Now showing items 1-20 of 42

    • Analysing nonsynonymous mutations between two Mycobacterium bovis strains with contrasting pathogenic profiles 

      Bigi, María Mercedes; Vazquez, Cristina Lourdes; Castelão, Ana Beatriz C.; Garcia, Elizabeth Andrea; Cataldi, Angel Adrian; Jackson, Mary; McNeil, Michael; Soria, Marcelo Abel; Zumarraga, Martin Jose; Cabruja, Matias; Gago, Gabriela; Blanco, Federico Carlos; Nishibe, Christiane; Almeida Junior, Nalvo Franco de; Araujo, Flabio Ribeiro de; Bigi, Fabiana (Elsevier, 2019-12)
      Mycobacterium bovis (M. bovis) is the causative agent of bovine tuberculosis, a chronic infectious disease that can affect cattle, other domesticated species, wild animals and humans. This disease produces important economic ...
    • Bayesian assessment of the accuracy of a PCR-based rapid diagnostic test for bovine tuberculosis in swine 

      Barandiaran, Soledad; Perez Aguirreburualde, María Sol; Marfil, María Jimena; Martinez Vivot, Marcela; Aznar, Maria Natalia; Zumarraga, Martin Jose; Pérez, Andrés M. (Frontiers Media, 2019-06)
      Infection with the Mycobacterium bovis (M. bovis) causes a disease referred to as bovine tuberculosis (bTB), which affects a wide range of mammal hosts. Many countries have implemented control and eradication plans that ...
    • BoLA-DRB3 exon2 polymorphisms among tuberculous cattle: Nucleotide and functional variability and their association with bovine tuberculosis pathology 

      Eirin, Maria Emilia; Carignano, Hugo Adrian; Shimizu, Ernesto; Pando, Maria de los Angeles; Zumarraga, Martin Jose; Magnano, Gabriel; Macías, Analía; Garbaccio, Sergio Gabriel; Huertas, Pablo Sebastian; Morsella, Claudia Graciela; Ferrara Muñiz, Ximena; Cataldi, Angel Adrian; Paolicchi, Fernando; Poli, Mario Andres (Elsevier, 2020-06)
      Bovine tuberculosis (bTB) is caused by Mycobacterium bovis and disseminated worldwide. In Argentina, the highest prevalence occurs in dairy areas. BoLA DRB3.2 is related to the adaptive immunity in mycobacterial infections. ...
    • Desarrollo de alternativas diagnósticas de tuberculosis bovina 

      Leiva, Carlos (Universidad Nacional de Quilmes, 2015-02)
      En el siguiente trabajo se llevó cabo la puesta a punto y optimización de la técnica LAMP (del inglés loop-mediated isothermal amplification) para la detección de Mycobacterium bovis, agente etiológico de la tuberculosis ...
    • Detection of Mycobacterium bovis in Bovine and Bubaline tissues using Nested-PCR for TbD1 

      Araújo, Cristina Pires de; Osório, Ana Luiza Alves Rosa; Jorge, Klaudia dos Santos Goncalves; Ramos, Carlos Alberto N.; Filho, Antonio Francisco S.; Vidal, Carlos Eugênio Soto; Roxo, Eliana; Nishibe, Christiane; Almeida Junior, Nalvo Franco de; Júnior, Antônio A. F.; Silva, Marcio Roberto; Neto, Jose Diomedes Barbosa; Cerqueira, Valíria Duarte; Zumarraga, Martin Jose; Araujo, Flabio Ribeiro de (PLOS, 2014-03)
      In the present study, a nested-PCR system, targeting the TbD1 region, involving the performance of conventional PCR followed by real-time PCR, was developed to detect Mycobacterium bovis in bovine/bubaline tissue homogenates. ...
    • Detection of Mycobacterium bovis–infected dairy herds using PCR in bulk tank milk samples 

      Zumarraga, Martin Jose; Soutullo, Adriana; Garcia, Maria Ines; Marini, M. Rocío; Abdala, Alejandro Ariel; Tarabla, Hector Dante; Echaide, Susana T. de; Lopez, Marcela; Zervini, Elsa; Canal, Ana María; Cataldi, Angel Adrian (Mary Ann Liebert Inc., 2012-02)
      Bovine tuberculosis (bTB) is a chronic and zoonotic disease due to Mycobacterium bovis. The tuberculosis eradication campaign carried out in Argentina has considerably improved the health situation of the herds. Here we ...
    • Development and diagnostic validation of an ELISA based on an antigenic mixture for the detection of bovine tuberculosis 

