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Comparison of homologous and heterologous prime-boost immunizations combining MVA-vectored and plant-derived VP2 as a strategy against IBDV

Richetta, Matias Daniel; Gomez, Evangelina Raquel; Lucero, Maria Soledad; Chimeno Zoth, Silvina Andrea; Gravisaco, María José; Calamante, Gabriela; Berinstein, Analia (2017-01)

Different immunogens such as subunit, DNA or live viral-vectored vaccines against Infectious Bursal Disease virus (IBDV) have been evaluated in the last years. However, the heterologous prime-boost approach using recombinant ...
Induction of both local immune response in mice and protection in a rabbit model by intranasal immunization with modified vaccinia ankara virus expressing a secreted form of bovine herpesvirus 1 glycoprotein D

Del Medico Zajac, Maria Paula; Zanetti, Flavia Adriana; Federico, Carlos Rodolfo; Zabal, Osvaldo Alfredo; Valera, Alejandro Rafael; Calamante, Gabriela (2017)

In this study, we evaluated the immunogenicity and efficacy of mucosal delivery of a recombinant modified vaccinia Ankara virus (MVA) expressing the secreted version of bovine herpesvirus type 1 (BoHV-1) glycoprotein D ...