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Mostrando ítems 1-8 de 8
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Association of an IRF3 putative functional uORF variant with resistance to Brucella infection: A candidate gene based analysis of InDel polymorphisms in goats
Rossi, Ursula; Hasenauer, Flavia Carolina; Caffaro, María Eugenia; Raschia, Maria Agustina; Maurizio, Estefania; Cortez, Hector Sergio; Neumann, Roberto Daniel; Poli, Mario Andres; Rossetti, Carlos Alberto (Elsevier, 2019-03)Brucellosis is an important zoonotic disease caused by infection with Brucella spp. It generates major economic losses in livestock production worldwide. Goats are the principal hosts of B. melitensis, the main infection ... -
Association of TNF rs668920841 and INRA111 polymorphisms with caprine brucellosis: A case-control study of candidate genes involved in innate immunity
Hasenauer, Flavia Carolina; Rossi, Ursula; Caffaro, María Eugenia; Raschia, Maria Agustina; Maurizio, Estefanía; Poli, Mario Andres; Rossetti, Carlos Alberto (Elsevier, 2020-11)Caprine brucellosis is an infectious, contagious zoonotic disease caused by Brucella melitensis. Multiple factors, including host genetics, can influence the outcome of the exposure to Brucella; and it is expected that ... -
Deletion in KARLN intron 5 and predictive relationship with bovine tuberculosis and brucellosis infection phenotype
Rossi, Ursula Amaranta; Caffaro, María Eugenia; Raschia, Maria Agustina; Hasenauer, Flavia Carolina; Poli, Mario Andres; Rossetti, Carlos Alberto (Springer, 2023-06)Kalirin (gene: KALRN) is a Rho-GEF kinase linked to neurodegenerative diseases in humans. Unexpectedly, various polymorphisms in KALRN gene were previously associated with resistance to bacterial infections in ruminants. ... -
Evaluation of polymorphisms at the 3´ UTR SLC11A1 gene microsatellites and their associations with the outcome of Brucella abortus infection in Bos taurus cattle
Hasenauer, Flavia Carolina; Caffaro, María Eugenia; Poli, Mario Andres; Rossetti, Carlos Alberto (Ediciones INTA, 2022-11)In ruminants, polymorphisms in microsatellites at 3´untranslated region (3´ UTR) of the SLC11A1 gene were associated with natural resistance to Brucella spp. and Mycobacterium spp. infection, but its relevance to prevent ... -
Exploring the association between polymorphisms at 3’UTR SLC11A1 gene microsatellites and resistance to tuberculosis: A case-control study in Bos taurus dairy cattle
Hasenauer, Flavia Carolina; Garbaccio, Sergio Gabriel; Caffaro, María Eugenia; Garro, Carlos Javier; Huertas, Pablo Sebastian; Poli, Mario Andres; Rossetti, Carlos Alberto (2018-04)Bovine tuberculosis is a contagious infectious disease that causes significant economic impact in dairy and meat farms throughout the world. Multiple factors, including host genome, determine the outcome of the infection. ... -
Genetic analysis of the 3′ untranslated region of the bovine SLC11A1 gene reveals novel polymorphisms
Hasenauer, Flavia Carolina; Caffaro, María Eugenia; Czibener, Cecilia; Comerci, Diego José; Poli, Mario Andres; Rossetti, Carlos Alberto (Springer, 2013-01)Polymorphisms in microsatellites at the 3′ untranslated region (3′UTR) of the SLC11A1 (solute carrier family 11 member A1) gene have been associated with natural resistance to Brucella abortus and Mycobacterium bovis ... -
A haplotype at intron 8 of PTPRT gene is associated with resistance to Brucella infection in Argentinian creole goats
Rossi, Ursula; Hasenauer, Flavia Carolina; Caffaro, María Eugenia; Neumann, Roberto Daniel; Salatin, Antonio Omar; Poli, Mario Andres; Rossetti, Carlos Alberto (2017-08)Brucellosis is the leading zoonosis on a worldwide scale and constitutes a major public health threat in many regions of the world. Several molecular markers associated with natural resistance to intracellular bacterial ... -
Polymorphisms at the 3′ untranslated region of SLC11A1 gene are associated with protection to Brucella infection in goats
Iacoboni, Paola Anabella; Hasenauer, Flavia Carolina; Caffaro, María Eugenia; Gaido, Analia Beatriz; Rossetto, Cristina; Neumann, Roberto Daniel; Salatin, Antonio Omar; Bertoni, Emiliano Agustín; Poli, Mario Andres; Rossetti, Carlos Alberto (Elsevier, 2014-08-15)Goats are susceptible to brucellosis and the detection of Brucella-infected animals is carried out by serological tests. In other ruminant species, polymorphisms in microsatellites (Ms) of 3′ untranslated region (3′UTR) ...