      Griffa, Natanael; Moyano, Roberto Damián; Canal, Ana María; Traveria, Gabriel Eduardo; Santangelo, María De La Paz; Alonso, Maria Natalia; Romano, Maria Isabel (Elsevier, 2020-02)
      Programs for the eradication of bovine tuberculosis (bTB) focus on the tuberculin skin test (TST) and slaughter of reactor cattle. However, the disease remains an animal health concern in several countries and improving ...
    • Development of a lateral flow immunochromatography test for the rapid detection of bovine tuberculosis 

      Alonso, Maria Natalia; Griffa, Natanael; Moyano, Roberto Damián; Mon, Maria Laura; Colombatti Olivieri, Maria Alejandra; Barandiaran, Soledad; Martinez Vivot, Marcela; Fiorini, Gonzalo; Canal, Ana María; Santangelo, María De La Paz; Singh, Mahavir G.; Romano, Maria Isabel (Elsevier, 2021-04)
      Detection of specific antibodies would be a useful test strategy for bovine tuberculosis (bTB) as a complement to the single skin test. We developed a lateral flow immunochromatography (LFIC) test for rapid bTB detection ...
    • Diagnóstico bacteriológico de tuberculosis bovina en bovinos reactores positivos a la prueba tuberculínica 

      Garbaccio, Sergio Gabriel; Delgado, Fernando Oscar; Zumarraga, Martin Jose; Rodriguez, Liliana Rita; Huertas, Pablo Sebastian; Garro, Carlos Javier (2018-04)
      Mycobacterium bovis es el agente causal de la tuberculosis bovina (TBB), enfermedad zoonótica que afecta la producción láctea y cárnica. En nuestro país, el diagnóstico se realiza a través de la prueba tuberculínica o ...
    • Enzyme-linked immunosorbent assay as complement of intradermal skin test for the detection of mycobacterium bovis infection in cattle 

      Garbaccio, Sergio Gabriel; Garro, Carlos Javier; Delgado, Fernando Oscar; Tejada, G. A.; Eirin, Maria Emilia; Huertas, Pablo Sebastian; Leon, Emilio Arnaldo; Zumarraga, Martin Jose (Elsevier, 2019-07)
      Diagnostic tests based on cell-mediated immunity are used in programs for the control and eradication of bovine tuberculosis (bTB), which is mainly caused by Mycobacterium bovis. Additional serological assays could be ...
    • ERAP1 and PDE8A are downregulated in cattle protected against bovine tuberculosis 

      Blanco, Federico Carlos; Soria, Marcelo Abel; Klepp, Laura Ines; Bigi, Fabiana (Karger, 2017-12)
      Bovine tuberculosis (bTB) is a zoonotic disease caused by Mycobacterium bovis that is responsible for significant economic losses worldwide. In spite of its relevance, the limited knowledge about the host immune responses ...
    • Exploring the association between polymorphisms at 3’UTR SLC11A1 gene microsatellites and resistance to tuberculosis: A case-control study in Bos taurus dairy cattle 

      Hasenauer, Flavia Carolina; Garbaccio, Sergio Gabriel; Caffaro, María Eugenia; Garro, Carlos Javier; Huertas, Pablo Sebastian; Poli, Mario Andres; Rossetti, Carlos Alberto (2018-04)
      Bovine tuberculosis is a contagious infectious disease that causes significant economic impact in dairy and meat farms throughout the world. Multiple factors, including host genome, determine the outcome of the infection. ...
    • FasR regulates fatty acid biosynthesis and is essential for virulence of Mycobacterium tuberculosis 

      Mondino, Sonia; Vazquez, Cristina Lourdes; Cabruja, Matias; Sala, Claudia; Cazenave-Gassiot, Amaury; Blanco, Federico Carlos; Wenk, Markus R.; Bigi, Fabiana; Cole, Stewart T.; Gramajo, Hugo; Gago, Gabriela (Frontiers Media, 2020-10)
      Mycobacterium tuberculosis, the etiologic agent of human tuberculosis, is the world’s leading cause of death from an infectious disease. One of the main features of this pathogen is the complex and dynamic lipid composition ...
    • Fitness of drug resistant Mycobacterium tuberculosis and the impact on the transmission among household contacts 

