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Optimized adenoviral vector that enhances the assembly of FMDV O1 virus-like particles in situ increases its potential as vaccine for serotype O viruses

Ziraldo, Micaela; Bidart, Juan Esteban; Prato, Cecilia A.; Tribulatti, María Virginia; Zamorano, Patricia Ines; Mattion, Nora Marta; D’Antuono, Alejandra (Frontiers Media, 2020-11)

Although replication-defective human adenovirus type 5 (Ad5) vectors that express in situ the capsid-encoding region of foot-and-mouth disease virus (FMDV) have been proven to be effective as vaccines in relevant species ...