autores 

Autores

Mostrando ítems 1-9 de 9

    • A beginner’s guide for FMDV quasispecies analysis: sub-consensus variant detection and haplotype reconstruction using next-generation sequencing 

      Cacciabue, Marco Polo; Curra, Anabella Paola; Carrillo, Elisa Cristina; Konig, Guido Alberto; Gismondi, Maria Ines (Oxford Academic Press, 2020-09)
      Deep sequencing of viral genomes is a powerful tool to study RNA virus complexity. However, the analysis of next-generation sequencing data might be challenging for researchers who have never approached the study of viral ...

    • Antiviral efficacy of short-hairpin RNAs and artificial microRNAs targeting foot and-mouth disease virus 

      Curra, Anabella Paola; Cacciabue, Marco Polo Domingo; Gravisaco, María José; Asurmendi, Sebastian; Taboga, Oscar Alberto; Gismondi, Maria Ines (Peer J Inc., 2021-06)
      RNA interference (RNAi) is a well-conserved mechanism in eukaryotic cells that directs post-transcriptional gene silencing through small RNA molecules. RNAi has been proposed as an alternative approach for rapid and specific ...

    • Artificial microRNAs as antiviral strategy to FMDV: structural implications of target selection 

      Gismondi, Maria Ines; Ortiz, Xoana P.; Curra, Anabella Paola; Asurmendi, Sebastian; Taboga, Oscar Alberto (2014-04)
      RNA interference (RNAi) appears as a promising strategy to control virus replication. While the antiviral power of short-hairpin RNAs or small-interfering RNAs against FMDV has been demonstrated widely, safer RNAi effectors ...

    • Assessing the hidden diversity underlying consensus sequences of SARS-CoV-2 using VICOS, a novel bioinformatic pipeline for identification of mixed viral populations 

      Goya, Stephanie; Sosa, Ezequiel Jorge; Nabaes Jodar, Mercedes Soledad; Torres, Carolina; Konig, Guido Alberto; Acuña, Dolores; Ceballos, Santiago; Distefano, Ana Julia; Dopazo, Hernán; Dus Santos, Maria Jose; Fass, Monica Irinia; Fernandez Do Porto, Darío Augusto; Fernandez, Ailen; Gallego, Fernando; Gismondi, Maria Ines; Gramundi, Ivan; Lusso, Silvina; Marti, Marcelo Adrián; Mazzeo, Melina; Mistchenko, Alicia Susana; Muñoz Hidalgo, Marianne Graziel; Natale, Mónica; Nardi, Cristina; Ousset, Julia; Peralta, Andrea Veronica; Pintos, Carolina; Puebla, Andrea Fabiana; Pianciola, Luis; Rivarola, Maximo Lisandro; Turjanski, Adrián; Valinotto, Laura; Vera, Pablo Alfredo; Zaiat, Jonathan; Zubrycki, Jeremias Enrique; Aulicino, Paula; Viegas, Mariana (Elsevier, 2023-02)
      Introduction: Coinfection with two SARS-CoV-2 viruses is still a very understudied phenomenon. Although next generation sequencing methods are very sensitive to detect heterogeneous viral populations in a sample, there is ...

    • Baculovirus AcMNPV induces type I interferons and NK/NKT cells-mediated protection against foot-and-mouth disease virus in mice 

      Molina, Guido Nicolas; Cacciabue, Marco Polo; Gismondi, Maria Ines; Taboga, Oscar Alberto; Molinari, Maria Paula (Elsevier, 2020-08)
      Foot-and-mouth disease is a viral illness that affects cloven-hoofed animals causing serious economic losses. Inactivated vaccines against its causative agent, foot-and-mouth disease virus (FMDV), require approximately ...

    • Differential replication of Foot-and-mouth disease viruses in mice determine lethality 

      Cacciabue, Marco Polo; Garcia Nuñez, Maria Soledad; Delgado, Fernando Oscar; Curra, Anabella Paola; Marrero Diaz De Villegas, Rubén; Molinari, Maria Paula; Rieder, Elizabeth; Carrillo, Elisa Cristina; Gismondi, Maria Ines (2017-09)
      Adult C57BL/6J mice have been used to study Foot-and-mouth disease virus (FMDV) biology. In this work, two variants of an FMDV A/Arg/01 strain exhibiting differential pathogenicity in adult mice were identified and ...

    • Efficient edition of the bovine PRNP prion gene in somatic cells and IVF embryos using the CRISPR/Cas9 system 

      Bevacqua, Romina Jimena; Fernandez-Martín, R.; Savy, Virginia; Canel, Natalia Gabriela; Gismondi, Maria Ines; Kues, Wilfried A.; Carlson, Daniel F.; Fahrenkrug, S.C.; Niemann, H.; Taboga, Oscar Alberto; Ferraris, Sergio; Salamone, Daniel Felipe (2016-11)
      The recently developed engineered nucleases, such as zinc-finger nucleases, transcription activator-like effector nucleases, and clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated nuclease ...

    • Genome-wide identification of microRNA targets in the neglected disease pathogens of the genus Echinococcus 

      Macchiaroli, Natalia; Maldonado, Lucas; Zarowiecki, Magdalena; Cucher, Marcela Alejandra; Gismondi, Maria Ines; Kamenetzky, Laura; Rosenzvit, Mara Cecilia (2017-06)
      MicroRNAs (miRNAs), a class of small non-coding RNAs, are key regulators of gene expression at posttranscriptional level and play essential roles in biological processes such as development. MiRNAs silence target mRNAs by ...

    • ViralPlaque: a Fiji macro for automated assessment of viral plaque statistics 

      Cacciabue, Marco Polo; Curra, Anabella Paola; Gismondi, Maria Ines (PeerJ, 2019-09)
      laque assay has been used for a long time to determine infectious titers and characterize prokaryotic and eukaryotic viruses forming plaques. Indeed, plaque morphology and dimensions can provide information regarding the ...