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Artificial microRNAs as antiviral strategy to FMDV: structural implications of target selection
(2014-04)RNA interference (RNAi) appears as a promising strategy to control virus replication. While the antiviral power of short-hairpin RNAs or small-interfering RNAs against FMDV has been demonstrated widely, safer RNAi effectors ... -
Assessing small RNA profles in potato diploid hybrid and its resynthesized allopolyploid reveals conserved abundance with distinct genomic distribution
(Springer, 2024-04)Allopolyploidy, a complex process involving interspecific hybridization and whole genome duplication, significantly impacts plant evolution, leading to the emergence of novel phenotypes. Polyploids often present phenotypic ... -
Bases moleculares de la interacción virus-planta : relación entre genes de defensa, ARNs pequeños y sintomatología
(Facultad de Agronomía, Universidad de Buenos Aires, 2013-03)Los virus fitopatógenos producen alteraciones en el metabolismo y la fisiología de sus huéspedes provocadas principalmente por alteraciones en la expresión génica durante las infecciones. Numerosos cambios están asociados ... -
Cestode parasites release extracellular vesicles with microRNAs and immunodiagnostic protein cargo
(2017-09)Intercellular communication is crucial in multiple aspects of cell biology. This interaction can be mediated by several mechanisms including extracellular vesicle (EV) transfer. EV secretion by parasites has been reported ... -
Changes in micro RNA expression in a wild tuber-bearing Solanum species induced by 5-Azacytidine treatment
(2012-08)Phenotypic plasticity is often postulated as a principal characteristic of tuber-bearing wild Solanum species. The hypotheses to explore this observation have been developed based on the presence of genetic variation. In ... -
Citrus psorosis virus 24K protein interacts with citrus miRNA precursors, affects their processing and subsequent miRNA accumulation and target expression
(2016-04)Sweet orange (Citrus sinensis), one of the most important fruit crops worldwide, may suffer from disease symptoms induced by virus infections, thus resulting in dramatic economic losses. Here, we show that the infection ... -
Differential mRNA accumulation upon early arabidopsis thaliana infection with ORMV and TMV-Cg Is associated with distinct endogenous small RNAs Level
(2015-08-03)Small RNAs (sRNAs) play important roles in plant development and host-pathogen interactions. Several studies have highlighted the relationship between viral infections, endogenous sRNA accumulation and transcriptional ... -
Genome-wide identification of microRNA targets in the neglected disease pathogens of the genus Echinococcus
(2017-06)MicroRNAs (miRNAs), a class of small non-coding RNAs, are key regulators of gene expression at posttranscriptional level and play essential roles in biological processes such as development. MiRNAs silence target mRNAs by ... -
Mal de Río Cuarto Virus infection triggers the production of distinctive viral-derived siRNA profiles in wheat and Its planthopper vector
(2017)Plant reoviruses are able to multiply in gramineae plants and delphacid vectors encountering different defense strategies with unique features. This study aims to comparatively assess alterations of small RNA (sRNA) ... -
MicroRNA analysis of Taenia crassiceps cysticerci under praziquantel treatment and genome-wide identification of Taenia solium miRNAs
(2017-09)MicroRNAs (miRNAs) are small non-coding RNAs that have emerged as important regulators of gene expression and perform critical functions in development and disease. In spite of the increased interest in miRNAs from helminth ... -
The P0 protein encoded by cotton leafroll dwarf virus (CLRDV) inhibits local but not systemic RNA silencing
(2014-02)Plants employ RNA silencing as a natural defense mechanism against viruses. As a counter-defense, viruses encode silencing suppressor proteins (SSPs) that suppress RNA silencing. Most, but not all, the P0 proteins encoded ... -
TMV induces RNA decay pathways to modulate gene silencing and disease symptoms
(2017)RNA decay pathways comprise a combination of RNA degradation mechanisms that are implicated in gene expression, development and defense responses in eukaryotes. These mechanisms are known as the RNA Quality Control or RQC ... -
Transgenic expression of tobacco mosaic virus capsid and movement proteins modulate plant basal defense and biotic stress responses in Nicotiana tabacum
(2012)Plant viruses cause metabolic and physiological changes associated with symptomatic disease phenotypes. Symptoms involve direct and indirect effects, which result in disruption of host physiology. We used transgenic ...