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An improved DNA vaccine against bovine herpesvirus-1 using CD40L and a chemical adjuvant induces specific cytotoxicity in mici
(Mary Ann Liebert, 2021-03)Bovine herpesvirus-1 (BoHV-1) uses many mechanisms to elude the immune system; one of them is spreading intracellularly, even in the presence of specific antiviral antibodies. Cytotoxic T lymphocytes (CTLs) are necessary ... -
Baculovirus capsid display in vaccination schemes: effect of a previous immunity against the vector on the cytotoxic response to delivered antigens
(Springer, 2018-12)The baculovirus Autographa californica multiple nuclear polyhedrosis virus (AcMNPV) infects lepidopteran invertebrates as natural hosts, although it also has been used as display vector for vaccine development. In this ... -
Cytotoxicity and bioadhesive properties of poly-N-isopropylacrylamide hydrogel
(Elsevier, 2019-04-09)Several hydrogel surfaces present properties that simulate the mechanical and physicochemical features of extracellular matrix (ECM), providing a platform that mimic the native cellular milieus. Poly-N-isopropylacrylamide ... -
Effect of Lippia alba and Cymbopogon citratus essential oils on biofilms of Streptococcus mutans and cytotoxicity in CHO cells
(Elsevier, 2016-12)Background: Caries is a public health problem, given that it prevails in 60 to 90% of the school-age global population. Multiple factors interact in its etiology, among them dental plaque is necessary to have lactic ... -
Estudio de la actividad biológica y toxicidad de extractos naturales obtenidos a partir de especies vegetales silvestres
(2018-08)El objetivo de este trabajo fue caracterizar extractos acuosos de especies vegetales silvestres en base a su capacidad antioxidante, inhibición del pardeamiento enzimático y citotoxicidad para evaluar su utilización corno ... -
Estudio de la toxicidad y actividad biológica (actividad antioxidante e inhibidora del pardeamiento enzimático) de especies silvestres
(Asociación Argentina de Tecnólogos Alimentarios, 2017-09)El objetivo de este trabajo fue caracterizar especies vegetales silvestres en base a su capacidad antioxidante, inhibitoria de la PPO y citotoxidad para evaluar su utilización como aditivo antioxidante en matrices alimentarias. ... -
Evaluation of the toxicological effects of Neltuma alpataco (Prosopis alpataco) pod alkaloid extract
(Elsevier, 2024-04)The pods of Neltuma spp. have shown potential as a source of protein and energy in livestock. However, prolonged consumption of some of these species can lead to neurological symptoms in ruminants. This study aimed to ... -
Foot-and-mouth disease virus infection of dendritic cells triggers phosphorylation of ERK1/2 inducing class I presentation and apoptosis
(Elsevier, 2015-09)Foot-and-mouth disease (FMD) is a highly contagious viral disease of cloven-hoofed animals. This pathology is caused by foot-and-mouth disease virus (FMDV). Over time, the development of vaccines to prevent the spread of ... -
Formation of dendrimer-guest complexes as a strategy to increase the solubility of a phenazine N, N′-dioxide derivative with antitumor activity
(Elsevier, 2019-04-23)Poly(amidoamine) and Poly(propylenimine) dendrimers with different generations and peripheral groups were studied as solubility enhancers and nanocarriers for 7-bromo-2-hydroxy-phenazine N5,N10-dioxide. This compound ... -
TLR9 activation is required for cytotoxic response elicited by baculovirus capsid display
(Wiley, 2023-05)Although the baculovirus Autographa californica multiple nuclear polyhedrosis virus (AcMNPV) infects lepidopteran invertebrates as natural hosts, represents an efficient vector for vaccine development. Baculovirus surface ...