• Successful production of the potato antimicrobial peptide Snakin-1 in baculovirus-infected insect cells and development of specific antibodies 

      Almasia, Natalia Ines; Molinari, Maria Paula; Maroniche, Guillermo Andrés; Nahirñak, Vanesa; Barrios Baron, Maria Pilar; Taboga, Oscar Alberto; Vazquez Rovere, Cecilia (2017)
      Background: Snakin-1 (StSN1) is a broad-spectrum antimicrobial cysteine-rich peptide isolated from Solanum tuberosum. Its biotechnological potential has been already recognized since it exhibits in vivo antifungal and ...
    • Sunflower germin-like protein HaGLP1 promotes ROS accumulation and enhances protection against fungal pathogens in transgenic Arabidopsis thaliana 

      Beracochea, Valeria Cecilia; Almasia, Natalia Ines; Peluffo, Lucila; Nahirñak, Vanesa; Hopp, Horacio Esteban; Paniego, Norma Beatriz; Heinz, Ruth Amelia; Vazquez Rovere, Cecilia; Lia, Veronica Viviana (Springer, 2015-10)
      Germin-like proteins (GLPs) are a large, diverse and ubiquitous family of plant glycoproteins belonging to the Cupin super family. These proteins have been widely studied because of their diverse roles in important plant ...
    • Sunflower leaf senescence : a complex genetic process with economic impact on crop production 

      Moschen, Sebastian Nicolas; López Gialdi, Agustín I.; Paniego, Norma Beatriz; Fernandez, Paula del Carmen; Heinz, Ruth Amelia (2017)
      Leaf senescence is a complex process controlled by multiple genetic and environmental variables. In different crops, a delay in leaf senescence has an important impact on grain yield trough the maintenance of the photosynthetic ...
    • Sunflower: a potential fructan-bearing crop? 

      Martínez-Noël, Giselle M. A.; Dosio, Guillermo; Puebla, Andrea Fabiana; Insani, Ester Marina; Tognetti, Jorge (2015-10)
      Grain filling in sunflower (Helianthus annuus L.) mainly depends on actual photosynthesis, being the contribution of stored reserves in stems (sucrose, hexoses, and starch) rather low. Drought periods during grain filling ...
    • Surface Display of AcMNPV Occlusion-Derived P74 Does Not Enhance Oral Infectivity of Budded Viruses 

      Alfonso, Victoria; Lopez, Maria Gabriela; Carrillo, Elisa Cristina; Taboga, Oscar Alberto (S. Karger AG, 2012-02)
      Baculovirus occlusion-derived viruses (ODVs) and budded viruses (BVs) are morphologically and functionally distinct. ODVs are responsible for primary infection in insect hosts because of their high per os infectivity. On ...
    • Surveillance and characterization of drug‑resistant mycobacterium tuberculosis isolated in a reference hospital from Argentina during 8 years’ period 

      Imperiale, Belen Rocio; Di Giulio, Angela Beatríz; Mancino, María Belén; Zumarraga, Martin Jose; Morcillo, Nora (Wolters Kluwer, 2019-09)
      Background: Argentina is considered a country with a middle tuberculosis (TB) incidence. However, according to the last national epidemiological report released in 2018, since 2013, the trends are steadily increasing. The ...
    • Symbionts do not affect the mating incompatibility between the Brazilian-1 and Peruvian morphotypes of the Anastrepha fraterculus cryptic species complex 

      Devescovi, Francisco; Conte, Claudia Alejandra; Augustinos, Antonios A.; Cancio Martinez, Elena I.; Segura, Diego Fernando; Caceres, Carlos; Lanzavecchia, Silvia Beatriz; Bourtzis, Kostas (Springer Nature, 2019-12)
      The South American fruit fly, Anastrepha fraterculus, is clearly undergoing a speciation process. Among others, two of their morphotypes, the Brazilian-1 and Peruvian, have accumulated differences in pre- and post-zygotic ...
    • Synergic activity of Cel8Pa β-1,4 endoglucanase and Bg1Pa β-glucosidase from Paenibacillus xylanivorans A59 in beta-glucan conversio 

