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Resumen
Bovine leukemia virus (BLV) is a retrovirus that affects cattle causing a lymphoproliferative disease. BLV infection has been associated with misbalance of the immune response causing a higher incidence of other infections. Mastitis is one of the most important conditions that affect milk production in cattle. The aim of this study was to stably infect a bovine mammary epithelial cell line (MAC-T). MAC-T cell line was successfully infected with BLV and
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| dc.contributor.author | Martinez Cuesta, Lucia | |
| dc.contributor.author | Lendez, Pamela Anahi | |
| dc.contributor.author | Barone, Lucas | |
| dc.contributor.author | Perez, Sandra Elizabeth | |
| dc.contributor.author | Dolcini, Guillermina Laura | |
| dc.contributor.author | Ceriani, Maria Carolina | |
| dc.contributor.author | Nieto Farias, Maria Victoria | |
| dc.date.accessioned | 2019-12-12T14:45:07Z | |
| dc.date.available | 2019-12-12T14:45:07Z | |
| dc.date.issued | 2018 | |
| dc.identifier.issn | 0168-1702 | |
| dc.identifier.other | https://doi.org/10.1016/j.virusres.2018.07.013 | |
| dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S0168170218302508 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.12123/6496 | |
| dc.description.abstract | Bovine leukemia virus (BLV) is a retrovirus that affects cattle causing a lymphoproliferative disease. BLV infection has been associated with misbalance of the immune response causing a higher incidence of other infections. Mastitis is one of the most important conditions that affect milk production in cattle. The aim of this study was to stably infect a bovine mammary epithelial cell line (MAC-T). MAC-T cell line was successfully infected with BLV and the infection was confirmed by nested PCR, qPCR, immunocytochemistry, western blot and transmission electron microscopy. This is the first report of a bovine mammary epithelial cell line stably infected with BLV. This new cell line could be used as an in vitro model to study the effect of BLV on the immune response in the mammary gland and the relationship with other agents causing mastitis. | eng |
| dc.format | application/pdf | es_AR |
| dc.language.iso | eng | es_AR |
| dc.publisher | Elsevier | es_AR |
| dc.rights | info:eu-repo/semantics/restrictedAccess | es_AR |
| dc.source | Volume 256 : 11-16 (September 2018) | es_AR |
| dc.subject | Bovine Leukaemia Virus | eng |
| dc.subject | Virus Leucemia Bovina | es_AR |
| dc.subject | Mmastitis | es_AR |
| dc.subject | Infection | eng |
| dc.subject | infección | es_AR |
| dc.subject.other | MAC-T | es_AR |
| dc.title | Stable infection of a bovine mammary epithelial cell line (MAC-T) with bovine leukemia virus (BLV) | es_AR |
| dc.type | info:ar-repo/semantics/artículo | es_AR |
| dc.type | info:eu-repo/semantics/article | es_AR |
| dc.type | info:eu-repo/semantics/publishedVersion | es_AR |
| dc.description.origen | Instituto de Virología | es_AR |
| dc.description.fil | Fil: Martinez Cuesta, Lucia. Consejo Nacional de Investigaciones Cientificas y Tecnicas (Conicet). Centro de Investigación Veterinaria de Tandil. Laboratorio de Virología. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Centro de Investigación Veterinaria de Tandil (CIVETAN); Argentina | es_AR |
| dc.description.fil | Fil: Lendez, Pamela Anahi. Consejo Nacional de Investigaciones Cientificas y Tecnicas (Conicet). Centro de Investigación Veterinaria de Tandil. Laboratorio de Virología. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Centro de Investigación Veterinaria de Tandil (CIVETAN); Argentina | es_AR |
| dc.description.fil | Fil: Barone, Lucas. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina | es_AR |
| dc.description.fil | Fil: Pérez, Sandra Elizabeth. Consejo Nacional de Investigaciones Cientificas y Tecnicas (Conicet). Centro de Investigación Veterinaria de Tandil. Laboratorio de Virología. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Centro de Investigación Veterinaria de Tandil (CIVETAN); Argentina | es_AR |
| dc.description.fil | Fil: Dolcini, Guillermina Laura. Consejo Nacional de Investigaciones Cientificas y Tecnicas (Conicet). Centro de Investigación Veterinaria de Tandil. Laboratorio de Virología. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Centro de Investigación Veterinaria de Tandil (CIVETAN); Argentina | es_AR |
| dc.description.fil | Fil: Ceriani, Maria Carolina. Consejo Nacional de Investigaciones Cientificas y Tecnicas (Conicet). Centro de Investigación Veterinaria de Tandil. Laboratorio de Virología. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Centro de Investigación Veterinaria de Tandil (CIVETAN); Argentina | es_AR |
| dc.description.fil | Fil: Nieto Farias, Maria Victoria. Consejo Nacional de Investigaciones Cientificas y Tecnicas (Conicet). Centro de Investigación Veterinaria de Tandil. Laboratorio de Virología. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Centro de Investigación Veterinaria de Tandil (CIVETAN); Argentina | es_AR |
| dc.subtype | cientifico |
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