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resumen

Resumen
Introduction: Bovine tuberculosis (bTB) constitutes a problem for livestock and Public Health due to its negative impact on farms and its zoonotic nature. In Argentina, the application of the National Control and Eradication Program reduced bTB prevalence. Due to its complexity, the disease continues to be a challenge. Vaccination, as a complementary control tool, could reduce its impact on cattle. Currently, there is no commercial vaccine approved for [ver mas...]
dc.contributor.authorFerrara Muñiz, Ximena
dc.contributor.authorBlanco, Federico Carlos
dc.contributor.authorGarcia, Elizabeth Andrea
dc.contributor.authorDelgado, Fernando Oscar
dc.contributor.authorMarfil, Maria Jimena
dc.contributor.authorZumarraga, Martin Jose
dc.contributor.authorCataldi, Angel Adrian
dc.contributor.authorEirin, Maria Emilia
dc.date.accessioned2024-07-12T11:03:04Z
dc.date.available2024-07-12T11:03:04Z
dc.date.issued2024-06
dc.identifier.urihttp://hdl.handle.net/20.500.12123/18472
dc.descriptionPoster
dc.description.abstractIntroduction: Bovine tuberculosis (bTB) constitutes a problem for livestock and Public Health due to its negative impact on farms and its zoonotic nature. In Argentina, the application of the National Control and Eradication Program reduced bTB prevalence. Due to its complexity, the disease continues to be a challenge. Vaccination, as a complementary control tool, could reduce its impact on cattle. Currently, there is no commercial vaccine approved for its use in bovines. Two attenuated strains, M. bovis Δmce2 and M. bovis Δmce2-phoP1,2 induced protection against a virulent Mycobacterium bovis (M. bovis) strain, during a challenge in cattle3 and the murine model4, respectively. The objective of this work was to evaluate the virulence and safety of M. bovis Δmce2 and M. bovis Δmce2-phoP in mice and guinea pigs, to compare how these two strains behave in both animal models.eng
dc.formatapplication/pdfes_AR
dc.language.isoenges_AR
dc.publisherEuropean Society of Mycobacteriologyes_AR
dc.rightsinfo:eu-repo/semantics/openAccesses_AR
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/es_AR
dc.source44th Annual Congress of the European Society of Mycobacteriology. Brujas, Bélgica, 23-26 de junio de 2024es_AR
dc.subjectMycobacterium bovises_AR
dc.subjectAnimal Modelseng
dc.subjectModelo Animales_AR
dc.subjectBovine Tuberculosiseng
dc.subjectTuberculosis Bovinaes_AR
dc.subjectVirulenceeng
dc.subjectVirulenciaes_AR
dc.subjectSafetyeng
dc.subjectSeguridades_AR
dc.subjectMiceeng
dc.subjectRatónes_AR
dc.subjectGuinea Pigseng
dc.subjectCobayaes_AR
dc.titleComparative study of two deleted Mycobacterium bovis strains in experimental animal modelses_AR
dc.typeinfo:ar-repo/semantics/documento de conferenciaes_AR
dc.typeinfo:eu-repo/semantics/conferenceObjectes_AR
dc.typeinfo:eu-repo/semantics/publishedVersiones_AR
dc.rights.licenseCreative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)es_AR
dc.description.origenInstituto de Biotecnologíaes_AR
dc.description.filFil: Ferrara Muñiz, Ximena. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; Argentinaes_AR
dc.description.filFil: Ferrara Muñiz, Ximena. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentinaes_AR
dc.description.filFil: Blanco, Federico Carlos. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; Argentinaes_AR
dc.description.filFil: Blanco, Federico Carlos. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentinaes_AR
dc.description.filFil: Garcia, Elizabeth Andrea. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; Argentinaes_AR
dc.description.filFil: Garcia, Elizabeth Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentinaes_AR
dc.description.filFil: Delgado, Fernando Oscar. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología Veterinaria; Argentinaes_AR
dc.description.filFil: Marfil, Maria Jimena. Universidad de Buenos Aires. Facultad de Ciencias Veterinarias. Cátedra de Enfermedades Infecciosas; Argentinaes_AR
dc.description.filFil: Zumarraga, Martin Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; Argentinaes_AR
dc.description.filFil: Zumarraga, Martin Jose. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentinaes_AR
dc.description.filFil: Cataldi, Angel Adrian. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; Argentinaes_AR
dc.description.filFil: Cataldi, Angel Adrian. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentinaes_AR
dc.description.filFil: Eirin, Maria Emilia. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; Argentinaes_AR
dc.description.filFil: Eirin, Maria Emilia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentinaes_AR
dc.subtypeponencia


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