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Mostrando ítems 1-20 de 47
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A phenotypic characterization of two isolates of a multidrug-resistant outbreak strain of mycobacterium tuberculosis with opposite epidemiological fitness
Bei, Jinlong; Bigi, María Mercedes; Lima, Analía; Zhang, Qi; Blanco, Federico Carlos; López, Beatriz; Yu, Ting; Wang, Zhilin; Dai, Zhangyan; Chen, Zhuang; Cataldi, Angel Adrian; Sasiain, María del Carmen; Ritacco, Viviana; De la Barrera, Silvia Susana; Soria, Marcelo Abel; Durán, Rosario; Bigi, Fabiana (Hindawi, 2020-04)Tuberculosis (TB) is an infectious disease, caused by Mycobacterium tuberculosis, primarily affecting the lungs. The M. tuberculosis strain of the Haarlem family named M was responsible for a large multidrug-resistant TB ... -
An inhibitory mechanism of action of coiled‐coil peptides against type three secretion system from enteropathogenic Escherichia coli
Larzabal, Mariano; Baldoni, Hector A.; Suvire, Fernando D.; Curto, Lucrecia M.; Gomez, Gabriela E.; Marques Da Silva, Wanderson; Giudicessi, Silvana L.; Camperi, Silvia A.; Delfino, Jose M.; Cataldi, Angel Adrian; Enriz, Daniel (Wiley, 2019-03)Human pathogenic gram‐negative bacteria, such as enteropathogenic Escherichia coli (EPEC), rely on type III secretion systems (T3SS) to translocate virulence factors directly into host cells. The coiled‐coil domains present ... -
Analysing nonsynonymous mutations between two Mycobacterium bovis strains with contrasting pathogenic profiles
Bigi, María Mercedes; Vazquez, Cristina Lourdes; Castelão, Ana Beatriz C.; Garcia, Elizabeth Andrea; Cataldi, Angel Adrian; Jackson, Mary; McNeil, Michael; Soria, Marcelo Abel; Zumarraga, Martin Jose; Cabruja, Matias; Gago, Gabriela; Blanco, Federico Carlos; Nishibe, Christiane; Almeida Junior, Nalvo Franco de; Araujo, Flabio Ribeiro de; Bigi, Fabiana (Elsevier, 2019-12)Mycobacterium bovis (M. bovis) is the causative agent of bovine tuberculosis, a chronic infectious disease that can affect cattle, other domesticated species, wild animals and humans. This disease produces important economic ... -
Association between spoligotype-VNTR types and virulence of Mycobacterium bovis in cattle
Garbaccio, Sergio Gabriel; Macias, Analía; Shimizu, Ernesto; Paolicchi, Fernando; Pezzone, Natalia; Zapata, Laura; Abdala, Alejandro Ariel; Tarabla, Hector Dante; Peyru, Maite; Caimi, Karina Cynthia; Zumarraga, Martin Jose; Canal, Ana María; Cataldi, Angel Adrian; Magnano, Gabriel (Taylor & Francis, 2014-01)Mycobacterium bovis is the causative agent of bovine tuberculosis, a disease that affects approximately 5% of Argentine cattle. The aim of this research was to study if it is possible to infer the degree of virulence of ... -
BoLA-DRB3 exon2 polymorphisms among tuberculous cattle: Nucleotide and functional variability and their association with bovine tuberculosis pathology
Eirin, Maria Emilia; Carignano, Hugo Adrian; Shimizu, Ernesto; Pando, Maria de los Angeles; Zumarraga, Martin Jose; Magnano, Gabriel; Macías, Analía; Garbaccio, Sergio Gabriel; Huertas, Pablo Sebastian; Morsella, Claudia Graciela; Ferrara Muñiz, Ximena; Cataldi, Angel Adrian; Paolicchi, Fernando; Poli, Mario Andres (Elsevier, 2020-06)Bovine tuberculosis (bTB) is caused by Mycobacterium bovis and disseminated worldwide. In Argentina, the highest prevalence occurs in dairy areas. BoLA DRB3.2 is related to the adaptive immunity in mycobacterial infections. ... -
Bovine tuberculosis in domestic pigs: Genotyping and distribution of isolates in Argentina
Barandiaran, Soledad; Martinez Vivot, Marcela; Pérez, Andrés M.; Cataldi, Angel Adrian; Zumarraga, Martin Jose (Elsevier, 2015-12)Bovine tuberculosis is caused by Mycobacterium bovis and affects primarily cattle, among many other mammal species. In this study, 250 isolates of M. bovis collected from pigs slaughtered in Argentina were typed by ... -
