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Characterization of innate immune response to Brucella melitensis infection in goats with permissive or restrictive phenotype for Brucella intramacrophagic growth
(Elsevier, 2021-04)Caprine brucellosis is a chronic, world-wide distributed disease which causes reproductive failure in goats and Brucella melitensis, its causative agent, bears a great zoonotic potential. There is evidence suggesting that ... -
Comparative review of brucellosis in small domestic ruminants
(Frontiers Media, 2022-05)Brucella melitensis and Brucella ovis are the primary etiological agents of brucellosis in small domestic ruminants. B. melitensis was first isolated in 1887 by David Bruce in Malta Island from spleens of four soldiers, ... -
Cytokine expression profile of B. melitensis-infected goat monocyte-derived macrophages
(Elsevier, 2023-05)Brucella parasitize the macrophage where is able to replicate and modulate the immune response in order to establish a chronic infection. The most adequate response to control and eliminate Brucella infection is a type 1 ... -
Estudio de la variabilidad genética de Brucella melitensis en el noroeste de la provincia de San Luis
(Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, 2020)Los objetivos del presente trabajo fueron emplear técnicas de genotipificación molecular en un escenario real, describir genotipos circulantes de Brucella melitensis en el noroeste de la provincia de San Luis y poner a ... -
Evaluation of B. melitensis whole-cell lysate antigen-based indirect ELISA for the serodiagnosis of caprine brucellosis
(Elsevier, 2022-10)Different fractions of Brucella (B) abortus or Brucella melitensis have been used as antigens for the detection of anti-Brucella antibodies in goat sera, being their accomplishment cumbersome and time consuming. In an ... -
Evaluation of the safety profile of the vaccine candidate Brucella melitensis 16MDvjbR strain in goats
(Elsevier, 2021-01)Small ruminant brucellosis is caused by the Gram negative cocci-bacillus Brucella (B.) melitensis, the most virulent Brucella species for humans. In goats and sheep, middle to late-term gestation abortion, stillbirths and ... -
New scenarios for brucella suis and brucella melitensis
(Springer, 2017-03)Purpose of Review: We pretend to highlight the most important advances reached in the last few years in the biology of Brucella suis and Brucella melitensis and focus attention on new tools for the comprehension, prevention ... -
Subcutaneous vaccination of pregnant guinea pigs with Brucella melitensis Rev.1: a model for preliminary study the safety of vaccine candidates against small ruminant brucellosis
(Ediciones INTA, 2024-08)Brucella melitensis is the etiological agent of small ruminant brucellosis and abortion is the only noticeable clinical sign in most cases. Vaccination with the attenuated Rev.1 strain is the best option to prevent this ...