Now showing items 41-60 of 316

    • Mycobacterium intracellulare infection in a capybara (Hydrochoerus hydrochaeris) 

      Pezzone, Natalia; Eberhardt, Ayelén; Fernandez, Analía; Garbaccio, Sergio Gabriel; Zumarraga, Martin Jose; Gioffre, Andrea; Magni, Carolina; Beldomenico, Pablo Martín; Marini, M. Rocío; Canal, Ana María (American Association of Zoo Veterinarians, 2013-12)
      This report describes the first case of Mycobacterium intracellulare infection with typical granulomatous lesions of mycobacteriosis in a capybara (Hydrochoerus hydrochaeris). The individual was a captive-bred young female, ...
    • TMV-Cg Coat Protein stabilizes DELLA proteins and in turn negatively modulates salicylic acid-mediated defense pathway during Arabidopsis thaliana viral infection 

      Rodriguez, Maria Cecilia; Conti, Gabriela; Zavallo, Diego; Manacorda, Carlos Augusto; Asurmendi, Sebastian (2014)
      Background Plant viral infections disturb defense regulatory networks during tissue invasion. Emerging evidence demonstrates that a significant proportion of these alterations are mediated by hormone imbalances. Although ...
    • Identification of candidate genes associated with leaf senescence in cultivated sunflower (Helianthus annuus L.) 

      Moschen, Sebastian; Bengoa Luoni, Sofia Ailin; Paniego, Norma Beatriz; Hopp, Horacio Esteban; Dosio, Guillermo Aníbal Adrián; Fernandez, Paula Del Carmen; Heinz, Ruth Amelia (PLOS, 2014)
      Cultivated sunflower (Helianthus annuus L.), an important source of edible vegetable oil, shows rapid onset of senescence, which limits production by reducing photosynthetic capacity under specific growing conditions. ...
    • Genome-wide data (ChIP-seq) enabled identification of cell wall-related and aquaporin genes as targets of tomato ASR1, a drought stress-responsive transcription factor 

      Ricardi, Martiniano María; González, Rodrigo Matías; Silin, Zhong; Dominguez, Pia Guadalupe; Duffy, Tomas; Turjanski, Pablo Guillermo; Salgado Salter, Juan David; Alleva, Karina Edith; Carrari, Fernando; Giovannoni, James J.; Estevez, Jose Manuel; Iusem, Norberto Daniel (BMC, 2014-01)
      Background: Identifying the target genes of transcription factors is important for unraveling regulatory networks in all types of organisms. Our interest was precisely to uncover the spectrum of loci regulated by a widespread ...
    • The P0 protein encoded by cotton leafroll dwarf virus (CLRDV) inhibits local but not systemic RNA silencing 

      Delfosse, Veronica Cecilia; Agrofoglio, Yamila Carla; Casse, Maria Florencia; Bonacic Kresic, Iván; Hopp, Horacio Esteban; Ziegler-Graff, Véronique; Distefano, Ana Julia (2014-02)
      Plants employ RNA silencing as a natural defense mechanism against viruses. As a counter-defense, viruses encode silencing suppressor proteins (SSPs) that suppress RNA silencing. Most, but not all, the P0 proteins encoded ...
    • Silencing of the tomato Sugar Partitioning Affecting protein (SPA) modifies sink strength through a shift in leaf sugar metabolism 

      Bermudez Salazar, Luisa; de Godoy, Fabiana; Baldet, Pierre; Demarco, Diego; Osorio, Sonia; Quadrana, Leandro Daniel; Almeida de Souza, Juliana Beatriz; Asis, Ramón; Gibon, Yves; Fernie, Alisdair R.; Rossi, Maria Magdalena; Carrari, Fernando (Wiley; Society for Experimental Biology, 2014-03)
      Limitations in our understanding about the mechanisms that underlie source-sink assimilate partitioning are increasingly becoming a major hurdle for crop yield enhancement via metabolic engineering. By means of a ...
    • Immunogenicity of hypothetical highly conserved proteins as novel antigens in Anaplasma marginale 

      Nuñez, Pablo Alfredo; Moretta, Rosalia Ester; Ruybal, Paula; Wilkowsky, Silvina Elizabeth; Farber, Marisa Diana (Springer, 2014-03)
      Anaplasma marginale is a tick-transmitted Gram-negative intraerythrocytic bacterium and the etiological agent of bovine Anaplasmosis. Even though considerable research efforts have been undertaken, Anaplasmosis vaccine ...
    • Purification and characterization of a GH43 β-xylosidase from Enterobacter sp. identified and cloned from forest soil bacteria 

