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Comparative tissue pharmacokinetics and efficacy of moxidectin, abamectin and ivermectin in lambs infected with resistant nematodes: Impact of drug treatments on parasite P-glycoprotein expression
Lloberas, María Mercedes; Alvarez, Luis Ignacio; Entrocasso, Carlos; Virkel, Guillermo Leon; Ballent, Mariana; Maté, María Laura; Lanusse, Carlos Edmundo; Lifschitz, Adrian Luis (Elsevier, 2013-12)The high level of resistance to the macrocyclic lactones has encouraged the search for strategies to optimize their potential as antiparasitic agents. There is a need for pharmaco-parasitological studies addressing the ... -
Doramectin efficacy against Psoroptes ovis in sheep: Evaluation of pharmacological strategies
Larroza, Marcela Patricia; Soler, Paula; Robles, Carlos Alejandro; Cabrera, Francisco Raúl; Ballent, Mariana; Lanusse, Carlos; Lifschitz, Adrian Luis (Elsevier, 2020-11)The aims of this study were to evaluate the efficacy of two injectable formulations of doramectin (DRM) against Psoroptes ovis in sheep infested under controlled experimental conditions and to characterize the DRM plasma ... -
Eprinomectin accumulation in Rhipicephalus (Boophilus) microplus : pharmacokinetic and efficacy assessment
Lifschitz, Adrian Luis; Nava, Santiago; Mangold, Atilio Jose; Imperiale, Fernanda Andrea; Ballent, Mariana; Canevari, Jose Tobias; Lanusse, Carlos Edmundo (2016-01)Eprinomectin (EPM) is a macrocyclic lactone used against endo-ectoparasites without withdrawal time in milk and meat after its pour-on administration at 0.5 mg/kg. Previous experiments evaluated the efficacy of EPM against ... -
Evaluación de la eficacia de antisárnicos contra Psoroptes ovis en ovinos
Larroza, Marcela Patricia; Soler, Paula; Robles, Carlos Alejandro; Martinez, Agustin; Cabrera, Francisco Raul; Canton, Candela; Ballent, Mariana; Lanusse, Carlos Edmundo; Lifschitz, Adrian Luis (EEA Bariloche, INTA, 2021-02)En el presente informe técnico se describen los principales resultados obtenidos en estudios de eficacia de formulaciones inyectables de ivermectina (IVM) y doramectina (DRM) contra Psoroptes ovis en ovinos infestados ... -
Relationship between pharmacokinetics of ivermectin (3.15%) and its efficacy to control the infestation with the tick Rhipicephalus (Boophilus) microplus in cattle
Nava, Santiago; Rossner, Maria Victoria; Ballent, Mariana; Mangold, Atilio Jose; Lanusse, Carlos Edmundo; Lifschitz, Adrian Luis (Elsevier, 2019-04)This study aimed to determine the relationship between the variation in plasma concentration of ivermectin 3.15% over time and its efficacy against the cattle tick Rhipicephalus (Boophilus) microplus. In addition, a trial ...