significant global health and economic burden and is without licensed vaccines or antiviral drugs. The GII.4 HuNoV causes most epidemics worldwide. This virus ... -
"Asistimos a un momento histórico de la mujer en la ciencia"
(Ediciones INTA, 2019-04)Con esta definición Viviana Parreño reconoce el lugar de las científicas como parte de un cambio en la ciencia argentina. Repasa el presente del desarrollo de nanoanticuerpos VHH de llama para prevenir el rotavirus, un ... -
Chapter 11 - Valorization of waste and by-products from food industries through the use of innovative technologies
(Elsevier, 2020-03-06)Food waste and by-products, which are normally regarded as not being valuable, have great potential for valuable compounds production. Valorization of these materials not only means more nutrients or bioactive compounds, ... -
Construyen una biblioteca de nanoanticuerpos de llamas contra la COVID-19
(Ediciones INTA, 2020-08)Se trata del primer reservorio elaborado en la Argentina y que contiene información sobre los anticuerpos que producen estos camélidos frente al SARS-CoV-2. Con la información obtenida de la biblioteca se podrán obtener ... -
Development and biological evaluation of pNIPAM-based nanogels as vaccine carriers
(Elsevier, 2023-01)“Smart” nanogels are an attractive tool for the development of new strategies of immunization in veterinary medicine. Here, we reported the synthesis and physicochemical characterization of thermoresponsive nanogels based ... -
Development of recombinant VHH nanobodies as an alternative for clearance of equine arteritis virus in carrier stallions
(2016)In conclusion, a VHH library derived from llama B cells following immunization with EAV was generated. This novel strategy could allow the generation of EAV-specific neutralizing Nbs as a therapeutic approach to induce ... -
Effects of polydopamine-passivation on the optical properties of carbon dots and its potential use in vivo
(Royal Society of Chemistry, 2020-07)Passivation of carbon dots via heteroatom doping has been shown to enhance their optical properties and tune their fluorescence signature. Additionally, the incorporation of polymeric precursors in carbon dot synthesis has ... -
Evaluation of oral supplementation of free and nanoencapsulated Minthostachys verticillata essential oil on immunological, biochemical and antioxidants parameters and gut microbiota in weaned piglets
(Springer, 2024-03)Early weaning is an important stressor that impairs the piglet´s health, and essential oils appear as promising candidates to improve it instead of antibiotics. The aim of this study was to evaluate the effect of oral ... -
Formation of dendrimer-guest complexes as a strategy to increase the solubility of a phenazine N, N′-dioxide derivative with antitumor activity
(Elsevier, 2019-04-23)Poly(amidoamine) and Poly(propylenimine) dendrimers with different generations and peripheral groups were studied as solubility enhancers and nanocarriers for 7-bromo-2-hydroxy-phenazine N5,N10-dioxide. This compound ... -
Fungicide efficacy of nanocrystal-based formulations against peanut smut
(Elsevier, 2021-03)Nanocrystal-based formulations were investigated as a novel technology to increase the fungicide efficacies of azoxystrobin (AZY), cyproconazole (CYP), and their combination (AZY + CYP) against peanut smut caused by ... -
Impacto de la nanotecnología en suelos sódicos y el crecimiento del cultivo de sorgo
(Asociación Argentina Ciencias del Suelo, 2020-05-26)Los suelos sódicos se caracterizan por tener un elevado pH 8 5 y una cantidad de sodio Na intercambiable (PSI 15 suficiente para afectar adversamente al cultivo de sorgo y la estructura del suelo. El exceso de Na en los ... -
Llamas contra el rotavirus humano
(Gerencia de Comunicación e Imagen Institucional, DNA SICC, INTA, 2012-12)Investigadores argentinos descubrieron una novedosa manera de combatir esta enfermedad diarreica que afecta principalmente a niños menores de cinco años. La presencia de anticuerpos VHH en leche de vaca se presenta como ... -
Nanostructured voltammetric sensor for ultra-trace anabolic drug determination in food safety field
(2013-11)A sensitive electrochemical sensor for clenbuterol (CL) determination in bovine urine samples was designed. This drug was originally developed for the treatment of respiratory pathologies. However, in the livestock industry, ... -
Nanotecnología aplicada a las formulaciones de fungicidas para el control del carbón del maní
(Centro de Ingenieros Agrónomos General Cabrera, 2021-09-17)El carbón del maní es la enfermedad más importante del cultivo en Argentina, en cierta medida por la baja utilización de estrategias de control, muchas veces poco eficientes o con resultados variables. La infección es ... -
Ultra sensitive microfluidic immunosensor for determination of clenbuterol in bovine hair samples using electrodeposited gold nanoparticles and magnetic micro particles as bio-affinity platform
(Elsevier, 2013-03-15)In this article, we report the first integrated microfluidic immunosensor coupled to a screen-printed carbon electrode (SPCE) applied to determination of clenbuterol (CLB) in bovine hair samples. CLB is a member of the ...