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    • Patterns and processes of mycobacterium bovis evolution revealed by phylogenomic analyses 

      Patané, José S.L.; Martins Jr, Joaquim; Castelão, Ana Beatriz C.; Nishibe, Christiane; Montera, Luciana; Bigi, Fabiana; Zumarraga, Martin Jose; Cataldi, Angel Adrian; Fonseca Junior, Antônio; Roxo, Eliana; Osório, Ana Luiza Alves Rosa; Jorge, Klaudia dos Santos Goncalves; Thacker, Tyler C.; Almeida, Nalvo Franco; Araujo, Flabio Ribeiro de; Setubal, Joâo C. (Oxford University Press, 2017-03)
      Mycobacterium bovis is an important animal pathogen worldwide that parasitizes wild and domesticated vertebrate livestock as well as humans. A comparison of the five M. bovis complete genomes from the United Kingdom, South ...

    • Polymorphisms of 20 regulatory proteins between Mycobacterium tuberculosis and Mycobacterium bovis 

      Bigi, María Mercedes; Blanco, Federico Carlos; Araujo, Flabio Ribeiro de; Thacker, Tyler C.; Zumarraga, Martin Jose; Cataldi, Angel Adrian; Soria, Marcelo Abel; Bigi, Fabiana (2016)
      Mycobacterium tuberculosis and Mycobacterium bovis are responsible for tuberculosis in humans and animals, respectively. Both species are closely related and belong to the Mycobacterium tuberculosis complex (MTC). M. ...

    • Preparation of a working seed lot of BCG and quality control by PCR genotyping 

      Trovero, A.; Argüelles, Claudia; Cataldi, Angel Adrian (Asociación Argentina de Microbiología, 2010-04)
      The bacillus Calmette-Guérin (BCG) was obtained in 1920 after successive passages leading to the attenuation of a Mycobacterium bovis strain. For the following 40 years, BCG had been replicated, resulting in substrains ...

    • Purification and characterization of a GH43 β-xylosidase from Enterobacter sp. identified and cloned from forest soil bacteria 

      Campos, Eleonora; Negro Alvarez, María José; Sabaris Di Lorenzo, Gonzalo Julián; Gonzalez, Sergio Alberto; Rorig, Marcela Laura; Talia, Paola Mónica; Grasso, Daniel Horacio; Sáez, Felicia; Manzanares Secades, Paloma; Ballesteros Perdices, Mercedes; Cataldi, Angel Adrian (Elsevier, 2014-03)
      The use of lignocellulosic biomass for second generation biofuels requires optimization of enzymatic breakdown of plant cell walls. In this work, cellulolytic bacteria were isolated from a native and two cultivated forest ...

    • Replication and transmission features of two experimental vaccine candidates against bovine tuberculosis subcutaneously administrated in a murine model 

      Ferrara Muñiz, Ximena; Garcia, Elizabeth Andrea; Blanco, Federico Carlos; Bigi, Fabiana; Zumarraga, Martin Jose; Cataldi, Angel Adrian; Eirin, Maria Emilia (Elsevier, 2022-05)
      Cattle vaccination is an attractive approach in compliance with control and eradication programs against Bovine Tuberculosis (bTB). Today, there is no anti bTB vaccine licensed. Two vaccine candidates, MbΔmce2 and MbΔmce2-phoP ...

    • Respuesta inmune en terneros experimentalmente infectados con diferentes dosis de Mycobacterium bovis 

      Blanco, Federico Carlos; Bianco, María Veronica; Meikle, Virginia; Garbaccio, Sergio Gabriel; Vagnoni, Lucas Emilio; Cataldi, Angel Adrian; Bigi, Fabiana (Gerencia de Comunicación e Imagen Institucional, DNA SICC, INTA, 2011-08)
      La tuberculosis bovina es una enfermedad zoonótica producida por Mycobacterium bovis que afecta a animales de producción causando pérdidas económicas y representa, además, un problema para la salud pública. El conocimiento ...

    • The role of glucose in the pathology of EHEC O157: H7 

      Marques Da Silva, Wanderson; Taibo, Catalina Beatriz; Sabio Y Garcia, Julia Veronica; Larzabal, Mariano; Cataldi, Angel Adrian (Cambridge University Press, 2020-04)
      The pathogen enterohemorrhagic Escherichia coli (EHEC) O157: H7 is responsible for hemorrhagic colitis and hemolytic uremic syndrome in humans [1]. During the colonization process in the gastrointestinal tract, EHEC needs ...

    • Tuberculosis in swine co-infected with Mycobacterium avium subsp. hominissuis and Mycobacterium bovis in a cluster from Argentina 

      Barandiaran, Soledad; Pérez, Andrés M.; Gioffre, Andrea; Martinez Vivot, Marcela; Cataldi, Angel Adrian; Zumarraga, Martin Jose (Cambridge University Press, 2015-04)
      In Argentina little is known about the epidemiology of tuberculosis (TB) infection in swine. We characterized the epidemiological dynamics of Mycobacterium avium complex (MAC) infection in a swine population of Argentina ...

    • Type VI secretion system in pathogenic escherichia coli: structure, role in virulence, and acquisition 

      Navarro-García, Fernando; Ruiz-Perez, Fernando; Cataldi, Angel Adrian; Larzabal, Mariano (Frontiers Media, 2019-08)
      Bacterial pathogens utilize a myriad of mechanisms to invade mammalian hosts, damage tissue sites, and evade the immune system. One essential strategy of Gram-negative bacteria is the secretion of virulence factors through ...

    • Understanding the relationship between Mycobacterium bovis spoligotypes from cattle in Latin American Countries 

      Zumarraga, Martin Jose; Arriaga, Camila; Barandiaran, Soledad; Cobos-Marín, Laura; de Waard, Jacobus; Estrada-Garcia, Iris; Figueiredo, Telma; Figueroa, Alvaro; Gimenez, Francisco; Gomes, Harrison M.; Gonzalez-y-Merchand, Jorge A.; Macías, Analía; Milián-Suazo, Feliciano; Rodríguez, Cesar Alejandro Rosales; Santillán, Marco Antonio; Suffys, Philip Noel; Trangoni, Marcos David; Zarraga, Ana Maria; Cataldi, Angel Adrian (Elsevier, 2013-02)
      Spoligotyping is the most frequently used method for genotyping isolates of Mycobacterium bovis worldwide. In the current work, we compared spoligotypes from 1684 M. bovis isolates from Argentina (816), Brazil (412), Chile ...

    • Use of touch-down polymerase chain reaction to enhance the sensitivity of Mycobacterium bovis detection 

      Zumarraga, Martin Jose; Meikle, Virginia; Bernardelli, Amelia; Abdala, Alejandro Ariel; Tarabla, Hector Dante; Romano, Maria Isabel; Cataldi, Angel Adrian (Sage Publications, 2005-05)
      The confirmatory diagnosis of Mycobacterium bovis (M. bovis) in animal samples is carried out by culture in Stonebrink media. However, culture is very slow because of the extremely long duplication time of the bacillus and ...

    • Virulence factors of the Mycobacterium tuberculosis complex 

      Forrellad, Marina Andrea; Klepp, Laura Ines; Gioffre, Andrea; Sabio y Garcia, Julia Veronica; Morbidoni, Hector R.; Santangelo, María De La Paz; Cataldi, Angel Adrian; Bigi, Fabiana (Taylor & Francis, 2013-01)
      The Mycobacterium tuberculosis complex (MTBC) consists of closely related species that cause tuberculosis in both humans and animals. This illness, still today, remains to be one of the leading causes of morbidity and ...