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A novel type 1 cystatin involved in the regulation of Rhipicephalus microplus midgut cysteine proteases
(Elsevier, 2020-05)Rhipicephalus microplus is a cattle ectoparasite found in tropical and subtropical regions around the world with great impact on livestock production. R. microplus can also harbor pathogens, such as Babesia sp. and Anaplasma ... -
Characterization of a papain-like cysteine protease essential for the survival of Babesia ovis merozoites
(2016)Babesia ovis, a tick-transmitted intraerythrocytic protozoan parasite, causes severe infections in small ruminants from Southern Europe, Middle East, and Northern Africa. With the aim of finding potential targets for the ... -
Cysteine proteinase C1A paralog profiles correspond with phylogenetic lineages of pathogenic piroplasmids
(MDPI, 2018-04)Piroplasmid parasites comprising of Babesia, Theileria, and Cytauxzoon are transmitted by ticks to farm and pet animals and have a significant impact on livestock industries and animal health in tropical and subtropical ... -
Kinetic characterization of a novel cysteine peptidase from the protozoan Babesia bovis, a potential target for drug design
(Elsevier, 2020-12)C1A cysteine peptidases have been shown to play an important role during apicomplexan invasion and egress of host red blood cells (RBCs) and therefore have been exploited as targets for drug development, in which peptidase ...