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Bovine colostral cells : the often forgotten component of colostrum
Gonzalez, Diego; Dus Santos, Maria Jose (American Veterinary Medical Association, 2017-05)Because bovine maternal and fetal blood supplies are kept separate in utero, calves are immunologically naïve immediately after birth, which puts them at high risk for disease. The acquisition of passive immunity, generally ... -
Bovine colostral cells—the often forgotten component of colostrum
Gonzalez, Diego; Dus Santos, Maria Jose (American Veterinary Medical Association, 2017-05)At birth, neonatal calves have all the essential immune components they need as adult cattle; however, it takes at least 2 to 4 weeks for those components to become fully functional.1,2 The immune system does not become ... -
Bovine respiratory syncytial virus seroprevalence and risk factors in feedlot cattle from Córdoba and Santa Fe, Argentina = Seroprevalencia del virus respiratorio sincicial bovino y factores de riesgo asociados en engordes a corral de Córdoba y Santa Fe, Argentina
Ferella, Alejandra; Perez Aguirreburualde, María Sol; Margineda, Carlos Augusto; Aznar, Maria Natalia; Sammarruco, Romina Ayelén; Dus Santos, Maria Jose; Mozgovoj, Marina Valeria (2018-09)Bovine respiratory syncytial virus (BRSV) is one of the causative agents of respiratory disease in cattle all over the world, leading to important economic losses. The aim of this work was to determine the seroprevalence ... -
Brucella spp. Lumazine synthase as a novel immunomodulator to produce egg yolk antibodies
Bellido, Demian; Chacana, Pablo; Mozgovoj, Marina Valeria; Gonzalez, Diego; Goldbaum, Fernando Alberto; Wigdorovitz, Andres; Dus Santos, Maria Jose (Scientific Research, 2012-02)Lumazine synthase from Brucella spp. (BLS) is a highly immunogenic decameric protein. It has been previously described as a carrier of peptides or proteins to increase their immunogenicity in different animal species, but ... -
Chicken egg yolk antibodies against bovine respiratory syncytial virus neutralize the virus in vitro
Ferella, Alejandra; Bellido, Demian; Chacana, Pablo; Wigdorovitz, Andres; Dus Santos, Maria Jose; Mozgovoj, Marina Valeria (Elsevier, 2012)Bovine respiratory syncytial virus (BRSV) and its counterpart in humans (HRSV) are two closely related virus, which are the leading cause of severe respiratory syndrome in calves and young children, respectively. Passive ... -
Development of an APC-targeted multivalent E2-based vaccine against Bovine Viral Diarrhea Virus types 1 and 2
Pecora, Andrea; Malacari, Darío Amilcar; Pérez Aguirreburualde, María Sol; Bellido, Demian; Nuñez, Maria del Carmen; Dus Santos, Maria Jose; Martínez Escribano, José Angel; Wigdorovitz, Andres (Elsevier, 2015-09)The aim of this study was to develop and test a multivalent subunit vaccine against Bovine Viral Diarrhea Virus (BVDV) based on the E2 virus glycoprotein belonging to genotypes 1a, 1b and 2a, immunopotentiated by targeting ... -
Dynamics of neutralizing antibodies against Bovine respiratory syncytial virus in a dairy herd from Santa Fe Province, Argentina = Dinámica de anticuerpos neutralizantes contra el virus respiratorio sincitial bovino en un rodeo lechero de la provincia de Santa Fe, Argentina
Ferella, Alejandra; Perez Aguirreburiald, Maria Sol; Sammarruco, Romina Ayelén; Parreño, Viviana; Dus Santos, Maria Jose; Mozgovoj, Marina Valeria (Elsevier, 2020-05)Bovine respiratory syncytial virus (BRSV) is one of the most relevant agents responsible for respiratory disease in cattle from both dairy and beef farms. BRSV is spread by horizontal contact causing a constant presence ... -
