• A single nanobody neutralizes multiple epochally evolving human noroviruses by modulating capsid plasticity 

      Salmen, Wilhelm; Hu, Liya; Bok, Marina; Chaimongkol, Natthawan; Ettayebi, Khalil; Sosnovtsev, Stanislav V.; Soni, Kaundal; Ayyar, B. Vijayalakshmi; Shanker, Sreejesh; Neill, Frederick H.; Sankaran, Banumathi; Atmar, Robert L.; Estes, Mary K.; Green, Kim Y.; Parreño, Gladys Viviana; Prasad, B. V. Venkataram (Nature Publishing Group, 2023-10)
      Acute gastroenteritis caused by human noroviruses (HuNoVs) is a significant global health and economic burden and is without licensed vaccines or antiviral drugs. The GII.4 HuNoV causes most epidemics worldwide. This virus ...
    • Development of recombinant VHH nanobodies as an alternative for clearance of equine arteritis virus in carrier stallions 

      Aduriz Guerrero, Matí­as; Carossino, Mariano; Go, Y.Y.; Vincke, Cécile; Balasuriya, Udeni B.R.; Muyldermans, S.; Wigdorovitz, Andres; Barrandeguy, Maria Edith; Parreño, Viviana (2016)
      In conclusion, a VHH library derived from llama B cells following immunization with EAV was generated. This novel strategy could allow the generation of EAV-specific neutralizing Nbs as a therapeutic approach to induce ...