• A single nanobody neutralizes multiple epochally evolving human noroviruses by modulating capsid plasticity 

      Salmen, Wilhelm; Hu, Liya; Bok, Marina; Chaimongkol, Natthawan; Ettayebi, Khalil; Sosnovtsev, Stanislav V.; Soni, Kaundal; Ayyar, B. Vijayalakshmi; Shanker, Sreejesh; Neill, Frederick H.; Sankaran, Banumathi; Atmar, Robert L.; Estes, Mary K.; Green, Kim Y.; Parreño, Gladys Viviana; Prasad, B. V. Venkataram (Nature Publishing Group, 2023-10)
      Acute gastroenteritis caused by human noroviruses (HuNoVs) is a significant global health and economic burden and is without licensed vaccines or antiviral drugs. The GII.4 HuNoV causes most epidemics worldwide. This virus ...
    • Bovine colostral cells—the often forgotten component of colostrum 

      Gonzalez, Diego; Dus Santos, Maria Jose (American Veterinary Medical Association, 2017-05)
      At birth, neonatal calves have all the essential immune components they need as adult cattle; however, it takes at least 2 to 4 weeks for those components to become fully functional.1,2 The immune system does not become ...
    • Immune response and protection provided by live tachyzoites and native antigens from the NC-6 Argentina strain of Neospora caninum in pregnant heifers 

      Hecker, Yanina Paola; Moore, Prando Dadin; Quattrocchi, Valeria; Regidor-Cerrillo, Javier; Verna, Andrea Elizabeth; Leunda, Maria Rosa; Morrell, Eleonora Lidia; Ortega-Mora, Luis M.; Zamorano, Patricia Ines; Venturini, María Cecilia; Campero, Carlos Manuel (Elsevier, 2013-11)
      The aim of the present study was to compare the immunogenicity and protective efficacy of live tachyzoites and native antigen extract obtained from the NC-6 Argentina strain against vertical transmission of Neospora caninum, ...
    • Molecular engineering improves antigen quality and enables integrated manufacturing of a trivalent subunit vaccine candidate for rotavirus 

      Dalvie, Neil C.; Brady, Joseph R.; Crowell, Laura E.; Tracey, Mary Kate; Biedermann, Andrew M.; Kaur, Kawaljit; Hickey, John M.; Kristensen II, D. Lee; Bonnyman, Alexandra D.; Rodriguez-Aponte, Sergio A.; Whittaker, Charles A.; Bok, Marina; Vega, Celina Guadalupe; Mukhopadhyay, Tarit K.; Joshi, Sangeeta B.; Volkin, David B.; Parreño, Gladys; Love, Kerry R.; Love, J. Christopher (BMC, 2021-05)
      Background: Vaccines comprising recombinant subunit proteins are well-suited to low-cost and high-volume production for global use. The design of manufacturing processes to produce subunit vaccines depends, however, on the ...