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CRISPR/Cas9 and genetic screens in malaria parasites : small genomes, big impact
Ishizaki, Takahiro; Hernandez, Sophia; Paoletta, Martina; Sanderson, Theo; Bushell, Ellen S. C. (Portland Press, 2022-06)The ∼30 Mb genomes of the Plasmodium parasites that cause malaria each encode ∼5000 genes, but the functions of the majority remain unknown. This is due to a paucity of functional annotation from sequence homology, which ...