autores
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Autores
Mostrando ítems 1-7 de 7
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Assessment of the potential utility of different regions of Streptococcus uberis adhesion molecule (SUAM) for mastitis subunit vaccine development
Perrig, Melina Soledad; Veaute, Carolina Melania Isabel; Renna, María Sol; Pujato, Nazarena; Calvinho, Luis Fernando; Marcipar, Ivan Sergio; Barbagelata, Maria Sol (2017-04)Streptococcus uberis is one of the most prevalent pathogens causing clinical and subclinical mastitis worldwide. Among bacterial factors involved in intramammary infections caused by this organism, S. uberis adhesion ... -
Development and assessment of a new cage‐like particle adjuvant
Bertona, Daiana; Pujato, Nazarena; Bontempi, Iván; González, Verónica Doris Guadalupe; Cabrera, Gabriel Gustavo; Gugliotta, Luis Marcelino; Hozbor, Daniela Flavia; Nicastro, Alcides; Calvinho, Luis Fernando; Marcipar, Iván Sergio (2017-10)Objectives: To obtain and assess stable cage‐like particles with low surface charge density, which can be prepared using a standardized, economic and scalable method. Methods: To form these nanoparticles, the lipid ... -
Evaluation of the humoral immune response to a multicomponent recombinant vaccine against S. aureus in healthy pregnant heifers
Pujato, Nazarena; Camussone, Cecilia; Renna, María Sol; Perrig, Melina Soledad; Morein, Bror; Calvinho, Luis Fernando; Marcipar, Iván Sergio (2018-05)Staphylococcus aureus is a worldwide pathogen that causes mastitis in dairy herds. Shortcomings in control programs have encouraged the development of vaccines against this pathogen. This study evaluated the vaccine candidate ... -
Immune response and functional role of antibodies raised in heifers against a Staphylococcus aureus CP5 lysate and recombinant antigens vaccine formulated with Iscom Matrix adjuvant
Camussone, Cecilia; Pujato, Nazarena; Renna, María Sol; Veaute, Carolina Melania Isabel; Morein, Bror; Marcipar, Iván Sergio; Calvinho, Luis Fernando (2014-12-15)Staphylococcus aureus is the most frequently isolated pathogen from bovine intramammary infections worldwide. Commercially available vaccines for mastitis control are composed either of S. aureus lysates or inactivated ... -
Immune response of heifers against a Staphylococcus aureus CP5 whole cell and lysate vaccine formulated with ISCOM Matrix adjuvant
Camussone, Cecilia; Veaute, Carolina Melania Isabel; Pujato, Nazarena; Morein, Bror; Marcipar, Iván Sergio; Calvinho, Luis Fernando (2014-02)Staphylococcus aureus is the most frequently isolated pathogen from bovine intramammary infections worldwide. Commercially available vaccines for mastitis control are composed either of S. aureus lysates or whole-cells ... -
Preparation and characterization of a Staphylococcus aureus capsular polysaccharide-protein conjugate prepared by a low cost technique: a proof-of-concept study
Pujato, Nazarena; Díaz, Germán; Barbagelata, Maria Sol; Vicco, Miguel Hernán; Calvinho, Luis Fernando; Marcipar, Ivan Sergio (2015-01)Staphylococcus aureus is a worldwide distributed pathogen that produces several diseases in many species and is the major cause of mastitis in dairy cows. S. aureus capsular polysaccharide 5 (CP5) has been widely proposed ... -
Survey of potential factors involved in the low frequency of CP5 and CP8 expression in Staphylococcus aureus isolates from mastitis of dairy cattle from Argentina, Chile, and Uruguay
Ambroggio, Maria Belen; Perrig, Melina Soledad; Camussone, Cecilia; Pujato, Nazarena; Bertón, Alicia; Gianneechini, Edgardo; Alvarez, Silvia; Marcipar, Ivan Sergio; Calvinho, Luis Fernando; Barbagelata, Maria Sol (2018-08)Staphylococcus aureus produces capsular polysaccharides (CPs) both in vivo and under defined culture conditions being serotypes 5 and 8 the most prevalent. S. aureus isolates that fail to produce CP5 or CP8 are defined as ...