Temas 

Temas

Mostrando ítems 1-10 de 10

    • A transcriptional analysis of cattle immune cells reveals a central role of type 1 interferon in the In vitro innate immune response against Mycobacterium bovis 

      Blanco, Federico Carlos; Bigi, María Mercedes; Garcia, Elizabeth Andrea; Elola, María Teresa; Vazquez, Cristina Lourdes; Bigi, Fabiana (MDPI, 2023-09)
      Bovine tuberculosis is a chronic infectious disease primarily caused by Mycobacterium bovis, a bacterium that affects cattle and other mammals, including humans. Despite the availability of vast research about the immune ...

    • Assessing the impact of various tuberculin PPD brands on bovine tuberculosis diagnosis 

      Echeverria, Gustavo; Zumarraga, Martin Jose; Proaño‑Pérez, Freddy; Barceló Blasco, Francisco; Waard, Jacobus H. de (Springer Nature, 2024-03)
      Although several brands of tuberculin purified protein derivatives (PPDs) are available for diagnosing bovine tuberculosis (bTB), comparative studies to determine their diagnostic accuracy are infrequent. In Ecuador we ...

    • Assessment of tuberculosis biomarkers in paratuberculosis-infected cattle 

      Klepp, Laura Ines; Colombatti Olivieri, Maria Alejandra; Moyano, Roberto Damian; Romano, Maria Isabel; Malovrh, Tadej; Ocepek, Matjaž; Blanco, Federico Carlos; Bigi, Fabiana (Sciendo, 2023-03)
      Introduction: Mycobacterium bovis and Mycobacterium avium subsp. paratuberculosis, respectively the causative agents of bovine tuberculosis (bTB) and bovine paratuberculosis (PTB), share a high number of antigenic proteins. ...

    • Comparative study of two deleted Mycobacterium bovis strains in experimental animal models 

      Ferrara Muñiz, Ximena; Blanco, Federico Carlos; Garcia, Elizabeth Andrea; Delgado, Fernando Oscar; Marfil, Maria Jimena; Zumarraga, Martin Jose; Cataldi, Angel Adrian; Eirin, Maria Emilia (European Society of Mycobacteriology, 2024-06)
      Introduction: Bovine tuberculosis (bTB) constitutes a problem for livestock and Public Health due to its negative impact on farms and its zoonotic nature. In Argentina, the application of the National Control and Eradication ...

    • Comparison of DRB3.2 alleles among false-negative and positive tuberculin skin test cattle with bovine tuberculosis 

      Encinas, Micaela; Ferrara Muñiz, Ximena; Sammarruco, Romina Ayelén; Ruiz Menna, Victoria Aymara; Garro, Carlos Javier; Delgado, Fernando Oscar; Zumarraga, Martin Jose; Garbaccio, Sergio Gabriel; Carignano, Hugo Adrian; Eirin, Maria Emilia (European Society of Mycobacteriology, 2024-06)
      Introduction: M. bovis is worldwide distributed mainly affecting livestock. Caudal Fold-Tuberculin Skin Test (CF-TST) is the primary screening tool that detects the infection in herds. Some tuberculous animals remain ...

    • Limited usefulness of the IS6110 touchdown-PCR in blood for tuberculin skin test false-negative cattle with serological response to Mycobacterium bovis 

      Encinas, Micaela; Ferrara Muñiz, Ximena; Sammarruco, Romina Ayelén; Ruiz Menna, Victoria Aymara; Garro, Carlos Javier; Delgado, Fernando Oscar; Macías, Analía; Magnano, Gabriel; Zumarraga, Martin Jose; Garbaccio, Sergio Gabriel; Eirin, Maria Emilia (Frontiers Media, 2024-05)
      Ante-mortem diagnosis of bovine tuberculosis (bTB) is based mainly on the tuberculin skin test (TST) and the ɣ-IFN release assay (IGRA). Some infected animals escape screening tests, thus, limit herd sanitation. Previous ...

    • Live attenuated Mycobacterium bovis strains combined with the encapsulated H65 antigen as a vaccine strategy against bovine tuberculosis in a mouse model 

      Onnainty, Renée; Marini, M. Rocío; Gravisaco, María José; Garcia, Elizabeth Andrea; Aagaard, Claus; Canal, Ana María; Granero, Gladys; Bigi, Fabiana; Blanco, Federico Carlos (Elsevier, 2024-04)
      Mycobacterium bovis is an etiological agent of bovine tuberculosis (bTB) that also infects other mammals, including humans. The lack of an effective vaccine for the control of bTB highlights the need for developing new ...

    • Mycobacterium bovis ESAT-6, CFP-10 and EspC antigens show high conservation among field isolates 

      Encinas, Micaela; Marfil, Maria Jimena; Garbaccio, Sergio Gabriel; Barandiaran, Soledad; Huertas, Pablo Sebastian; Morsella, Claudia Graciela; Macias, Analía; Magnano, Gabriel; Zapata, L.; Bigi, Fabiana; Cataldi, Angel Adrian; Paolicchi, Fernando; Zumarraga, Martin Jose; Eirin, Maria Emilia (Elsevier, 2018-07)
      ESAT-6, CFP-10 and EspC are virulence factors that have been extensively assayed for bovine and human tuberculosis diagnosis due their potent T-cell inducing activities. While polymorphisms of ESAT-6 and CFP-10 were analyzed, ...

    • The subunit vaccine H65 + CAF01 increased the BCG- protection against Mycobacterium bovis infection in a mouse model of bovine tuberculosis 

      Blanco, Federico Carlos; Garcia, Elizabeth Andrea; Aagaard, Claus; Bigi, Fabiana (Elsevier, 2021-05)
      H65, a fusion protein of three pairs of ESX-secreted antigens of Mycobacterium tuberculosis and Mycobacterium bovis, formulated with the liposomal adjuvant CAF01 has been shown to confer protection against M. tuberculosis ...

    • Tuberculosis in wild pigs from Argentina 

      Barandiaran, Soledad; Marfil, Maria Jimena; La Sala, Luciano Francisco; Tammone, Agostina; Condori, Walter Ezequiel; Winter, Marina; Abate, Sergio; Rosas, Ana Carolina; Ponce, Loredana; Carpinetti, Bruno Nicolás; Serena, Maria Soledad; Lozano Calderon, Laura Camila; Zumarraga, Martin Jose (Springer, 2024)
      Mycobacterium bovis, a member of the Mycobacterium tuberculosis complex (MTC) and non-tuberculous Mycobacteria (NTM), may infect wild and domestic mammals, including humans. Although cattle are the main hosts and spreaders ...