autores
- xmlui.general.dspace_homeCentros e Institutos de InvestigaciónCICVyA. Centro de Investigación en Ciencias Veterinarias y AgronómicasInstituto de BiotecnologíaArtículos científicosxmlui.ArtifactBrowser.ConfigurableBrowse.trail.metadata.authorArtículos científicos
- Inicio
- Centros e Institutos de Investigación
- CICVyA. Centro de Investigación en Ciencias Veterinarias y Agronómicas
- Instituto de Biotecnología
- Artículos científicos
- autores
Autores
Mostrando ítems 1-20 de 30
-
A β-Hairpin Motif in the Envelope Protein E2 Mediates Receptor Binding of Bovine Viral Diarrhea Virus
Merwaiss, Fernando; Pascual, María José; Pomilio, María Trinidad; Lopez, Maria Gabriela; Taboga, Oscar Alberto; Alvarez, Diego Ezequiel (MDPI, 2021-06)Pestivirus envelope protein E2 is crucial to virus infection and accomplishes virus-receptor interaction during entry. However, mapping of E2 residues mediating these interactions has remained unexplored. In this study, ... -
AcMNPV Core Gene ac109 Is Required for Budded Virion Transport to the Nucleus and for Occlusion of Viral Progeny
Alfonso, Victoria; Maroniche, Guillermo Andrés; Reca, Sol Rita; Lopez, Maria Gabriela; Del Vas, Mariana; Taboga, Oscar Alberto (Plos One, 2012-09)The Autographa californica multiple nucleopolyhedrovirus (AcMNPV) ac109 core gene has been previously characterized as an essential late gene. Our results showed that budded virions could be detected in supernatants of ... -
Allelic differences in a vacuolar invertase affect Arabidopsis growth at early plant development
Coluccio Leskow, Carla; Dominguez, Pia Guadalupe; Díaz Zirpolo, José Antonio; Obata, Toshihiro; Kamenetzky, Laura; Costa, Hernán; Taboga, Oscar Alberto; Marti, Hector Ruben; Keurentjes, Joost; Sulpice, Ronan; Ishihara, Hirofumi; Stitt, Mark; Fernie, Alisdair R.; Carrari, Fernando (2016)Improving carbon fixation in order to enhance crop yield is a major goal in plant sciences. By quantitative trait locus (QTL) mapping, it has been demonstrated that a vacuolar invertase (vac-Inv) plays a key role in ... -
Antiviral efficacy of short-hairpin RNAs and artificial microRNAs targeting foot and-mouth disease virus
Curra, Anabella Paola; Cacciabue, Marco Polo Domingo; Gravisaco, María José; Asurmendi, Sebastian; Taboga, Oscar Alberto; Gismondi, Maria Ines (Peer J Inc., 2021-06)RNA interference (RNAi) is a well-conserved mechanism in eukaryotic cells that directs post-transcriptional gene silencing through small RNA molecules. RNAi has been proposed as an alternative approach for rapid and specific ... -
Artificial microRNAs as antiviral strategy to FMDV: structural implications of target selection
Gismondi, Maria Ines; Ortiz, Xoana P.; Curra, Anabella Paola; Asurmendi, Sebastian; Taboga, Oscar Alberto (2014-04)RNA interference (RNAi) appears as a promising strategy to control virus replication. While the antiviral power of short-hairpin RNAs or small-interfering RNAs against FMDV has been demonstrated widely, safer RNAi effectors ... -
Baculovirus AcMNPV induces type I interferons and NK/NKT cells-mediated protection against foot-and-mouth disease virus in mice
Molina, Guido Nicolas; Cacciabue, Marco Polo; Gismondi, Maria Ines; Taboga, Oscar Alberto; Molinari, Maria Paula (Elsevier, 2020-08)Foot-and-mouth disease is a viral illness that affects cloven-hoofed animals causing serious economic losses. Inactivated vaccines against its causative agent, foot-and-mouth disease virus (FMDV), require approximately ... -
Baculovirus capsid display in vaccination schemes: effect of a previous immunity against the vector on the cytotoxic response to delivered antigens