Changes in hematological, biochemical, and blood gases prameters in response to progressive inclusion of nitrate in the diet of Holstein calves
Ortiz Chura, Abimael; Marcoppido, Gisela Ariana; Gere, José; Depetris, Gustavo; Stefañuk Bahamonde, Francisco José; Trangoni, Marcos David; Cravero, Silvio Lorenzo Pedro; Faverin, Claudia; Cataldi, Angel Adrian; Ceron Cucchi, Maria Esperanza (Veterinary World Publisher, 2021-01)Background and Aim: Nitrate (NO3-) reduces enteric methane emissions and could be a source of non-protein nitrogen in ruminant feeds. Nonetheless, it has a potential toxic effect that could compromise animal health and ... -
Characterization of Cellulolytic Activities of Environmental Bacterial Consortia from an Argentinian Native Forest
Romano, Nelson Gaston; Gioffre, Andrea; Sede, Silvana Mabel; Campos, Eleonora; Cataldi, Angel Adrian; Talia, Paola Mónica (Springer, 2013-08)Cellulolytic activities of three bacterial consortia derived from a forest soil sample from Chaco region, Argentina, were characterized. The phylogenetic analysis of consortia revealed two main highly supported groups ... -
Clade 8 and clade 6 strains of Escherichia coli O157:H7 from cattle in Argentina have Hypervirulent-Like phenotypes
Amigo, Natalia; Mercado, Elsa Cristina; Bentancor, Adriana Beatriz; Singh, Pallavi; Vilte, Daniel Alejandro; Gerhardt, Elizabeth; Zotta, Elsa; Ibarra, Cristina Adriana; Manning, Shannon D.; Larzabal, Mariano; Cataldi, Angel Adrian (PLOS, 2015-06-01)The hemolytic uremic syndrome (HUS) whose main causative agent is enterohemorrhagic Escherichia coli (EHEC) O157:H7 is a disease that mainly affects children under 5 years of age. Argentina is the country with the highest ... -
Comparative study of two deleted Mycobacterium bovis strains in experimental animal models
Ferrara Muñiz, Ximena; Blanco, Federico Carlos; Garcia, Elizabeth Andrea; Delgado, Fernando Oscar; Marfil, Maria Jimena; Zumarraga, Martin Jose; Cataldi, Angel Adrian; Eirin, Maria Emilia (European Society of Mycobacteriology, 2024-06)Introduction: Bovine tuberculosis (bTB) constitutes a problem for livestock and Public Health due to its negative impact on farms and its zoonotic nature. In Argentina, the application of the National Control and Eradication ... -
Detection of Mycobacterium bovis–infected dairy herds using PCR in bulk tank milk samples
Zumarraga, Martin Jose; Soutullo, Adriana; Garcia, Maria Ines; Marini, M. Rocío; Abdala, Alejandro Ariel; Tarabla, Hector Dante; Echaide, Susana T. de; Lopez, Marcela; Zervini, Elsa; Canal, Ana María; Cataldi, Angel Adrian (Mary Ann Liebert Inc., 2012-02)Bovine tuberculosis (bTB) is a chronic and zoonotic disease due to Mycobacterium bovis. The tuberculosis eradication campaign carried out in Argentina has considerably improved the health situation of the herds. Here we ... -
Draft genome sequence of Mycobacterium bovis 04-303, a highly virulent strain from Argentina
Nishibe, Christiane; Canevari Castelão, Ana Beatriz; Dalla Costa, Ricardo; Pinto, Beatriz Jeronimo; Varuzza, Leonardo; Cataldi, Angel Adrian; Bernardelli, Amelia; Bigi, Fabiana; Blanco, Federico Carlos; Zumarraga, Martin Jose; Almeida, Nalvo Franco; Araujo, Flabio Ribeiro de (American Society for Microbiology, 2013-11)Mycobacterium bovis strain 04-303 was isolated from a wild boar living in a free-ranging field in Argentina. This work reports the draft genome sequence of this highly virulent strain and the genomic comparison of its major ... -
Dynamics of the ruminal microbial ecosystem, and inhibition of methanogenesis and propiogenesis in response to nitrate feeding to Holstein calves
Ortiz Chura, Abimael; Gere, José; Marcoppido, Gisela Ariana; Depetris, Gustavo; Cravero, Silvio Lorenzo Pedro; Faverin, Claudia; Pinares-Patiño, Cesar; Cataldi, Angel Adrian; Ceron Cucchi, Maria Esperanza (Elsevier, 2021-12)It is known that nitrate inhibits ruminal methanogenesis, mainly through competition with hydrogenotrophic methanogens for available hydrogen (H2) and also through toxic effects on the methanogens. However, there is limited ... -
