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Artificial microRNAs as antiviral strategy to FMDV: structural implications of target selection
(2014-04)RNA interference (RNAi) appears as a promising strategy to control virus replication. While the antiviral power of short-hairpin RNAs or small-interfering RNAs against FMDV has been demonstrated widely, safer RNAi effectors ... -
Bases moleculares de la interacción virus-planta : relación entre genes de defensa, ARNs pequeños y sintomatología
(Facultad de Agronomía, Universidad de Buenos Aires, 2013-03)Los virus fitopatógenos producen alteraciones en el metabolismo y la fisiología de sus huéspedes provocadas principalmente por alteraciones en la expresión génica durante las infecciones. Numerosos cambios están asociados ... -
Bovine leukemia virus small noncoding RNAs are functional elements that regulate replication and contribute to oncogenesis in vivo
(2016-04)Retroviruses are not expected to encode miRNAs because of the potential problem of self-cleavage of their genomic RNAs. This assumption has recently been challenged by experiments showing that bovine leukemia virus (BLV) ... -
Cestode parasites release extracellular vesicles with microRNAs and immunodiagnostic protein cargo
(2017-09)Intercellular communication is crucial in multiple aspects of cell biology. This interaction can be mediated by several mechanisms including extracellular vesicle (EV) transfer. EV secretion by parasites has been reported ... -
Changes in micro RNA expression in a wild tuber-bearing Solanum species induced by 5-Azacytidine treatment
(2012-08)Phenotypic plasticity is often postulated as a principal characteristic of tuber-bearing wild Solanum species. The hypotheses to explore this observation have been developed based on the presence of genetic variation. In ... -
Citrus psorosis virus 24K protein interacts with citrus miRNA precursors, affects their processing and subsequent miRNA accumulation and target expression
(2016-04)Sweet orange (Citrus sinensis), one of the most important fruit crops worldwide, may suffer from disease symptoms induced by virus infections, thus resulting in dramatic economic losses. Here, we show that the infection ... -
Detección de agentes virales presentes en apiarios destinados a la producción de material vivo y evaluación de estrategias para su control mediante ARN interferente
(Facultad de Agronomía, Universidad de Buenos Aires, 2023-11-02)En el sector apícola, Argentina se posiciona como uno de los principales actores a nivel global. La actividad local se destaca principalmente en la producción de miel a granel y otros productos obtenidos de la colmena ... -
Differential mRNA accumulation upon early arabidopsis thaliana infection with ORMV and TMV-Cg Is associated with distinct endogenous small RNAs Level
(2015-08-03)Small RNAs (sRNAs) play important roles in plant development and host-pathogen interactions. Several studies have highlighted the relationship between viral infections, endogenous sRNA accumulation and transcriptional ... -
Genome-wide identification of microRNA targets in the neglected disease pathogens of the genus Echinococcus
(2017-06)MicroRNAs (miRNAs), a class of small non-coding RNAs, are key regulators of gene expression at posttranscriptional level and play essential roles in biological processes such as development. MiRNAs silence target mRNAs by ... -
Mal de Río Cuarto Virus infection triggers the production of distinctive viral-derived siRNA profiles in wheat and Its planthopper vector
(2017)Plant reoviruses are able to multiply in gramineae plants and delphacid vectors encountering different defense strategies with unique features. This study aims to comparatively assess alterations of small RNA (sRNA) ... -
Metabolic and miRNA profiling of TMV infected plants reveals biphasic temporal changes
(2011-12-12)Plant viral infections induce changes including gene expression and metabolic components. Identification of metabolites and microRNAs (miRNAs) differing in abundance along infection may provide a broad view of the pathways ... -
MicroRNA analysis of Taenia crassiceps cysticerci under praziquantel treatment and genome-wide identification of Taenia solium miRNAs
(2017-09)MicroRNAs (miRNAs) are small non-coding RNAs that have emerged as important regulators of gene expression and perform critical functions in development and disease. In spite of the increased interest in miRNAs from helminth ... -
Midgut Genes Knockdown by Oral dsRNA Administration Produces a Lethal Effect on Cotton Boll Weevil
(Springer, 2021-02)The “cotton boll weevil” (Anthonomus grandis Boheman) is a key pest in America whose larval stage develops within the cotton flower bud. During its development, the larva uses the flower bud as food and as a shelter from ... -
mRNA biogenesis-related helicase eIF4AIII from Arabidopsis thaliana is an important factor for abiotic stress adaptation
(2016)Similar to other plant species, Arabidopsis has a huge repertoire of predicted helicases, including the eIF4AIII factor, a putative component of the exon junction complex related to mRNA biogenesis. In this article, we ... -
The P0 protein encoded by cotton leafroll dwarf virus (CLRDV) inhibits local but not systemic RNA silencing
(2014-02)Plants employ RNA silencing as a natural defense mechanism against viruses. As a counter-defense, viruses encode silencing suppressor proteins (SSPs) that suppress RNA silencing. Most, but not all, the P0 proteins encoded ... -
TMV induces RNA decay pathways to modulate gene silencing and disease symptoms
(2017)RNA decay pathways comprise a combination of RNA degradation mechanisms that are implicated in gene expression, development and defense responses in eukaryotes. These mechanisms are known as the RNA Quality Control or RQC ... -
Transcriptomic Survey of the Midgut of Anthonomus grandis (Coleoptera: Curculionidae)
(Entomological Society of America, 2014-11)Anthonomus grandis Boheman is a key pest in cotton crops in the New World. Its larval stage develops within the flower bud using it as food and as protection against its predators. This behavior limits the effectiveness ... -
Transgenic expression of tobacco mosaic virus capsid and movement proteins modulate plant basal defense and biotic stress responses in Nicotiana tabacum
(2012)Plant viruses cause metabolic and physiological changes associated with symptomatic disease phenotypes. Symptoms involve direct and indirect effects, which result in disruption of host physiology. We used transgenic ...