• Development of nanobodies against Mal de Río Cuarto virus major viroplasm protein P9‑1 for diagnostic sandwich ELISA and immunodetection 

      Llauger, Gabriela; Monti, Demian Esteban; Aduriz Guerrero, Matías; Romão, Ema; Dumon, Analia Delina; Mattio, Maria Fernanda; Wigdorovitz, Andres; Muyldermans, Serge; Vincke, Cécile; Parreño, Viviana; Del Vas, Mariana (Springer Nature, 2021-10)
      Mal de Río Cuarto virus (MRCV) is a member of the genus Fijivirus of the family Reoviridae that causes a devastating disease in maize and is persistently and propagatively transmitted by planthopper vectors. Virus replication ...
    • Live attenuated Mycobacterium bovis strains combined with the encapsulated H65 antigen as a vaccine strategy against bovine tuberculosis in a mouse model 

      Onnainty, Renée; Marini, M. Rocío; Gravisaco, María José; Garcia, Elizabeth Andrea; Aagaard, Claus; Canal, Ana María; Granero, Gladys; Bigi, Fabiana; Blanco, Federico Carlos (Elsevier, 2024-04)
      Mycobacterium bovis is an etiological agent of bovine tuberculosis (bTB) that also infects other mammals, including humans. The lack of an effective vaccine for the control of bTB highlights the need for developing new ...
    • Nanofertilizantes no cultivo do milho safrinha 

      Guerra da Silva, Alessandro; Ciacci, María Belén; Dias Batista Silva, Nathália; Giachero, María Lorena; Serri, Dannae Lilia; Rosa, Márcio; Silva Simões, Geovanna (ABMS Associação Brasileira de Milho e Sorgo, 2023-11-28)
      Nos últimos anos, novas tecnologias têm surgido como forma de adoção nos sistemas de cultivo de milho safrinha visando aumentos de produtividade de grãos. Neste contexto, destaca-se o uso de novas formulações de fertilizantes, ...
    • SARS-CoV-2 specific nanobodies neutralize different variants of concern and reduce virus load in the brain of h-ACE2 transgenic mice 

      Pavan, Florencia; Bok, Marina; Betanzos San Juan, Rafael; Malito, Juan Pablo; Marcoppido, Gisela Ariana; Franco, Diego Rafael; Militelo, Daniela Ayelen; Schammas, Juan Manuel; Bari, Sara Elizabeth; Stone, William B.; López, Krisangel; Porier, Danielle LaBrie; Muller, John Anthony; Auguste, Albert J.; Yuan, Lijuan; Wigdorovitz, Andres; Parreño, Gladys Viviana; Ibañez, Lorena Itat (MDPI, 2024-02)
      Since the beginning of the COVID-19 pandemic, there has been a significant need to develop antivirals and vaccines to combat the disease. In this work, we developed llama-derived nanobodies (Nbs) directed against the ...