      Ghio, Silvina; Bradanini, María B.; Garrido, Mercedes Maria; Ontañon, Ornella Mailen; Piccinni, Florencia Elizabeth; Marrero Diaz De Vill, Rubén; Talia, Paola Mónica; Campos, Eleonora (Elsevier, 2020-12)
      In the efficient bioconversion of polysaccharides from lignocellulosic biomass, endoglucanases and β-glucosidases are key enzymes for the deconstruction of β-glucans. In this work, we focused on a GH8 endoglucanase ...
    • Systemic administration of imiquimod as an adjuvant improves immunogenicity of a tumor-lysate vaccine inducing the rejection of a highly aggressive T-cell lymphoma 

      Di Sciullo, Maria Paula; Menay, Florencia; Cocozza, Federico; Gravisaco, María José; Waldner, Claudia Inés; Mongini, Claudia (Elsevier, 2019-06)
      T-cell lymphomas include diverse malignancies. They are rare, some have low survival rates and they lack curative therapies. The aim of this work was to assess whether employing the TLR7 agonist imiquimod and the T-cell ...
    • The ALS gene as genetic target in CRISPR/ cas approaches: what have we learned so far? 

      Darqui, Flavia Soledad; Hopp, Horacio Esteban; Lopez Bilbao, Marisa Gisela (Crimson Publishers, 2020-08)
      Specific mutations in the conserved domains of the acetolactate synthase (ALS) gene conduct to different key amino acid substitutions that can confer herbicide resistance in different plant species. This outcome has been ...
    • The autographa californica multiple nucleopolyhedrovirus Ac12: A non-essential F box-like protein that interacts with cellular SKP1 component of the E3 ubiquitin ligase complex 

      Costa Navarro, Guadalupe Soledad; Amalfi, Sabrina; Lopez, Maria Gabriela; Llauger, Gabriela; Arneodo Larochette, Joel Demian; Taboga, Oscar Alberto; Alfonso, Victoria (Elsevier, 2019-01)
      The Autographa californica multiple nucleopolyhedrovirus (AcMNPV) ac12 gene, which is conserved in ten other baculovirus, codes a predicted 217 amino acid protein of unknown function. In this study, we investigated the ...
    • The conserved brassinosteroid-related transcription factor BIM1a negatively regulates fruit growth in tomato 

      Mori, Kentaro; Lemaire-Chamley, Martine; Jorly, Joana; Carrari, Fernando; Conte, Mariana; Asamizu, Erika; Mizoguchi, Tsuyoshi; Ezura, Hiroshi; Rothan, Christophe (Oxford University Press, 2021-02)
      Brassinosteroids (BRs) are steroid hormones that play key roles in plant development and defense. Our goal is to harness the extensive knowledge of the Arabidopsis BR signaling network to improve productivity in crop ...
    • The cytosolic invertase NI6 affects vegetative growth, flowering, fruit set, and yield in tomato 

      Coluccio Leskow, Carla; Conte, Mariana; del Pozo, Talía; Bermudez Salazar, Luisa; Lira, Bruno Silvestre; Gramegna, Giovanna; Baroli, Irene; Burgos, Estanislao; Zavallo, Diego; Kamenetzky, Laura; Asis, Ramón; Gonzalez, Maurıcio; Fernie, Alisdair R.; Rossi, Magdalena; Osorio, Sonia; Carrari, Fernando (Oxford University Press, 2021-03)
      Sucrose metabolism is important for most plants, both as the main source of carbon and via signaling mechanisms that have been proposed for this molecule. A cleaving enzyme, invertase (INV) channels sucrose into sink ...
    • The genetic architecture of photosynthesis and plant growthrelated traits in tomato 

      Oliveira Silva, Franklin Magnum de; Lichtenstein, Gabriel; Alseekh, Saleh; Rosado‐Souza, Laise; Conte, Mariana; Fuentes Suguiyama, Vanessa; Lira, Bruno Silvestre; Fanourakis, Dimitrios; Usadel, Björn; Lopes Bhering, Leonardo; DaMatta, Fábio M.; Sulpice, Ronan; Araújo, Wagner L.; Rossi, Magdalena; de Setta, Nathalia; Fernie, Alisdair R.; Carrari, Fernando; Nunes Nesi, Adriano (Wiley, 2018-02)
      To identify genomic regions involved in the regulation of fundamental physiological processes such as photosynthesis and respiration, a population of Solanum pennellii introgression lines was analyzed. We determined ...
    • The genome of the stress-tolerant wild tomato species Solanum pennellii 