Early immune innate hallmarks and microbiome changes across the gut during Escherichia coli O157: H7 infection in cattle
Larzabal, Mariano; Marques Da Silva, Wanderson; Multani, Anmol; Vagnoni, Lucas Emilio; Moore, Prando Dadin; Marin, Maia Solange; Riviere, Nahuel Agustin; Delgado, Fernando Oscar; Vilte, Daniel Alejandro; Romero Victorica, Matias; Tao, Ma; Luo, Le Guan; Talia, Paola Mónica; Cataldi, Angel Adrian; Cobo, Eduardo Rubén (SpringerNature, 2020-12)The zoonotic enterohemorrhagic Escherichia coli (EHEC) O157: H7 bacterium causes diarrhea, hemorrhagic colitis, and hemolytic uremic syndrome (HUS) in humans. Cattle are primary reservoirs and EHEC O157: H7; the bacteria ... -
Efficacy of a recombinant Intimin, EspB and Shiga toxin 2B vaccine in calves experimentally challenged with Escherichia coli O157:H7
Martorelli, Luisina; Garimano, Nicolás; Fiorentino, Gabriela A.; Vilte, Daniel Alejandro; Garbaccio, Sergio Gabriel; Barth, Stefanie A.; Menge, Christian; Ibarra, Cristina Adriana; Palermo, Marina Sandra; Cataldi, Angel Adrian (Elsevier, 2018-06)Escherichia coli O157:H7 is a zoonotic pathogen of global importance and the serotype of Shiga toxin-producing E. coli (STEC) most frequently associated with Hemolytic Uremic Syndrome (HUS) in humans. The main STEC reservoir ... -
Ensayo interlaboratorio : aislamiento de Mycobacterium bovis a partir de lesiones granulomatosas en bovinos = Interlaboratory test: Isolation of Mycobacterium bovis from granulomatous lesions in bovine
Garbaccio, Sergio Gabriel; Barandiaran, Soledad; Fernández, Analía; Macias, Analía; Magnano, Gabriel; Martinez Vivot, Marcela; Peyru, Maite; Cataldi, Angel Adrian (2016)Mycobacterium bovis es el agente etiológico de la tuberculosis bovina. La confirmación diagnóstica en el laboratorio se realiza a través del aislamiento bacteriológico. Los ensayos interlaboratorio permiten evaluar el ... -
Enterohemorrhagic Escherichia coli O157:H7 antigens produced in transgenic lettuce effective as an oral vaccine in mice
Su, Yun‑Lin; Larzabal, Mariano; Song, Huan; Cheng, Tianfang; Wang, Yufang; Smith, Libia Yael; Cataldi, Angel Adrian; Ow, David W. (Springer, 2023-10)Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is a food-borne pathogen where ruminant farm animals, mainly bovine, serve as reservoirs. Bovine vaccination has been used to prevent disease outbreaks, and the current ... -
Evaluación de proteínas de una isla de patogenicidad y de envolturas bacterianas de Escherichia coli 0157:H7 como vacunas para reducir su incidencia en bovinos
Vilte, Daniel Alejandro (Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, 2015-11)Escherichia coli enterohemorrágico (EHEC) es un patógeno que puede causar diarrea, colitis hemorrágica, y síndrome urémico hemolítico (SUH), una enfermedad sistémica grave que afecta principalmente a los niños. En Argentina ... -
Fitness of drug resistant Mycobacterium tuberculosis and the impact on the transmission among household contacts
Morcillo, Nora; Imperiale, Belen Rocio; Di Giulio, Angela Beatríz; Zumarraga, Martin Jose; Takif, Howard; Cataldi, Angel Adrian (Elsevier, 2014-12)There has been an on-going debate on whether the development of drug resistance in Mycobacterium tuberculosis reduces its relative fitness and its ability to cause disease. The aim of this study was to explore this ... -
Genotyping Mycobacterium bovis from cattle in the Central Pampas of Argentina: tempoal and regional trends
Shimizu, Ernesto; Macias, Analía; Paolicchi, Fernando; Magnano, Gabriel; Zapata, Laura; Fernandez, Analía; Canal, Ana María; Garbaccio, Sergio Gabriel; Cataldi, Angel Adrian; Caimi, Karina Cynthia; Zumarraga, Martin Jose (Fundacao Oswaldo Cruz, Brasil, 2014-04)Mycobacterium bovis is the causative agent of bovine tuberculosis (TB), a disease that affects approximately 5% of Argentinean cattle. Among the molecular methods for genotyping, the most convenient are spoligotyping and ...