• A simple and economic three-step process for producing highly purified Fab’ fragments directly from the egg yolk water-soluble fraction 

      González Viacava, Myriam Belén; Leiva, Carlos Leónidas; Tavarone, Maria Eugenia; Dokmetjian, José Christian; Cascone, Osvaldo; Chacana, Pablo; Fingermann, Matías (Elsevier, 2022-11)
      Although mammals are still the main source of polyclonal antibodies production, the use of egg yolk immunoglobulins (IgY) is increasing, and thus improvement of its safety to reduce undesired reactions is needed. Removal ...
    • Expression and purification of recombinant feline interferon in the baculovirus-insect larvae system 

      Targovnik, Alexandra Marisa; Villaverde, Marcela Solange; Arregui, Mariana Bernadett; Fogar, Mariela Noemi; Taboga, Oscar Alberto; Glikin, Gerardo Claudio; Finocchiaro, Liliana Maria Elena; Cascone, Osvaldo; Miranda, Maria Victoria (2014-06)
      Feline interferons (FeIFNs) are cytokines with antiviral, antitumor and immunomodulatory functions used as therapeutic agents in a variety of veterinary diseases. In this work, FeIFN-α7 and FeIFN-α7xArg containing eight ...
    • Rapid and cost-effective process based on insect larvae for scale-up production of SARS-COV-2 spike protein for serological COVID-19 testing 

      Smith, Ignacio; Mc Callum, Gregorio Juan; Sabljic, Adriana Victoria; Marfia, Juan Ignacio; Bombicino, Silvina Sonia; Trabucchi, Aldana; Iacono, Ruben Francisco; Birenbaum, Joaquín Manuel; Vazquez, Susana Claudia; Minoia, Juan Mauricio; Cascone, Osvaldo; Lopez, Maria Gabriela; Taboga, Oscar Alberto; Targovnik, Alexandra Marisa; Wolman, Federico Javier; Fingermann, Matías; Alonso, Leonardo Gabriel; Valdez, Silvina Noemí; Miranda, María Victoria (Wiley, 2021-10)
      Serology testing for COVID-19 is important in evaluating active immune response against SARS-CoV-2, studying the antibody kinetics, and monitoring reinfections with genetic variants and new virus strains, in particular, ...