Instituto de Virología: Envíos recientes
Mostrando ítems 81-100 de 226
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Bovine interferon lambda Is a potent antiviral against SARS-CoV-2 infection in vitro
(Frontiers Media, 2020-11)Interferon lambda (IFN-λ) is an antiviral naturally produced in response to viral infections, with activity on cells of epithelial origin and located in the mucosal surfaces. This localized activity results in reduced ... -
Optimized adenoviral vector that enhances the assembly of FMDV O1 virus-like particles in situ increases its potential as vaccine for serotype O viruses
(Frontiers Media, 2020-11)Although replication-defective human adenovirus type 5 (Ad5) vectors that express in situ the capsid-encoding region of foot-and-mouth disease virus (FMDV) have been proven to be effective as vaccines in relevant species ... -
Interferon lambda protects cattle against bovine viral diarrhea virus infection
(Elsevier, 2020-12)Interferon lambda (IFN-λ) plays an important role in inducing an antiviral state in mucosal surfaces and has been used as an effective biotherapeutic against several viral diseases. Here we performed a proof of concept ... -
A new molecular method for the rapid subtyping of bovine herpesvirus 1 field isolates
(Sage Publications, 2020-02)Bovine herpesvirus 1 (BoHV-1) causes several clinical syndromes in cattle worldwide. There are 3 subtypes of BoHV-1: 1.1, 1.2a, and 1.2b. Several molecular methods are commonly used in the detection and characterization ... -
Mecanismos involucrados en la duración de la respuesta inmune humoral al virus de la fiebre aftosa
(Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 1996)La fiebre aftosa constituye un serio problema sanitario que afecta a las especies biunguladas que genera severas consecuencias económicas a nivel mundial. Las vacunas formuladas con virus inactivado como antígeno (Ag) ... -
Dynamics of neutralizing antibodies against Bovine respiratory syncytial virus in a dairy herd from Santa Fe Province, Argentina = Dinámica de anticuerpos neutralizantes contra el virus respiratorio sincitial bovino en un rodeo lechero de la provincia de Santa Fe, Argentina
(Elsevier, 2020-05)Bovine respiratory syncytial virus (BRSV) is one of the most relevant agents responsible for respiratory disease in cattle from both dairy and beef farms. BRSV is spread by horizontal contact causing a constant presence ... -
Mouse model as an efficacy test for foot‐and‐mouth disease vaccines
(Wiley, 2020-04)Protection against foot‐and‐mouth disease virus (FMDV) has been linked to the development of a humoral response. In Argentina, the official control tests for assessing the potency of FMD vaccines are protection against ... -
Topical ganciclovir reduces viral excretion in mares with equine coital exanthema
(Elsevier, 2020-07)Equid alphaherpesvirus 3 (EHV-3) is the etiological agent of equine coital exanthema (ECE). Since no vaccines or antiviral therapies are available, prevention consists of clinical examination of mares and stallions before ... -
Inmunidad adaptativa y protectora contra el virus de la fiebre aftosa en bovinos : rol de las respuestas inmunes sistémica y de mucosas
(Facultad de Ciencias Veterinarias, Universidad de Buenos Aires, 2018)La fiebre aftosa (FA) es una enfermedad viral infectocontagiosa de curso agudo que se caracteriza por producir lesiones vesiculares en tejidos de la mucosa oronasal (incluyendo lengua, encías y paladar), ubres, espacios ... -
The role of viral particle integrity in the serological assessment of foot-and-mouth disease virus vaccine-induced immunity in swine
(Plos One, 2020-05)The efficacy of foot-and-mouth disease virus (FMDV) inactivated vaccines is mainly dependent on the integrity of the whole (146S) viral particles. If the intact capsids disassemble to 12S subunits, antibodies against ... -
Actividad del interferón de tipo III contra el virus de la diarrea viral bovina
(Facultad de Ciencias Veterinarias, Universidad de Buenos Aires, 2019)El Virus de la Diarrea Viral Bovina (VDVB) representa un importante desafío a nivel productivo debido a su carácter endémico a nivel mundial. La infección por el VDVB es altamente prevalente en la Argentina y provoca ... -
Development and validation of a novel ELISA for the detection of Neospora caninum antibodies in bovine sera
(Annex Publishers, 2019-08-26)Neospora caninum is a world-wide distributed apicomplexan parasite, causative agent of bovine neosporosis, which is one of the major causes of reproductive losses in cattle affecting both dairy and beef industries. Several ... -
First characterization of a canine parvovirus causing fatal disease in coatis (Nasua nasua)
(Springer, 2019-12)A canine parvovirus (CPV)-like virus was detected by PCR and isolated from dead coatis in Argentina. Analysis of the full-length genome sequence revealed that it resembled CPV-but also contained a mutation in the VP2 protein ... -
Experimental infection of sheep with bovine leukemia virus (BLV): minimum dose of BLV-FLK cells and cell-free BLV and neutralization activity of natural antibodies = Infección experimental en ovinos con el virus de leucosis bovina: dosis mínima de células BLV-FLK y virus libre de células, y actividad neutralizante de anticuerpos naturales
(Elsevier España, 2019-12)Bovine leukemia virus (BLV) is an important cattle pathogen that causes major economic losses worldwide, especially in dairy farms. The use of animal models provides valuable insight into the pathogenesis of viral infections. ... -
Equine influenza virus in Asia: phylogeographic pattern and molecular features reveal circulation of an autochthonous lineage
(American Society for Microbiology, 2019-07)Equine influenza virus (EIV) causes severe acute respiratory disease in horses. Currently, the strains belonging to the H3N8 subtype are divided into two clades, Florida clade 1 (FC1) and Florida clade 2 (FC2), which emerged ... -
Seroprevalencia de leucosis enzoótica bovina en tambos del sur de la provincia de Córdoba, Argentina = Seroprevalence of enzootic bovine leucosis in dairy farms in the south of the province of Córdoba, Argentina
(2019-03)La Leucosis Enzoótica Bovina (LEB) afecta al tejido linfoide y el rasgo patológico distintivo es la transformación neoplásica de linfocitos B, su frecuencia es predominante en el ganado lechero adulto. Existen pocos estudios ... -
Stress response at different ages of weaning in cattle
(Infogain Publication, 2019-02)Weaning is an inherent husbandry practice in cow-calf beef production systems that impose physical, psychological, and nutritional stressors on calves. In order to characterize the main stressors and corresponding stress ... -
Molecular characterization of pestiviruses in fetal bovine sera originating from Argentina: evidence of circulation of HoBi-like viruses
(Frontiers Media, 2019-10)Serological evidence suggests that HoBi-like viruses, an emerging species within the Pestivirus genus of the Flaviviridae family, are in circulation in Argentina. While HoBi-like viruses were first isolated from Brazilian ... -
A direct high-throughput in Cell-ELISA for measuring infectivity of cytopathic and non-cytopathic bovine viral diarrhoea virus strains applied to the assessment of antiviral activity
(Elsevier, 2018-07-19)Low-cost high-throughput methods applicable to any virus strain are required for screening antiviral compounds against multiple field strains. Colorimetric cell-viability assays are used for this purpose as long as the ... -
Bovine coronavirus in Uruguay: genetic diversity, risk factors and transboundary introductions from neighboring countries
(Springer, 2019-11)Bovine coronavirus (BCoV) is a recognized cause of severe neonatal calf diarrhea, with a negative impact on animal welfare, leading to economic losses to the livestock industry. Cattle production is one of the most important ...