      Bolger, Anthony; Scossa, Federico; Bolger, Marie E.; Lanz, Christa; Maumus, Florian; Tohge, Takayuki; Quesneville, Hadi; Alseekh, Saleh; Sørensen, Iben; Lichtenstein, Gabriel; Fich, Eric A.; Conte, Mariana; Keller, Heike; Schneeberger, Korbinian; Schwacke, Rainer; Ofner, Itai; Vrebalov, Julia; Xu, Yimin; Osorio, Sonia; Aflitos, Saulo Alves; Schijlen, Elio; Jiménez-Goméz, José M.; Ryngajllo, Malgorzata; Kimura, Seisuke; Kumar, Ravi; Koenig, Daniel; Headland, Lauren R.; Maloof, Julin N.; Sinha, Neelima; van Ham, Roeland C. H. J.; Lankhorst, René Klein; Mao, Linyong; Vogel, Alexander; Arsova, Borjana; Panstruga, Ralph; Fei, Zhangjun; Rose, Jocelyn K. C.; Zamir, Dani; Carrari, Fernando; Giovannoni, James J.; Weigel, Detlef; Usadel, Björn; Fernie, Alisdair R. (Nature Publishing Group, 2014-09)
      Solanum pennellii is a wild tomato species endemic to Andean regions in South America, where it has evolved to thrive in arid habitats. Because of its extreme stress tolerance and unusual morphology, it is an important ...
    • The Gln15Arg mutation in the transcriptional factor PALM1 produces multifoliate alfalfa 

      Gomez, Maria Cristina; Jozefkowicz, Cintia; Mozzicafreddo, Matteo; Odorizzi, Ariel; Arolfo, Valeria; Basigalup, Daniel Horacio; Ayub, Nicolás Daniel; Soto, Gabriela Cynthia (Springer, 2022-12)
      The CRISPR/Cas9 system has proven to be highly valuable for genome editing in several important crops, including the allogamous tetraploid cultivated alfalfa (Medicago sativa). However, the fact that most of the beneficial ...
    • The heart microbiome of insectivorous bats from Central and South Eastern Europe 

      Corduneanu, Alexandra; Mihalca, Andrei Daniel; Sandor, Attila D.; Hornok, Sándor; Malmberg, Maja; Pin Viso, Natalia Daniela; Bongcam-Rudloff, Erik (Elsevier, 2021-04)
      Host associated microbiome not only may affect the individual health-status or provide insights into the species- or group specific bacterial communities but may act as early warning signs in the assessment of zoonotic ...
    • The key to egress? Babesia bovis perforin-like protein 1 (PLP1) with hemolytic capacity is required for blood stage replication and is involved in the exit of the parasite from the host cell 

      Paoletta, Martina; Laughery, Jacob Michael; Lopez Arias, Ludmila Sol; Jaramillo Ortiz, Jose; Montenegro, Valeria Noely; Petrigh, Romina; Ueti, Massaro W.; Suarez, Carlos Esteban; Farber, Marisa Diana; Wilkowsky, Silvina Elizabeth (Elsevier, 2021-07)
      Bovine babesiosis is a tick-borne disease caused by apicomplexan parasites of the Babesia genus that represents a major constraint to livestock production worldwide. Currently available vaccines are based on live parasites ...
    • The P0 protein encoded by cotton leafroll dwarf virus (CLRDV) inhibits local but not systemic RNA silencing 

      Delfosse, Veronica Cecilia; Agrofoglio, Yamila Carla; Casse, Maria Florencia; Bonacic Kresic, Iván; Hopp, Horacio Esteban; Ziegler-Graff, Véronique; Distefano, Ana Julia (2014-02)
      Plants employ RNA silencing as a natural defense mechanism against viruses. As a counter-defense, viruses encode silencing suppressor proteins (SSPs) that suppress RNA silencing. Most, but not all, the P0 proteins encoded ...
    • The role of glucose in the pathology of EHEC O157: H7 

      Marques Da Silva, Wanderson; Taibo, Catalina Beatriz; Sabio Y Garcia, Julia Veronica; Larzabal, Mariano; Cataldi, Angel Adrian (Cambridge University Press, 2020-04)
      The pathogen enterohemorrhagic Escherichia coli (EHEC) O157: H7 is responsible for hemorrhagic colitis and hemolytic uremic syndrome in humans [1]. During the colonization process in the gastrointestinal tract, EHEC needs ...