      Campos, Eleonora; Negro Alvarez, María José; Sabaris Di Lorenzo, Gonzalo Julián; Gonzalez, Sergio Alberto; Rorig, Marcela Laura; Talia, Paola Mónica; Grasso, Daniel Horacio; Sáez, Felicia; Manzanares Secades, Paloma; Ballesteros Perdices, Mercedes; Cataldi, Angel Adrian (Elsevier, 2014-03)
      The use of lignocellulosic biomass for second generation biofuels requires optimization of enzymatic breakdown of plant cell walls. In this work, cellulolytic bacteria were isolated from a native and two cultivated forest ...
    • Detection of Mycobacterium bovis in Bovine and Bubaline tissues using Nested-PCR for TbD1 

      Araújo, Cristina Pires de; Osório, Ana Luiza Alves Rosa; Jorge, Klaudia dos Santos Goncalves; Ramos, Carlos Alberto N.; Filho, Antonio Francisco S.; Vidal, Carlos Eugênio Soto; Roxo, Eliana; Nishibe, Christiane; Almeida Junior, Nalvo Franco de; Júnior, Antônio A. F.; Silva, Marcio Roberto; Neto, Jose Diomedes Barbosa; Cerqueira, Valíria Duarte; Zumarraga, Martin Jose; Araujo, Flabio Ribeiro de (PLOS, 2014-03)
      In the present study, a nested-PCR system, targeting the TbD1 region, involving the performance of conventional PCR followed by real-time PCR, was developed to detect Mycobacterium bovis in bovine/bubaline tissue homogenates. ...
    • Artificial microRNAs as antiviral strategy to FMDV: structural implications of target selection 

      Gismondi, Maria Ines; Ortiz, Xoana P.; Curra, Anabella Paola; Asurmendi, Sebastian; Taboga, Oscar Alberto (2014-04)
      RNA interference (RNAi) appears as a promising strategy to control virus replication. While the antiviral power of short-hairpin RNAs or small-interfering RNAs against FMDV has been demonstrated widely, safer RNAi effectors ...
    • Improving clustering with metabolic pathway data 

      Milone, Diego Humberto; Stegmayer, Georgina; Lopez, Mariana Gabriela; Kamenetzky, Laura; Carrari, Fernando (BMC, 2014-04)
      Background: It is a common practice in bioinformatics to validate each group returned by a clustering algorithm through manual analysis, according to a-priori biological knowledge. This procedure helps finding functionally ...
    • Natural occurring epialleles determine vitamin E accumulation in tomato fruits 

      Quadrana, Leandro Daniel; Almeida de Souza, Juliana Beatriz; Asis, Ramón; Duffy, Tomas; Dominguez, Pia Guadalupe; Bermudez Salazar, Luisa; Conti, Gabriela; Silva, Junia V. Corrêa da; Peralta, Iris Edith; Colot, Vincent; Asurmendi, Sebastian; Fernie, Alisdair R.; Rossi, Magdalena; Carrari, Fernando Oscar (2014-07)
      Vitamin E (VTE) content is a low heritability nutritional trait for which the genetic determinants are poorly understood. Here, we focus on a previously detected major tomato VTE quantitative trait loci (QTL; mQTL9-2-6) ...
    • Pre-columbian mycobacterial genomes reveal seals as a source of new world human tuberculosis 

      Bos, Kirsten I.; Harkins, Kelly M.; Herbig, Alexander; Coscolla, Mireia; Weber, Nico; Comas, Iñaki; Forrest, Stephen A.; Bryant, Josephine M.; Harris, Simon R.; Schuenemann, Verena J.; Campbell, Tessa J.; Majander, Kerrtu; Wilbur, Alicia K.; Guichon, Ricardo A.; Steadman, Dawnie L. Wolfe; Cook, Della Collins; Niemann, Stefan; Behr, Marcel A.; Zumarraga, Martin Jose; Bastida, Ricardo; Huson, Daniel; Nieselt, Kay; Young, Douglas; Parkhill, Julian; Buikstra, Jane E.; Gagneux, Sebastien; Stone, Anne C.; Krause, Johannes (Springer Nature, 2014-08)
      Modern strains of Mycobacterium tuberculosis from the Americas are closely related to those from Europe, supporting the assumption that human tuberculosis was introduced post-contact1. This notion, however, is incompatible ...
    • Experimental selection of long‐term intracellular mycobacteria 

