• Anthropogenic infection of domestic cats with SARS-CoV-2 alpha variant B.1.1.7 lineage in Buenos Aires 

      Pecora, Andrea; Malacari, Darío Amilcar; Mozgovoj, Marina Valeria; Díaz, María de los Ángeles; Peralta, Andrea Veronica; Cacciabue, Marco Polo Domingo; Puebla, Andrea Fabiana; Carusso, Cristian; Mundo, Silvia Leonor; Gonzalez Lopez Ledesma, María Mora; Gamarnik, Andrea Vanesa; Rinaldi, Osvaldo; Vidal, Osvaldo; Mas, Javier; Dus Santos, Maria Jose (Frontiers Media, 2022-03)
      SARS-CoV-2 reverse zoonosis, particularly to domestic animals, and the potential role of infected animals in perpetuating the spread of the virus is an issue of increasing concern. In this case report, we identified the ...
    • Development of nanobody-displayed whole-cell biosensors for the colorimetric detection of SARS-CoV‑2 

      He, Yawen; Xu, Zhiyuan; Kasputis, Tom; Zhao, Xue; Ibañez, Itati; Pavan, Florencia; Bok, Marina; Malito, Juan Pablo; Parreño, Gladys Viviana; Yuan, Lijuan; Wright, R. Clay; Chen, Juhong (American Chemical Society, 2023-08)
      The accurate and effective detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is essential to preventing the spread of infectious diseases and ensuring human health. Herein, a nanobody-displayed ...
    • Evaluation of a lyophilized CRISPR-Cas12 assay for a sensitive, specific, and rapid detection of SARS-CoV-2 

      Curti, Lucía Ana; Primost, Ivana; Valla, Sofia; Ibañez Alegre, Daiana; Olguin Perglione, Cecilia; Repizo, Guillermo Daniel; Lara, Julia; Parcerisa, Ivana; Palacios, Antonela; Llases, María Eugenia; Rinflerch, Adriana; Barrios, Melanie; Pereyra Bonnet, Federico; Gimenez, Carla Alejandra; Marcone, Débora Natalia (MDPI, 2021-03)
      We evaluated a lyophilized CRISPR-Cas12 assay for SARS-CoV-2 detection (Lyo-CRISPR SARS-CoV-2 kit) based on reverse transcription, isothermal amplification, and CRISPR-Cas12 reaction. From a total of 210 RNA samples extracted ...
    • SARS-CoV-2 specific nanobodies neutralize different variants of concern and reduce virus load in the brain of h-ACE2 transgenic mice 

      Pavan, Florencia; Bok, Marina; Betanzos San Juan, Rafael; Malito, Juan Pablo; Marcoppido, Gisela Ariana; Franco, Diego Rafael; Militelo, Daniela Ayelen; Schammas, Juan Manuel; Bari, Sara Elizabeth; Stone, William B.; López, Krisangel; Porier, Danielle LaBrie; Muller, John Anthony; Auguste, Albert J.; Yuan, Lijuan; Wigdorovitz, Andres; Parreño, Gladys Viviana; Ibañez, Lorena Itat (MDPI, 2024-02)
      Since the beginning of the COVID-19 pandemic, there has been a significant need to develop antivirals and vaccines to combat the disease. In this work, we developed llama-derived nanobodies (Nbs) directed against the ...
    • Serological screening of SARS-CoV-2 infection in companion animals of Buenos Aires suburbs 

      Cardoso, Nancy; Rivero, Carla; Castillo, Mariangeles; Mansilla, Florencia Celeste; Pastorino, Florencia; Piccirilli, Guadalupe; Alonso, Laura; Martinez, Gustavo; Di Lullo, David; Bentancor, Leticia Veronica; Capozzo, Alejandra (Frontiers Media, 2023-05)
      The Coronavirus Disease 2019 (COVID-19) is a zoonotic disease caused by the pandemic virus SARS-CoV-2. Domestic and wild animals are susceptible to infection and are potential reservoirs for virus variants. To date, there ...