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Ivermectin antiviral activity against Varicellovirus bovinealpha 1: assessment of intracellular drug accumulation in virus‑infected cells
Pérez, Sandra; Miró, María Victoria; Verna, Andrea Elizabeth; González Altamiranda, Erika; Barcos, Oscar; Lanusse, Carlos Edmundo; Lifschitz, Adrián Luis (Springer, 2024-01)Varicellovirus bovinealpha 1 (formerly bovine alphaherpesvirus type 1, BoAHV-1) is associated with several syndromes in cattle, including respiratory disease and is one of the main agents involved in the bovine respiratory ... -
Macrocyclic lactones and ectoparasites control in livestock: efficacy, drug resistance and therapeutic challenges
Lifschitz, Adrian Luis; Nava, Santiago; Miró, María Victoria; Canton, Candela; Alvarez, L.; Lanusse, Carlos Edmundo (Elsevier, 2024-08)Macrocyclic lactones (MLs) are the cornerstone of parasite control in livestock due to their broad-spectrum activity against endo (nematodes) and ecto (lice, ticks, mites) parasites. These molecules, introduced into the ... -
Phytochemicals in Gastrointestinal Nematode Control: Pharmacokinetic–Pharmacodynamic Evaluation of the Ivermectin plus Carvone Combination
Miró, María Victoria; Costa Júnior, Livio M.; Lloberas, María Mercedes; Cardozo, Patricia Alejandra; Lanusse, Carlos; Virkel, Guillermo; Lifschitz, Adrián (Multidisciplinary Digital Publishing Institute, MDPI, 2023-04)A wide variety of plant-derived phytochemicals with anthelmintic effects have been described. Most of them have shown activity against parasites in vitro but have not been extensively explored in vivo. The aim of the current ... -
Relationship between pharmacokinetics of fluazuron and its efficacy for controlling Rhipicephalus microplus: A comprehensive evaluation of tick drug uptake
Sarli, Macarena; Miró, María Victoria; Rossner, Maria Victoria; Gomez, Viviana Daniela; Torrents, Jorgelina; Nava, Santiago; Lifschitz, Adrián Luis (Elsevier, 2024-11)Relationship between fluazuron (FZN) concentrations in cattle plasma and ticks and its therapeutic efficacy percentage (EP) against Rhipicephalus microplus was analyzed. The extent of FZN uptake by ticks after its topical ...