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Developments in plant-based vaccines against diseases of concern in developing countries
(BENTHAM Open, 2010)Vaccination has been extensively used to prevent, eradicate and control infectious diseases. However, the development and implementation of new vaccines remains prohibitively expensive for middle and low income countries where ... -
Double-layered rotavirus-like particles are efficient carriers to elicit strong CTL responses to delivered heterologous antigens
(Elsevier, 2014-11)The first 92 amino acids of VP2 of rotavirus are dispensable for VLP assembly and can be replaced by heterologous reporter proteins without affecting either self-assembly of chimeric VP2 or the interaction with VP6 to ... -
Early protection against foot-and-mouth disease virus in cattle using an inactivated vaccine formulated with Montanide ESSAI IMS D 12802 VG PR adjuvant
(Elsevier, 2014-04-17)Foot and mouth disease is an acute disease of cattle with a broad distribution around the world. Due to the fast spread of FMDV infections, control measures must be applied immediately after an outbreak, such as the use ... -
Editorial : Foot-and-mouth disease epidemiology, vaccines and vaccination : moving forward
(Frontiers Media, 2023-06)Vaccination has played a major role in foot-and-mouth disease (FMD) control. There are different approaches to the design and implementation of vaccination campaigns, and epidemiological information is paramount in influencing ... -
Editorial : Vaccination strategies against ruminant infectious diseases
(Frontiers Media, 2023-05)Ruminant infectious diseases cause economic impact through losses in animal production and human health. Most of the commercially available veterinary vaccines are live attenuated or inactivated which induce different ... -
Efficacy of a BVDV subunit vaccine produced in alfalfa transgenic plants
(Elsevier, 2013-02-15)Bovine viral diarrhea virus (BVDV) is considered an important cause of economic loss within bovine herds worldwide. In Argentina, only the use of inactivated vaccines is allowed, however, the efficacy of inactivated BVDV ... -
Enterohemorrhagic Escherichia coli O157:H7 antigens produced in transgenic lettuce effective as an oral vaccine in mice
(Springer, 2023-10)Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is a food-borne pathogen where ruminant farm animals, mainly bovine, serve as reservoirs. Bovine vaccination has been used to prevent disease outbreaks, and the current ... -
Equine influenza virus in Asia: phylogeographic pattern and molecular features reveal circulation of an autochthonous lineage
(American Society for Microbiology, 2019-07)Equine influenza virus (EIV) causes severe acute respiratory disease in horses. Currently, the strains belonging to the H3N8 subtype are divided into two clades, Florida clade 1 (FC1) and Florida clade 2 (FC2), which emerged ... -
Estimating the protection afforded by foot-and-mouth disease vaccines in the laboratory
(Elsevier, 2019-09)Foot-and-mouth disease (FMD) vaccines must be carefully selected and their application closely monitored to optimise their effectiveness. This review covers serological techniques for FMD vaccine quality control, including ... -
Estudio de la relación del virus de la Bursitis Infecciosa con su hospedador. Análisis de la respuesta inmune y de la función y localización de la proteína viral VP5
(Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 2015)Las aves representan un eslabón fundamental en la economía internacional. A nivel mundial, alrededor del 40% de la carne consumida es de origen aviar. La industria avícola ha experimentado en los últimos años un crecimiento ... -
Estudios genómicos y funcionales en Anaplasma marginale y en bacterias intracelulares de la clase alfa-proteobacteria y su relación con la reducción del genoma
(Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 2013)La subdivisión α- de la clase proteobacteria representa un grupo sumamente diverso y heterogéneo de bacterias con una gran variabilidad en sus características genómicas, biológicas y ecológicas. Dentro de esta subdivisión ... -
Evaluación de proteínas de una isla de patogenicidad y de envolturas bacterianas de Escherichia coli 0157:H7 como vacunas para reducir su incidencia en bovinos
(Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, 2015-11)Escherichia coli enterohemorrágico (EHEC) es un patógeno que puede causar diarrea, colitis hemorrágica, y síndrome urémico hemolítico (SUH), una enfermedad sistémica grave que afecta principalmente a los niños. En Argentina ... -
Evaluation of a virulent strain of Mycobacterium avium subsp. Paratuberculosis used as a heat-killed vaccine
(Elsevier, 2021-11)Bovine paratuberculosis is one of the most important chronic infectious diseases in livestock. This disease is difficult to control because of its inefficient management (test and cull strategy and inadequate biosecurity). ... -
Evaluation of different heterologous prime-boost immunization strategies against Babesia bovis using viral vectored and protein-adjuvant vaccines based on a chimeric multi-antigen
(2016)Protection against the intraerythrocytic bovine parasite Babesia bovis requires both humoral and cellular immune responses. Therefore, tailored combinations of immunogens targeted at both arms of the immune system are ... -
Evaluation of the safety profile of the vaccine candidate Brucella melitensis 16MDvjbR strain in goats
(Elsevier, 2021-01)Small ruminant brucellosis is caused by the Gram negative cocci-bacillus Brucella (B.) melitensis, the most virulent Brucella species for humans. In goats and sheep, middle to late-term gestation abortion, stillbirths and ... -
Evidence of porcine circovirus type 2 and co-infection with ungulate protoparvovirus 1 (porcine parvovirus) in mummies and stillborn piglets in subclinically infected farm
(Elsevier, 2021-04)Porcine circovirus type 2 (PCV2) and protoparvovirus 1 (PPV) were detected as single infection (6/131) and (11/131) respectively, or co-infection (6/131) in fetuses and stillborn piglets from normal deliveries in a farm ... -
Expresión heteróloga y localización subcelular del candidato vacunal GPI4 de babesia bovis en el ciliado tetrahymena thermophila
(FundaVet, 2019-06)Los glicosilfosfatidilinositoles (GPIs) se encuentran en abundancia en la superficie de protozoos parásitos como glicolípidos libres y como anclas de proteínas de superficie a la membrana plasmática. Se ha demostrado que ... -
Identification of novel vaccine candidates against cryptosporidiosis of neonatal bovines by reverse vaccinology
(Elsevier, 2018-12)The apicomplexan protozoan Cryptosporidium parvum is an important causative agent of diarrhea of neonatal bovines. Vaccination has been proposed as an advantageous strategy against cryptosporidiosis of calves since besides ... -
Immune cells transferred by colostrum do not influence the immune responses to foot-and-mouth disease primary vaccination
(Elsevier, 2019-09)Little is known about the influence of maternal antibodies and immune cells transferred through colostrum on the immune responses of calves to the currently used foot-and-mouth disease (FMD) vaccines. Here we evaluated the ... -
Immunogenicity of hypothetical highly conserved proteins as novel antigens in Anaplasma marginale
(Springer, 2014-03)Anaplasma marginale is a tick-transmitted Gram-negative intraerythrocytic bacterium and the etiological agent of bovine Anaplasmosis. Even though considerable research efforts have been undertaken, Anaplasmosis vaccine ...