autores
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Mostrando ítems 1-17 de 17
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A simple and economic three-step process for producing highly purified Fab’ fragments directly from the egg yolk water-soluble fraction
González Viacava, Myriam Belén; Leiva, Carlos Leónidas; Tavarone, Maria Eugenia; Dokmetjian, José Christian; Cascone, Osvaldo; Chacana, Pablo; Fingermann, Matías (Elsevier, 2022-11)Although mammals are still the main source of polyclonal antibodies production, the use of egg yolk immunoglobulins (IgY) is increasing, and thus improvement of its safety to reduce undesired reactions is needed. Removal ... -
Bacteriological, serological, and histopathological study of post-weaning piglets experimentally infected with Salmonella Typhimurium = Estudio bacteriológico, serológico e histopatológico de lechones destetados infectados experimentalmente con Salmonella Typhimurium
Joaquim, Patricia Estefania; Balbiani, Facundo; Delgado, Fernando Oscar; Redondo, Leandro Martin; Cappuccio, Javier Alejandro; Chacana, Pablo (Facultad de Ciencias Veterinarias, Universidad Nacional del Nordeste, 2023-11)In the last decades, infections by several serovars of Salmonella have become relevant worldwide, not only due to their impact on veterinary health and animal production, but also because they may serve as a source of ... -
Brucella spp. Lumazine synthase as a novel immunomodulator to produce egg yolk antibodies
Bellido, Demian; Chacana, Pablo; Mozgovoj, Marina Valeria; Gonzalez, Diego; Goldbaum, Fernando Alberto; Wigdorovitz, Andres; Dus Santos, Maria Jose (Scientific Research, 2012-02)Lumazine synthase from Brucella spp. (BLS) is a highly immunogenic decameric protein. It has been previously described as a carrier of peptides or proteins to increase their immunogenicity in different animal species, but ... -
Chicken egg yolk antibodies against bovine respiratory syncytial virus neutralize the virus in vitro
Ferella, Alejandra; Bellido, Demian; Chacana, Pablo; Wigdorovitz, Andres; Dus Santos, Maria Jose; Mozgovoj, Marina Valeria (Elsevier, 2012)Bovine respiratory syncytial virus (BRSV) and its counterpart in humans (HRSV) are two closely related virus, which are the leading cause of severe respiratory syndrome in calves and young children, respectively. Passive ... -
Efficacy of chestnut and quebracho wood extracts to control Salmonella in poultry
Casanova, Natalia Andrea; Redondo, Leandro Martin; Redondo, Enzo Alejandro; Joaquim, Patricia Estefania; Dominguez, Johana Natali; Fernandez Miyakawa, Mariano Enrique; Chacana, Pablo (Wiley, 2021-07)Aims: The study was aimed to evaluate the antibacterial activity and efficacy of chestnut and quebracho wood extracts against Salmonella by in vitro assays and in vivo trials. Methods and results: The extracts showed ... -
First isolation of Salmonella enterica serovar Soerenga from pregnant sows in Argentina = Primer aislamiento de Salmonella enterica serovar Soerenga a partir de cerdas gestantes en Argentina
Joaquim, Patricia Estefania; Herrera, Mariana; Moroni, Mirian; Chacana, Pablo (Facultad de Ciencias Veterinarias, Universidad Nacional del Nordeste, 2024-05)The first isolation of Salmonella enterica serovar Soerenga in Argentina was obtained from stool samples of pregnant sows from intensive production in the province of La Pampa, Argentina, in February 2019. Biochemical ... -
IgY technology: producing antibodies from a 3Rs perspective
Leiva, Carlos Leónidas; Casanova, Natalia Andrea; Fernandez Miyakawa, Mariano Enrique; Chacana, Pablo (2018-07) -
IgY-based antivenom against Bothrops alternatus: Production and neutralization efficacy
Leiva, Carlos Leónidas; Cangelosi, Adriana; Mariconda, Virginia; Farace, Mariano; Geoghegan, Patricia; Brero, Luisa; Fernandez Miyakawa, Mariano Enrique; Chacana, Pablo Anibal (Elsevier, 2019-05)Antivenom for the treatment of bothropic snakebite is a priority for public health institutions from Latin America. An alternative to the conventional antivenom production is based on the use of egg yolk antibodies – ... -
IgY-technology (egg yolk antibodies) in human medicine: a review of patents and clinical trials
