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IFNG-mediated immune responses enhance autophagy against Mycobacterium tuberculosis antigens in patients with active tuberculosis
Rovetta, Ana Inés; Peña, Delfina; Hernández del Pino, Rodrigo Emanuel; Recalde, Gabriela María; Pellegrini, Joaquín Miguel; Bigi, Fabiana; Musella, Rosa María; Palmero, Domingo; Gutierrez, Marisa; Colombo, Maria Isabel; García, Verónica Edith (Taylor & Francis, 2014-11)Protective immunity against Mycobacterium tuberculosis (Mtb) requires IFNG. Besides, IFNG-mediated induction of autophagy suppresses survival of virulent Mtb in macrophage cell lines. We investigated the contribution of ... -
Infectious bursal disease virus assembly causes endoplasmic reticulum stress and lipid droplet accumulation
Frontini-López, Yesica R.; Rivera, Lautaro; Pocognoni, Cristian A.; Roldán, Julieta Suyai; Colombo, Maria Isabel; Uhart, Marina; Delgui, Laura Ruth (MDPI, 2023-06)Gumboro illness is caused by the highly contagious immunosuppressive infectious bursal disease virus (IBDV), which affects the poultry industry globally. We have previously shown that IBDV hijacks the endocytic pathway to ...