Efficacy of a BVDV subunit vaccine produced in alfalfa transgenic plants
Perez Aguirreburialde, Maria Sol; Gomez, Maria Cristina; Ostachuck, Agustín; Wolman, Federico Javier; Albanesi, Guillermo Luis; Pecora, Andrea; Odeon, Anselmo Carlos; Ardila, Fernando Jorge; Escribano, José M.; Dus Santos, Maria Jose; Wigdorovitz, Andres (Elsevier, 2013-02-15)Bovine viral diarrhea virus (BVDV) is considered an important cause of economic loss within bovine herds worldwide. In Argentina, only the use of inactivated vaccines is allowed, however, the efficacy of inactivated BVDV ... -
Estudio de la respuesta inmune frente a la vacunación con virus respiratorio sincitial bovino (VRSB) inactivado en bovinos. Evaluación de la inmunidad pasiva
Margineda, Carlos Augusto; Ferella, Alejandra; Perez Aguirreburialde, Maria Sol; Sammarruco, Romina Ayelén; Gonzalez, Diego; Toledo, Gabriela Fernanda; Dus Santos, Maria Jose; Mozgovoj, Marina Valeria (Ediciones INTA, 2019-04)El objetivo de este trabajo fue evaluar el título y la duración de anticuerpos neutralizantes (AN) en vacas inmunizadas con una vacuna experimental inactivada para el virus respiratorio sincitial bovino (VRSB) y los niveles ... -
Molecular characterization of pestiviruses in fetal bovine sera originating from Argentina: evidence of circulation of HoBi-like viruses
Pecora, Andrea; Perez Aguirreburiald, Maria Sol; Ridpath, Julia; Dus Santos, Maria Jose (Frontiers Media, 2019-10)Serological evidence suggests that HoBi-like viruses, an emerging species within the Pestivirus genus of the Flaviviridae family, are in circulation in Argentina. While HoBi-like viruses were first isolated from Brazilian ... -
Pestivirus emergentes HoBi : impacto en salud animal y su importancia como contaminante de insumos biotecnológicos
Pecora, Andrea; Pérez Aguirreburualde, María Sol; Malacari, Darío Amilcar; Zabal, Osvaldo Alfredo; Bauermann, Fernando Viçosa; Ridpath, Julia; Dus Santos, Maria Jose (Gerencia de Comunicación e Imagen Institucional, DNA SICC, INTA, 2016-11-02)Los virus HoBi son un grupo de Pestivirus emergentes que afecta a bovinos y bubalinos y son contaminantes muy comunes de productos biológicos. Luego de ser identificados por primera vez en Alemania a partir muestras ... -
Plant‐produced viral bovine vaccines: what happened during the last 10 years?
Ruiz, Vanesa; Mozgovoj, Marina Valeria; Dus Santos, Maria Jose; Wigdorovitz, Andres (Wiley, 2015-10)Vaccination has proved to be an efficient strategy to deal with viral infections in both human and animal species. However, protection of cattle against viral infections is still a major concern in veterinary science. ... -
Quantitation of cytokine gene expression by real time PCR in bovine milk and colostrum cells from cows immunized with abovine rotavirus VP6 experimental vaccine
Gonzalez, Diego; Rimondi, Agustina; Perez Aguirreburialde, Maria Sol; Mozgovoj, Marina Valeria; Bellido, Demian; Wigdorovitz, Andres; Dus Santos, Maria Jose (Elsevier, 2013-10)In a previous work, VP6 recombinant protein was produced using baculovirus system and it was evaluated in a colostrum-deprived calf model. This vaccine was able to protect calves against viral challenge without inducing ... -
Serologic evidence of HoBi-like virus circulation in Argentinean water buffalo
Pecora, Andrea; Perez Aguirreburualde, María Sol; Malacari, Darío Amilcar; Zabal, Osvaldo Alfredo; Sala, Juan Manuel; Konrad, Jose Luis; Caspe, Sergio Gaston; Bauermann, Fernando; Ridpath, Julia; Dus Santos, Maria Jose (2017-11)HoBi-like pestiviruses (also known as bovine viral diarrhea virus 3) have been sporadically reported from naturally infected cattle in Brazil, Asia, and Europe. Although HoBi-like viruses seem to be endemic in Brazilian ...