      Morcillo, Nora; Imperiale, Belen Rocio; Di Giulio, Angela Beatríz; Zumarraga, Martin Jose; Takif, Howard; Cataldi, Angel Adrian (Elsevier, 2014-12)
      There has been an on-going debate on whether the development of drug resistance in Mycobacterium tuberculosis reduces its relative fitness and its ability to cause disease. The aim of this study was to explore this ...
    • Ganadería bovina en el área de influencia de la EEA INTA San Pedro. Recomendaciones sobre sanidad, nutrición y manejo. Abril 2020 

      Gamietea, Ignacio José; Garbaccio, Sergio Gabriel (EEA San Pedro, INTA, 2020)
      Trata de cuatro acciones clave en los rodeos de cría bovina de la provincia de Buenos Aires. Las cuatro están ligadas al periodo postservicio: evaluaciones ginecológica, de estado corporal y dentaria de los vientres y ...
    • Genotyping Mycobacterium bovis from cattle in the Central Pampas of Argentina: tempoal and regional trends 

      Shimizu, Ernesto; Macias, Analía; Paolicchi, Fernando; Magnano, Gabriel; Zapata, Laura; Fernandez, Analía; Canal, Ana María; Garbaccio, Sergio Gabriel; Cataldi, Angel Adrian; Caimi, Karina Cynthia; Zumarraga, Martin Jose (Fundacao Oswaldo Cruz, Brasil, 2014-04)
      Mycobacterium bovis is the causative agent of bovine tuberculosis (TB), a disease that affects approximately 5% of Argentinean cattle. Among the molecular methods for genotyping, the most convenient are spoligotyping and ...
    • La genómica de las micobacterias 

      Viale, Mariana; Zumarraga, Martin Jose; Araujo, Flabio Ribeiro de; Zarraga, Ana Maria; Cataldi, Angel Adrian; Romano, Maria Isabel; Bigi, Fabiana (Office International des Epizooties, 2016)
      Las especies Mycobacterium bovis y Mycobacterium avium subsp. paratuberculosis son los agentes causales de la tuberculosis y la paratuberculosis en animales, respectivamente. Además, ambas micobacterias, pero fundamentalmente ...
    • Identificación de factores de riesgo de tuberculosis bovina en rodeos lecheros 

      Garro, Carlos Javier (Facultad de Ciencias Agrarias, Universidad Nacional de Mar del Plata, 2009-09)
      La tuberculosis bovina (TBB), producida por el Mycobacterium bovis (M. bovis), es una enfermedad zoonótica endémica en los rodeos bovinos de la Argentina. La información sobre la asociación entre el manejo y la ocurrencia ...
    • Identification and evaluation of new Mycobacterium bovis antigens in the in vitro interferon gamma release assay for bovine tuberculosis diagnosis 

      Eirin, Maria Emilia; Macías, Analía; Magnano, Gabriel; Morsella, Claudia Graciela; Mendez, Laura Luján; Blanco, Federico Carlos; Bianco, María Veronica; Severina, Walter; Alito, Alicia Elsa; Pando, Maria de los Angeles; Singh, Mahavir G.; Spallek, Ralph; Paolicchi, Fernando; Bigi, Fabiana; Cataldi, Angel Adrian (Elsevier, 2015-12)
      Bovine tuberculosis (bTB) is a common zoonotic disease, caused by Mycobacterium bovis (M. bovis), responsible for significant economic losses worldwide. Its diagnosis is based on the detection of cell mediated immunity ...
    • Identification of bovine tuberculosis biomarkers to detect tuberculin skin test and IFNγ release assay false negative cattle 

      Klepp, Laura Ines; Eirin, Maria Emilia; Garbaccio, Sergio Gabriel; Soria, Marcelo Abel; Bigi, Fabiana; Blanco, Federico Carlos (Elsevier, 2019-02)
      Bovine tuberculosis (bTB) is an important animal and zoonotic disease, which causes severe economic losses. The main focus of this study was to assess the predictive power of previously identified biomarkers of bTB in ...