Molinari, Maria Paula; Molina, Guido Nicolás; Tavarone, Maria Eugenia; Del Medico Zajac, Maria Paula; Moron, Victor Gabriel; Taboga, Oscar Alberto (Springer, 2018-12)The baculovirus Autographa californica multiple nuclear polyhedrosis virus (AcMNPV) infects lepidopteran invertebrates as natural hosts, although it also has been used as display vector for vaccine development. In this ... -
Baculovirus transduction in mammalian cells is affected by the production of type I and III interferons, which is mediated mainly by the cGAS-STING pathway
Amalfi, Sabrina; Molina, Guido Nicolas; Bevacqua, Romina Jimena; Lopez, Maria Gabriela; Taboga, Oscar Alberto; Alfonso, Victoria (American Society for Microbiology, 2020-11)The baculovirus Autographa californica multiple nucleopolyhedrovirus is an insect virus with a circular double-stranded DNA genome, which, among other multiple biotechnological applications, is used as an expression vector ... -
Baculovirus vectors induce the production of interferons in swine : their potential in the development of antiviral strategies
Molina, Guido Nicolas; Amalfi, Sabrina; Otero, Ignacio; Taboga, Oscar Alberto; Molinari, Maria Paula (MDPI, 2021-11)The huge variety of viruses affecting swine represents a global threat. Since vaccines against highly contagious viruses last several days to induce protective immune responses, antiviral strategies for rapid control of ... -
Biotechnological applications of occlusion bodies of Baculoviruses
Lopez, Maria Gabriela; Diez, Michay; Alfonso, Victoria; Taboga, Oscar Alberto (Springer, 2018-08)The ability of Baculoviruses to hyper-express very late genes as polyhedrin, the major component of occlusion bodies (OBs) or polyhedra, has allowed the evolution of a system of great utility for biotechnology. The main ... -
Comparison of internal process control viruses for detection of food and waterborne viruses
Blanco Fernández, María Dolores; Barrios, Melina Elizabeth; Cammarata, Robertina Viviana; Torres, Carolina; Taboga, Oscar Alberto; Mbayed, Viviana Andrea (2017-05)Enteric viruses are pathogens associated with foodand waterborne outbreaks. The recovery of viruses from food or water samples is affected by the procedures applied to detect and concentrate them. The incorporation of an ... -
Development of a novel set of Gateway-compatible vectors for live imaging in insect cells
Maroniche, Guillermo Andrés; Mongelli, Vanesa Claudia; Alfonso, Victoria; Llauger, Gabriela; Taboga, Oscar Alberto; Del Vas, Mariana (The Royal Entomological Society, 2011-10)Insect genomics is a growing area of research. To exploit fully the genomic data that are being generated, high-throughput systems for the functional characterization of insect proteins and their interactomes are required. ... -
Double-layered rotavirus-like particles are efficient carriers to elicit strong CTL responses to delivered heterologous antigens
Molinari, Maria Paula; Peralta, Andrea Veronica; Maletto, Belkys Angélica; Pistoresi Palencia, Maria Cristina; Crespo, Maria Ines; Moron, Victor Gabriel; Taboga, Oscar Alberto (Elsevier, 2014-11)The first 92 amino acids of VP2 of rotavirus are dispensable for VLP assembly and can be replaced by heterologous reporter proteins without affecting either self-assembly of chimeric VP2 or the interaction with VP6 to ... -
Effects of deletion of the ac109 gene of Autographa californica nucleopolyhedrovirus on interactions with mammalian cells
