Temas 

Temas

Mostrando ítems 1-3 de 3

    • Artificial microRNAs as antiviral strategy to FMDV: structural implications of target selection 

      Gismondi, Maria Ines; Ortiz, Xoana P.; Curra, Anabella Paola; Asurmendi, Sebastian; Taboga, Oscar Alberto (2014-04)
      RNA interference (RNAi) appears as a promising strategy to control virus replication. While the antiviral power of short-hairpin RNAs or small-interfering RNAs against FMDV has been demonstrated widely, safer RNAi effectors ...

    • Genome-wide identification of MITE-derived microRNAs and their targets in bread wheat 

      Crescente, Juan Manuel; Zavallo, Diego; Del Vas, Mariana; Asurmendi, Sebastian; Helguera, Marcelo; Fernandez, Elmer; Vanzetti, Leonardo Sebastian (BioMed Central, 2022-02)
      Background: Plant miRNAs are a class of small non-coding RNAs that can repress gene expression at the post-transcriptional level by targeting RNA degradation or promoting translational repression. There is increasing ...

    • TuMV infection alters the regulation of miR168/AGO1 and miR403/AGO2 systems in Arabidopsis 

      Manacorda, Carlos Augusto; Tasselli, Sabrina; Marano, María Rosa; Asurmendi, Sebastian (Springer, 2024)
      Plant argonaute (AGO) proteins—chiefly AGO1 and 2—restrict viral infections. AGO1/2 also participate in developmental processes and are tightly regulated by microRNAs. Researchers have conducted extensive studies on the ...