Browsing Centros e Institutos de Investigación by Subject "Vacuna"
Now showing items 21-40 of 56
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Estimating the protection afforded by foot-and-mouth disease vaccines in the laboratory
(Elsevier, 2019-09)Foot-and-mouth disease (FMD) vaccines must be carefully selected and their application closely monitored to optimise their effectiveness. This review covers serological techniques for FMD vaccine quality control, including ... -
Estudio de la relación del virus de la Bursitis Infecciosa con su hospedador. Análisis de la respuesta inmune y de la función y localización de la proteína viral VP5
(Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 2015)Las aves representan un eslabón fundamental en la economía internacional. A nivel mundial, alrededor del 40% de la carne consumida es de origen aviar. La industria avícola ha experimentado en los últimos años un crecimiento ... -
Estudios genómicos y funcionales en Anaplasma marginale y en bacterias intracelulares de la clase alfa-proteobacteria y su relación con la reducción del genoma
(Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 2013)La subdivisión α- de la clase proteobacteria representa un grupo sumamente diverso y heterogéneo de bacterias con una gran variabilidad en sus características genómicas, biológicas y ecológicas. Dentro de esta subdivisión ... -
Evaluación de proteínas de una isla de patogenicidad y de envolturas bacterianas de Escherichia coli 0157:H7 como vacunas para reducir su incidencia en bovinos
(Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, 2015-11)Escherichia coli enterohemorrágico (EHEC) es un patógeno que puede causar diarrea, colitis hemorrágica, y síndrome urémico hemolítico (SUH), una enfermedad sistémica grave que afecta principalmente a los niños. En Argentina ... -
Evaluation of a virulent strain of Mycobacterium avium subsp. Paratuberculosis used as a heat-killed vaccine
(Elsevier, 2021-11)Bovine paratuberculosis is one of the most important chronic infectious diseases in livestock. This disease is difficult to control because of its inefficient management (test and cull strategy and inadequate biosecurity). ... -
Evaluation of different heterologous prime-boost immunization strategies against Babesia bovis using viral vectored and protein-adjuvant vaccines based on a chimeric multi-antigen
(2016)Protection against the intraerythrocytic bovine parasite Babesia bovis requires both humoral and cellular immune responses. Therefore, tailored combinations of immunogens targeted at both arms of the immune system are ... -
Evaluation of the safety profile of the vaccine candidate Brucella melitensis 16MDvjbR strain in goats
(Elsevier, 2021-01)Small ruminant brucellosis is caused by the Gram negative cocci-bacillus Brucella (B.) melitensis, the most virulent Brucella species for humans. In goats and sheep, middle to late-term gestation abortion, stillbirths and ... -
Evidence of porcine circovirus type 2 and co-infection with ungulate protoparvovirus 1 (porcine parvovirus) in mummies and stillborn piglets in subclinically infected farm
(Elsevier, 2021-04)Porcine circovirus type 2 (PCV2) and protoparvovirus 1 (PPV) were detected as single infection (6/131) and (11/131) respectively, or co-infection (6/131) in fetuses and stillborn piglets from normal deliveries in a farm ... -
Expresión heteróloga y localización subcelular del candidato vacunal GPI4 de babesia bovis en el ciliado tetrahymena thermophila
(FundaVet, 2019-06)Los glicosilfosfatidilinositoles (GPIs) se encuentran en abundancia en la superficie de protozoos parásitos como glicolípidos libres y como anclas de proteínas de superficie a la membrana plasmática. Se ha demostrado que ... -
Identification of novel vaccine candidates against cryptosporidiosis of neonatal bovines by reverse vaccinology
(Elsevier, 2018-12)The apicomplexan protozoan Cryptosporidium parvum is an important causative agent of diarrhea of neonatal bovines. Vaccination has been proposed as an advantageous strategy against cryptosporidiosis of calves since besides ... -
Immune cells transferred by colostrum do not influence the immune responses to foot-and-mouth disease primary vaccination
(Elsevier, 2019-09)Little is known about the influence of maternal antibodies and immune cells transferred through colostrum on the immune responses of calves to the currently used foot-and-mouth disease (FMD) vaccines. Here we evaluated the ... -
Immunogenicity of hypothetical highly conserved proteins as novel antigens in Anaplasma marginale
(Springer, 2014-03)Anaplasma marginale is a tick-transmitted Gram-negative intraerythrocytic bacterium and the etiological agent of bovine Anaplasmosis. Even though considerable research efforts have been undertaken, Anaplasmosis vaccine ... -
Influence of antibodies transferred by colostrum in the immune responses of calves to current foot-and-mouth disease vaccines
(2014-11-12)Immunity to currently used oil-adjuvanted inactivated vaccines against foot-and-mouth disease virus (FMDV) has been studied in detail in adult animals; however, the influence of maternally derived antibodies transferred ... -
MANα1-2MAN decorated liposomes enhance the immunogenicity induced by a DNA vaccine against BoHV-1
(Wiley, 2020-07)New technologies in the field of vaccinology arise as a necessity for the treatment and control of many diseases. Whole virus inactivated vaccines and modified live virus ones used against Bovine Herpesvirus‐1 (BoHV‐1) ... -
Molecular engineering improves antigen quality and enables integrated manufacturing of a trivalent subunit vaccine candidate for rotavirus
(BMC, 2021-05)Background: Vaccines comprising recombinant subunit proteins are well-suited to low-cost and high-volume production for global use. The design of manufacturing processes to produce subunit vaccines depends, however, on the ... -
Mouse model as an efficacy test for foot‐and‐mouth disease vaccines
(Wiley, 2020-04)Protection against foot‐and‐mouth disease virus (FMDV) has been linked to the development of a humoral response. In Argentina, the official control tests for assessing the potency of FMD vaccines are protection against ... -
MVAΔ008 viral vector encoding the model protein OVA induces improved immune response against the heterologous antigen and equal levels of protection in a mice tumor model than the conventional MVA
(Elsevier, 2021-11)Modified vaccinia Ankara virus (MVA) is extensively used as a vaccine vector. We have previously observed that MVAΔ008, an MVA lacking the gene that codes for interleukin-18 binding protein, significantly increases CD8+ ... -
New scenarios for brucella suis and brucella melitensis
(Springer, 2017-03)Purpose of Review: We pretend to highlight the most important advances reached in the last few years in the biology of Brucella suis and Brucella melitensis and focus attention on new tools for the comprehension, prevention ... -
Novel expression of immunogenic foot-and-mouth disease virus-like particles in Nicotiana benthamiana
(2018-01)Foot-and-mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals and is endemic in Africa, parts of South America and southern Asia. The causative agent, FMD virus (FMDV) is a member of the genus ... -
Obtención de mutantes de Brucella abortus genéticamente definidas: su caracteización molecular y evaluación de su uso como vacunas para la brucelosis bovina
(Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 2017)El desarrollo de las técnicas de ADN recombinante permitió la generación de vacunas racionalmente diseñadas. Teniendo esto en cuenta, el objetivo de este trabajo es la obtención de cepas de Brucella abortus genéticamente ...