• A beginner’s guide for FMDV quasispecies analysis: sub-consensus variant detection and haplotype reconstruction using next-generation sequencing 

      Cacciabue, Marco Polo; Curra, Anabella Paola; Carrillo, Elisa Cristina; Konig, Guido Alberto; Gismondi, Maria Ines (Oxford Academic Press, 2020-09)
      Deep sequencing of viral genomes is a powerful tool to study RNA virus complexity. However, the analysis of next-generation sequencing data might be challenging for researchers who have never approached the study of viral ...
    • Anthropogenic infection of domestic cats with SARS-CoV-2 alpha variant B.1.1.7 lineage in Buenos Aires 

      Pecora, Andrea; Malacari, Darío Amilcar; Mozgovoj, Marina Valeria; Díaz, María de los Ángeles; Peralta, Andrea Veronica; Cacciabue, Marco Polo Domingo; Puebla, Andrea Fabiana; Carusso, Cristian; Mundo, Silvia Leonor; Gonzalez Lopez Ledesma, María Mora; Gamarnik, Andrea Vanesa; Rinaldi, Osvaldo; Vidal, Osvaldo; Mas, Javier; Dus Santos, Maria Jose (Frontiers Media, 2022-03)
      SARS-CoV-2 reverse zoonosis, particularly to domestic animals, and the potential role of infected animals in perpetuating the spread of the virus is an issue of increasing concern. In this case report, we identified the ...
    • Baculovirus AcMNPV induces type I interferons and NK/NKT cells-mediated protection against foot-and-mouth disease virus in mice 

      Molina, Guido Nicolas; Cacciabue, Marco Polo; Gismondi, Maria Ines; Taboga, Oscar Alberto; Molinari, Maria Paula (Elsevier, 2020-08)
      Foot-and-mouth disease is a viral illness that affects cloven-hoofed animals causing serious economic losses. Inactivated vaccines against its causative agent, foot-and-mouth disease virus (FMDV), require approximately ...
    • Differential replication of Foot-and-mouth disease viruses in mice determine lethality 

      Cacciabue, Marco Polo; Garcia Nuñez, Maria Soledad; Delgado, Fernando Oscar; Curra, Anabella Paola; Marrero Diaz De Villegas, Rubén; Molinari, Maria Paula; Rieder, Elizabeth; Carrillo, Elisa Cristina; Gismondi, Maria Ines (2017-09)
      Adult C57BL/6J mice have been used to study Foot-and-mouth disease virus (FMDV) biology. In this work, two variants of an FMDV A/Arg/01 strain exhibiting differential pathogenicity in adult mice were identified and ...
    • INFINITy : A fast machine learning-based application for human influenza A and B virus subtyping 

      Cacciabue, Marco Polo Domingo; Marcone, Débora Natalia (Wiley, 2023-01)
      Influenza viruses are one of the main agents causing acute respiratory infections (ARI) in humans resulting in a large amount of illness and death globally.1, 2 The influenza viruses classification is based on the nomenclature ...
    • SARS-CoV-2 RBD protein enhances the oncolytic activity of the vesicular stomatitis virus 

      Alkayyal, Almohanad A.; Ajina, Reham; Cacciabue, Marco Polo Domingo; Alkayyal, Aaesha A.; Saeedi, Nizar H.; Hussain Alshehry, Taofik; Kaboha, Feras; Alotaibi, Mohammed A.; Zaidan, Nada; Shah, Khalid; Alroqi, Fayhan; Bakur Mahmoud, Ahmad (Frontiers Media, 2023-01)
      Despite recent advances in the research on oncolytic viruses (OVs), a better understanding of how to enhance their replication is key to improving their therapeutic index. Understanding viral replication is important to ...
    • ViralPlaque: a Fiji macro for automated assessment of viral plaque statistics 

      Cacciabue, Marco Polo; Curra, Anabella Paola; Gismondi, Maria Ines (PeerJ, 2019-09)
      laque assay has been used for a long time to determine infectious titers and characterize prokaryotic and eukaryotic viruses forming plaques. Indeed, plaque morphology and dimensions can provide information regarding the ...