Leiva, Carlos; Gallardo, Mauro Julián; Casanova, Natalia Andrea; Terzolo, Horacio; Chacana, Pablo (Elsevier, 2020-04)IgY-technology (the production and extraction of specific IgY antibodies from egg yolk) is an innovative method to produce antibodies for therapy and prophylaxis. Advantages of IgY over other antibodies comprise its ... -
In vitro inhibitory activity of IgY antibodies against Salmonella ser. newport isolated from horses
Bustos, Carla Paola; Leiva, Carlos Leónidas; Gambarotta, Mariana; Guida, Nora; Chacana, Pablo (Elsevier, 2021-08)Equine salmonellosis is caused by several Salmonella serotypes, including Salmonella Newport, which cause enterocolitis and diarrhea. Treatment usually includes the administration of antibiotics. However, since multidrug-resistant ... -
In vivo neutralization of bee venom lethality by IgY antibodies
Leiva, Carlos Leónidas; Geoghegan, Patricia; Lammer, Mónica; Cangelosi, Adriana; Mariconda, Virginia; Celi Castillo, Ana Beatriz; Brero, Luisa; Chacana, Pablo (Elsevier, 2021-07)Bee venom is a complex mixture of molecules, among which melittin and phospholipase A2 (PLA2) are the toxic components involved in envenoming accidents with multiple honeybee stings. Traditionally, the treatment of envenomings ... -
Molecular characterization and antimicrobial resistance profiles of Salmonella Heidelberg isolates from poultry
Dominguez, Johanna Elizabeth; Viñas, María Rosa; Herrera, Mariana; Moroni, Mirian; Gutkind, Gabriel Omar; Mercado, Elsa Cristina; Di Conza, José Alejandro; Chacana, Pablo (Wiley, 2021-02)In the last 10 years, Salmonella Heidelberg has been extensively isolated from poultry in several countries. In this context, molecular characterization is essential to understand whether the strains have entered the farms ... -
Rats as sources of multidrug-resistant Enterobacteriaceae in animal production environments
Dominguez, Johanna Elizabeth; Lovera, Rosario; Sánchez, Juliana; Redondo, Leandro Martin; Chacana, Pablo; Cavia, Regino; Fernandez Miyakawa, Mariano Enrique (Wiley, 2023-07)Rattus norvegicus and Rattus rattus are commensal pest rodents, considered reservoirs and vectors of zoonotic pathogens. In livestock farms, the wide use of antimicrobials and their release into the environment lead to ... -
Reproducción experimental de la infección de Eimeria spp. en pollos parrilleros a partir de un aislamiento de campo
Tomazic, Mariela Luján; Delgado, Fernando Oscar; Balbiani, Facundo; Jauregui, Gloria R.; Chacana, Pablo; Schapiro, Javier Hernan; De Franceschi, M.; Palacios, L.; Rodriguez, Anabel Elisa (FundaVet, 2019-06)La coccidiosis es la afección parasitaria de mayor trascendencia económica en explotaciones avícolas. La producen protozoarios del género Eimeria que afectan el intestino delgado y los ciegos de las aves. Su control se ... -
Simultaneous carriage of mcr-1 and other antimicrobial resistance determinants in Escherichia coli from poultry
Dominguez, Johanna Elizabeth; Redondo, Leandro Martín; Figueroa Espinosa, Roque A.; Cejas, Daniela; Gutkind, Gabriel Omar; Chacana, Pablo; Di Conza, José Alejandro; Fernandez Miyakawa, Mariano Enrique (Frontiers Media, 2018-07)The use of antimicrobial growth promoters (AGPs) in sub-therapeutic doses for long periods promotes the selection of resistant microorganisms and the subsequent risk of spreading this resistance to the human population and ... -
Use of adjuvant ISA VG 71 to produce neutralizing egg yolk antibodies against bothropic venom
Leiva, Carlos Leónidas; Cangelosi, Adriana; Mariconda, Virginia; Celi Castillo, Ana Beatriz; Joaquim, Patricia Estefania; Geoghegan, Patricia; Fernandez Miyakawa, Mariano Enrique; Chacana, Pablo (Springer, 2023-02)The use of egg yolk antibodies—IgY technology—represents an alternative to the production of mammalian immunoglobulins and has several advantages regarding animal welfare and lower costs of production. The use of adjuvants ... -
Virulence genes and antimicrobial susceptibility in Salmonella enterica serotypes isolated from swine production in Argentina = Genes de virulencia y sensibilidad a antimicrobianos en serotipos de Salmonella enterica aislados de producción porcina en Argentina
Joaquim, Patricia Estefania; Herrera, Mariana; Dupuis, Alberto; Chacana, Pablo (Elsevier, 2021)Salmonella is a worldwide-distributed pathogen that affects both humans and animals and is usually associated with intensive animal production such as poultry and swine. This bacterium carries different virulence genes, ...