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Detection, molecular characterization and phylogenetic analysis of G3P[12] and G14P[12] equine rotavirus strains co-circulating in central Kentucky
Carossino, Mariano; Barrandeguy, Maria Edith; Li, Yanqiu; Parreño, Viviana; Janes, Jennifer; Loynachan, Alan T.; Balasuriya, Udeni B.R. (Elsevier, 2018)Equine rotavirus A (ERVA) is the leading cause of diarrhea in neonatal foals and a major health problem to the equine breeding industry worldwide. The G3P[12] and G14P[12] ERVA genotypes are the most prevalent in foals ... -
Development and evaluation of a one-step multiplex real-time TaqMan® RT-qPCR assay for the detection and genotyping of equine G3 and G14 rotaviruses in fecal samples
Carossino, Mariano; Barrandeguy, Maria Edith; Erol, Erdal; Li, Yanqiu; Balasuriya, Udeni B.R. (BMC, 2019-04)Background: Equine rotavirus A (ERVA) is the leading cause of diarrhea in neonatal foals and has a negative impact on equine breeding enterprises worldwide. Among ERVA strains infecting foals, the genotypes G3P[12] and ... -
Development of recombinant VHH nanobodies as an alternative for clearance of equine arteritis virus in carrier stallions
Aduriz Guerrero, Matías; Carossino, Mariano; Go, Y.Y.; Vincke, Cécile; Balasuriya, Udeni B.R.; Muyldermans, S.; Wigdorovitz, Andres; Barrandeguy, Maria Edith; Parreño, Viviana (2016)In conclusion, a VHH library derived from llama B cells following immunization with EAV was generated. This novel strategy could allow the generation of EAV-specific neutralizing Nbs as a therapeutic approach to induce ... -
Equine rotavirus a under the one health lens : potential impacts on public health
Carossino, Mariano; Vissani, Maria Aldana; Barrandeguy, Maria Edith; Balasuriya, Udeni B.R.; Parreño, Gladys Viviana (MDPI, 2024-01)Group A rotaviruses are a well-known cause of viral gastroenteritis in infants and children, as well as in many mammalian species and birds, affecting them at a young age. This group of viruses has a double-stranded, ... -
Quadruplex real-time TaqMan® RT-qPCR assay for differentiation of equine group A and B rotaviruses and Identification of group A G3 and G14 genotypes
Carossino, Mariano; Balasuriya, Udeni B.R.; Thieulent, Côme J.; Barrandeguy, Maria Edith; Vissani, Maria Aldana; Parreño, Gladys Viviana (MDPI, 2023-07)Equine rotavirus A (ERVA) is the leading cause of diarrhea in foals, with G3P[12] and G14P[12] genotypes being the most prevalent. Recently, equine G3-like RVA was recognized as an emerging infection in children, and a ... -
Rapid detection of equine infectious anaemia virus nucleic acid by insulated isothermal RT-PCR assay to aid diagnosis under field conditions
Cook, R.F.; Barrandeguy, Maria Edith; Lee, Pei-Yu Alison; Tsai, Chuan-Fu; Shen, Yu-Han; Tsai, Yun-Long; Chang, Hsiao-Fen G.; Wang, Hwa-Tang Thomas; Balasuriya, Udeni B.R. (Wiley, 2018)Background: Control of equine infectious anaemia (EIA) currently depends on serological diagnosis of infected equids. However, recently infected equids may not produce detectable anti-EIAV antibodies up to 157 days post ...