      Vazquez, Cristina Lourdes; Lerner, Thomas R.; Kasmapour, Bahram; Pei, Gang; Gronow, Achim; Bianco, María Veronica; Blanco, Federico Carlos; Bleck, Christopher K.E.; Geffers, Robert; Bigi, Fabiana; Abraham, Wolf-Rainer; Gutierrez, Maximiliano Gabriel (Wiley, 2014-09)
      Some intracellular bacteria are known to cause long‐term infections that last decades without compromising the viability of the host. Although of critical importance, the adaptations that intracellular bacteria undergo ...
    • The genome of the stress-tolerant wild tomato species Solanum pennellii 

      Bolger, Anthony; Scossa, Federico; Bolger, Marie E.; Lanz, Christa; Maumus, Florian; Tohge, Takayuki; Quesneville, Hadi; Alseekh, Saleh; Sørensen, Iben; Lichtenstein, Gabriel; Fich, Eric A.; Conte, Mariana; Keller, Heike; Schneeberger, Korbinian; Schwacke, Rainer; Ofner, Itai; Vrebalov, Julia; Xu, Yimin; Osorio, Sonia; Aflitos, Saulo Alves; Schijlen, Elio; Jiménez-Goméz, José M.; Ryngajllo, Malgorzata; Kimura, Seisuke; Kumar, Ravi; Koenig, Daniel; Headland, Lauren R.; Maloof, Julin N.; Sinha, Neelima; van Ham, Roeland C. H. J.; Lankhorst, René Klein; Mao, Linyong; Vogel, Alexander; Arsova, Borjana; Panstruga, Ralph; Fei, Zhangjun; Rose, Jocelyn K. C.; Zamir, Dani; Carrari, Fernando; Giovannoni, James J.; Weigel, Detlef; Usadel, Björn; Fernie, Alisdair R. (Nature Publishing Group, 2014-09)
      Solanum pennellii is a wild tomato species endemic to Andean regions in South America, where it has evolved to thrive in arid habitats. Because of its extreme stress tolerance and unusual morphology, it is an important ...
    • Tomato Abscisic Acid Stress ripening (ASR) gene family revisited 

      Golan, Ido; Dominguez, Pia Guadalupe; Konrad, Zvia; Shkolnik Inbar, Doron; Carrari, Fernando; Bar Zvi, Dudy (PLOS, 2014-10-13)
      Tomato ABSCISIC ACID RIPENING 1 (ASR1) was the first cloned plant ASR gene. ASR orthologs were then cloned from a large number of monocot, dicot and gymnosperm plants, where they are mostly involved in response to abiotic ...
    • Double-layered rotavirus-like particles are efficient carriers to elicit strong CTL responses to delivered heterologous antigens 

      Molinari, Maria Paula; Peralta, Andrea Veronica; Maletto, Belkys Angélica; Pistoresi Palencia, Maria Cristina; Crespo, Maria Ines; Moron, Victor Gabriel; Taboga, Oscar Alberto (Elsevier, 2014-11)
      The first 92 amino acids of VP2 of rotavirus are dispensable for VLP assembly and can be replaced by heterologous reporter proteins without affecting either self-assembly of chimeric VP2 or the interaction with VP6 to ...
    • IFNG-mediated immune responses enhance autophagy against Mycobacterium tuberculosis antigens in patients with active tuberculosis 

      Rovetta, Ana Inés; Peña, Delfina; Hernández del Pino, Rodrigo Emanuel; Recalde, Gabriela María; Pellegrini, Joaquín Miguel; Bigi, Fabiana; Musella, Rosa María; Palmero, Domingo; Gutierrez, Marisa; Colombo, Maria Isabel; García, Verónica Edith (Taylor & Francis, 2014-11)
      Protective immunity against Mycobacterium tuberculosis (Mtb) requires IFNG. Besides, IFNG-mediated induction of autophagy suppresses survival of virulent Mtb in macrophage cell lines. We investigated the contribution of ...
    • Lipoxygenase activation in peanut seed cultivars resistant and susceptible to Aspergillus parasiticus colonization 

      Muller, Virginia; Amé, María Valeria; Carrari, Fernando; Gieco, Jorge Omar; Asis, Ramón (American Phytopathological Society, 2014-12)
      Accumulative evidence indicates that the lipoxygenase (LOX) pathway plays a significant role in the Aspergillus–seed interaction, such as interfering with activities of endogenous fungal oxylipins or producing antimicrobial ...
    • Fitness of drug resistant Mycobacterium tuberculosis and the impact on the transmission among household contacts 

      Morcillo, Nora; Imperiale, Belen Rocio; Di Giulio, Angela Beatríz; Zumarraga, Martin Jose; Takif, Howard; Cataldi, Angel Adrian (Elsevier, 2014-12)
      There has been an on-going debate on whether the development of drug resistance in Mycobacterium tuberculosis reduces its relative fitness and its ability to cause disease. The aim of this study was to explore this ...