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Bovine alphaherpesvirus 1 (BoAHV-1) infection affects the production and reproductive performance of dairy and beef livestock, resulting in considerable economic losses. In addition to biosecurity measures, vaccination programs are effective strategies for controlling and preventing BoAHV-1 infection and transmission. We evaluated the serological immune response against BoAHV-1 induced by eight different formulations of commercial vaccines: three modified
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dc.contributor.author | Camargo, Luana | |
dc.contributor.author | Franklin, Yasmin Vieira | |
dc.contributor.author | da Silva, Gustavo Feliciano Resende | |
dc.contributor.author | Santos, Janaína Ferreira | |
dc.contributor.author | Parreño, Gladys Viviana | |
dc.contributor.author | Wigdorovitz, Andres | |
dc.contributor.author | Gomes, Viviani | |
dc.date.accessioned | 2024-06-28T10:55:49Z | |
dc.date.available | 2024-06-28T10:55:49Z | |
dc.date.issued | 2024-06 | |
dc.identifier.issn | 2076-393X | |
dc.identifier.other | https://doi.org/10.3390/vaccines12060615 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12123/18294 | |
dc.identifier.uri | https://www.mdpi.com/2076-393X/12/6/615 | |
dc.description.abstract | Bovine alphaherpesvirus 1 (BoAHV-1) infection affects the production and reproductive performance of dairy and beef livestock, resulting in considerable economic losses. In addition to biosecurity measures, vaccination programs are effective strategies for controlling and preventing BoAHV-1 infection and transmission. We evaluated the serological immune response against BoAHV-1 induced by eight different formulations of commercial vaccines: three modified live vaccines and five killed vaccines containing BoAHV type 1 or types 1 and 5. In the first experiment, 50 BoAHV-1-seronegative guinea pigs were assigned to eight groups; each individual in the treatment groups received two doses (one-fifth of the bovine dose). The second experiment was conducted using 29 crossbred Holstein × Gir heifers in four groups of six to nine animals each. The serological immune response against BoAHV-1 was measured using virus neutralization and enzyme-linked immunosorbent assays to measure the total IgG against BoAHV. We evaluated the effects of the vaccine, time, and interaction of the vaccine and time on neutralizing antibodies against BoAHV-1. Killed vaccines produced low levels of antibodies against BoAHV-1, whereas modified live vaccines produced high levels of antibodies capable of providing neutralizing titers in the vaccinated animals, with the thermosensitive modified live vaccine showing the highest levels of antibodies. | eng |
dc.format | application/pdf | es_AR |
dc.language.iso | eng | es_AR |
dc.publisher | MDPI | es_AR |
dc.rights | info:eu-repo/semantics/openAccess | es_AR |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | es_AR |
dc.source | Vaccines 12 (6) : 615 (Junio 2024) | es_AR |
dc.subject | Vaccination | eng |
dc.subject | Vacunación | es_AR |
dc.subject | Dairy Cattle | eng |
dc.subject | Ganado de Leche | es_AR |
dc.subject | Vaccines | eng |
dc.subject | Vacuna | es_AR |
dc.subject | Antibodies | eng |
dc.subject | Anticuerpos | es_AR |
dc.subject | Guinea Pigs | eng |
dc.subject | Cobaya | es_AR |
dc.subject | Heifers | eng |
dc.subject | Novilla | es_AR |
dc.subject.other | Bovine alphaherpesvirus 1 | eng |
dc.title | Serological responses of Guinea pigs and heifers to eight different BoAHV-1 vaccine formulations | es_AR |
dc.type | info:ar-repo/semantics/artículo | es_AR |
dc.type | info:eu-repo/semantics/article | es_AR |
dc.type | info:eu-repo/semantics/publishedVersion | es_AR |
dc.rights.license | Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) | es_AR |
dc.description.origen | Instituto de Virología | es_AR |
dc.description.fil | Fil: Camargo, Luana. Universidade de São Paulo. Department of Medical Clinic; Brasil | es_AR |
dc.description.fil | Fil: Franklin, Yasmin Vieira. Universidade de São Paulo. Department of Medical Clinic; Brasil | es_AR |
dc.description.fil | Fil: da Silva, Gustavo Feliciano Resende. Universidade Federal de Goiânia. Department of Animal Production; Brasil | es_AR |
dc.description.fil | Fil: Santos, Janaína Ferreira. Universidade de São Paulo. Department of Medical Clinic; Brasil | es_AR |
dc.description.fil | Fil: Parreño, Gladys Viviana. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virologia e Innovaciones Tecnologicas (IVIT); Argentina | es_AR |
dc.description.fil | Fil: Wigdorovitz, Andres. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología e Innovaciones Tecnológicas (IVIT); Argentina | es_AR |
dc.description.fil | Fil: Gomes, Viviani. Universidade de São Paulo. Department of Medical Clinic; Brasil | es_AR |
dc.subtype | cientifico |
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