• A new passive immune strategy based on IgY antibodies as a key element to control neonatal calf diarrhea in dairy farms 

      Vega, Celina Guadalupe; Bok, Marina; Ebinger, Maren; Rocha, Lucía Alejandra; Rivolta, Alejandra Antonella; González Thomas, Valeria; Muntadas, Pilar; D’Aloia, Ricardo; Pinto, Verónica; Parreño, Viviana; Wigdorovitz, Andres (BMC, 2020-07)
      Background: Neonatal diarrhea remains one of the main causes of morbi-mortality in dairy calves under artificial rearing. It is often caused by infectious agents of viral, bacterial, or parasitic origin. Cows vaccination ...
    • A novel MHC-II targeted BVDV subunit vaccine induces a neutralizing immunological response in guinea pigs and cattle 

      Bellido, Demian; Baztarrica, Josefina; Rocha, Lucía Alejandra; Pecora, Andrea; Acosta, Mario; Escribano, José M.; Parreño, Gladys; Wigdorovitz, Andres (Wiley, 2021-11)
      Bovine viral diarrhoea virus (BVDV) is a major cause of economic loss in the cattle industry, worldwide. Infection results in reduced productive performance, growth retardation, reduced milk production and increased ...
    • An indirect ELISA validated as diagnostic and vaccines quality control tool for bovine parainfluenza virus TYPE 3 (BPIV3) 

      Odeon, Maria Mercedes; Maidana, Silvina Soledad; Ferrecio, Carola Maria; Grazziotto, Noelia Magali; Pisano, Eddie; Alvarez, Irene; Rocha, Lucía Alejandra; Parreño, Gladys Viviana; Romera, Sonia Alejandra (CNRS (Francia), 2021-07)
      Serological assays, including enzyme-linked immunosorbent assays (ELISA), provide a useful tool to screen animals for the presence of antibodies (Abs) against a wide range of infectious agents (including viruses that cause ...
    • Development of a platform process for the production and purification of single‐domain antibodies 

      Crowell, Laura E.; Goodwine, Chaz; Sosa Holt, Carla Solange; Rocha, Lucía Alejandra; Vega, Celina Guadalupe; Rodriguez-Aponte, Sergio A.; Dalvie, Neil C.; Tracey, Mary Kate; Puntel, Mariana; Wigdorovitz, Andres; Parreño, Gladys; Love, Kerry R.; Cramer, Steven M.; Love, J. Christopher (Wiley, 2021-09)
      Single-domain antibodies (sdAbs) offer the affinity and therapeutic value of conventional antibodies, with increased stability and solubility. Unlike conventional antibodies, however, sdAbs do not benefit from a platform ...