Alfonso, Victoria; Amalfi, Sabrina; Lopez, Maria Gabriela; Taboga, Oscar Alberto (2017-03)Baculoviruses are able to enter into mammalian cells, where they can express a transgene that is placed under an appropriate promoter, without producing infectious progeny. ORF109 encodes an essential baculovirus protein ... -
Efficient edition of the bovine PRNP prion gene in somatic cells and IVF embryos using the CRISPR/Cas9 system
Bevacqua, Romina Jimena; Fernandez-Martín, R.; Savy, Virginia; Canel, Natalia Gabriela; Gismondi, Maria Ines; Kues, Wilfried A.; Carlson, Daniel F.; Fahrenkrug, S.C.; Niemann, H.; Taboga, Oscar Alberto; Ferraris, Sergio; Salamone, Daniel Felipe (2016-11)The recently developed engineered nucleases, such as zinc-finger nucleases, transcription activator-like effector nucleases, and clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated nuclease ... -
Functional and biochemical properties of Mal de Río Cuarto virus (Fijivirus, Reoviridae) P9-1 viroplasm protein show further similarities to animal reovirus counterparts
Maroniche, Guillermo Andrés; Mongelli, Vanesa Claudia; Peralta, Andrea Veronica; Distefano, Ana Julia; Llauger, Gabriela; Taboga, Oscar Alberto; Hopp, Horacio Esteban; Del Vas, Mariana (Elsevier, 2010-09)Mal de Río Cuarto virus (MRCV) is a plant virus of the genus Fijivirus within the family Reoviridae that infects several monocotyledonous species and is transmitted by planthoppers in a persistent and propagative manner. ... -
In vivo subcellular localization of Mal de Río Cuarto virus (MRCV) non-structural proteins in insect cells reveals their putative functions
Maroniche, Guillermo Andrés; Mongelli, Vanesa Claudia; Llauger, Gabriela; Alfonso, Victoria; Taboga, Oscar Alberto; Del Vas, Mariana (Elsevier, 2012-09)The in vivo subcellular localization of Mal de Río Cuarto virus (MRCV, Fijivirus, Reoviridae) non-structural proteins fused to GFP was analyzed by confocal microscopy. P5-1 showed a cytoplasmic vesicular-like distribution ... -
The localization of a heterologous displayed antigen in the baculovirus-budded virion determines the type and strength of induced adaptive immune response
Tavarone, Maria Eugenia; Molina, Guido Nicolas; Amalfi, Sabrina; Peralta, Andrea Veronica; Molinari, Maria Paula; Taboga, Oscar Alberto; Diaz, Silvio Ricardo; Gravisaco, María José (2017-05)In the search of strategies of presentation of heterologous antigens to elicit humoral or cellular immune responses that modulate and properly potentiate each type of response, researchers have been studying baculovirus ... -
Molecular identification of a cyclodextrin glycosyltransferase-producing microorganism and phylogenetic assessment of enzymatic activities
Caminata Landriel, Soledad; Castillo, Julieta D. L. M.; Taboga, Oscar Alberto; Ferrarotti, Susana Alicia; Gottlieb, Alexandra Marina; Costa, Hernán (Academia Brasileira de Ciências, 2019-10)Cyclodextrin glycosyltransferases (CGTases) are important enzymes in the biotechnology field because they catalyze starch conversion into cyclodextrins and linear oligosaccharides, which are used in food, pharmaceutical ... -
Novel biotechnological platform based on baculovirus occlusion bodies carrying Babesia bovis small antigenic peptides for the design of a diagnostic enzyme-linked immunosorbent assay (ELISA)
Lopez, Maria Gabriela; Pallares, H.M.; Alfonso, Victoria; Carmona, S. J.; Farber, Marisa Diana; Taboga, Oscar Alberto; Wilkowsky, Silvina Elizabeth (Springer, 2018-01)Baculoviruses are large DNA virus of insects principally employed in recombinant protein expression. Its ability to form occlusion bodies (OBs), which are composed mainly of polyhedrin protein (POLH), makes them ...