Now showing items 1-6 of 6

    • Brucella spp. Lumazine synthase as a novel immunomodulator to produce egg yolk antibodies 

      Bellido, Demian; Chacana, Pablo; Mozgovoj, Marina Valeria; Gonzalez, Diego; Goldbaum, Fernando Alberto; Wigdorovitz, Andres; Dus Santos, Maria Jose (Scientific Research, 2012-02)
      Lumazine synthase from Brucella spp. (BLS) is a highly immunogenic decameric protein. It has been previously described as a carrier of peptides or proteins to increase their immunogenicity in different animal species, but ...
    • Chicken egg yolk antibodies against bovine respiratory syncytial virus neutralize the virus in vitro 

      Ferella, Alejandra; Bellido, Demian; Chacana, Pablo; Wigdorovitz, Andres; Dus Santos, Maria Jose; Mozgovoj, Marina Valeria (Elsevier, 2012)
      Bovine respiratory syncytial virus (BRSV) and its counterpart in humans (HRSV) are two closely related virus, which are the leading cause of severe respiratory syndrome in calves and young children, respectively. Passive ...
    • IgY technology: producing antibodies from a 3Rs perspective 

      Leiva, Carlos Leónidas; Casanova, Natalia Andrea; Fernandez Miyakawa, Mariano Enrique; Chacana, Pablo (2018-07)
    • IgY-based antivenom against Bothrops alternatus: Production and neutralization efficacy 

      Leiva, Carlos Leónidas; Cangelosi, Adriana; Mariconda, Virginia; Farace, Mariano; Geoghegan, Patricia; Brero, Luisa; Fernandez Miyakawa, Mariano Enrique; Chacana, Pablo Anibal (Elsevier, 2019-05)
      Antivenom for the treatment of bothropic snakebite is a priority for public health institutions from Latin America. An alternative to the conventional antivenom production is based on the use of egg yolk antibodies – ...
    • IgY-technology (egg yolk antibodies) in human medicine: a review of patents and clinical trials 

      Leiva, Carlos; Gallardo, Mauro Julián; Casanova, Natalia Andrea; Terzolo, Horacio; Chacana, Pablo (Elsevier, 2020-04)
      IgY-technology (the production and extraction of specific IgY antibodies from egg yolk) is an innovative method to produce antibodies for therapy and prophylaxis. Advantages of IgY over other antibodies comprise its ...
    • In vivo neutralization of bee venom lethality by IgY antibodies 

      Leiva, Carlos Leónidas; Geoghegan, Patricia; Lammer, Mónica; Cangelosi, Adriana; Mariconda, Virginia; Celi Castillo, Ana Beatriz; Brero, Luisa; Chacana, Pablo (Elsevier, 2021-07)
      Bee venom is a complex mixture of molecules, among which melittin and phospholipase A2 (PLA2) are the toxic components involved in envenoming accidents with multiple honeybee stings. Traditionally, the treatment of envenomings ...